Adiponectin/Acrp30 Antibody (RM0072-7J611)



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Adiponectin/Acrp30 Antibody (RM0072-7J611) Summary

Mouse recombinant Adiponectin
This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant Adiponectin.
Protein G purified
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Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.2 um filtered solution in PBS.
Sodium Azide
LYOPH mg/ml
Protein G purified
Reconstitution Instructions
Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.


Application Notes
This antibody detects mouse Adiponectin in Western blotting. It is crossreactive to human Adiponectin protein in Western blotting.

Reactivity Notes



Adipose cells produce and secrete numerous physiologically important proteins, such as Lipoprotein Lipase, Leptin, and Adipocyte Complement Related protein of 30 kDa, also known as Acrp30 or Adiponectin. Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes. During adipocyte differentiation, Adiponectin mRNA is induced >100 fold. Adiponectin improves the ability of insulin to suppress glucose production, at sub physiological levels, thereby linking adipose tissue to whole body glucose regulation. Adiponectin function appears to be regulated by phosphatidylinositol 3 kinase (PI3K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase. Adiponectin mRNA is significantly reduced in adipose tissue of obese patients with Type 2 diabetes. The structural similarity of Adiponectin to TNF alpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes. Adiponectin is implicated as a regulator of whole body energy homeostasis.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product PDFs


Gene Symbol ADIPOQ

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