Adiponectin/Acrp30 Antibody (Adn23)

Images

 
Western Blot: Adiponectin/Acrp30 Antibody (Adn23) [NB100-72984] - SDS-electrophoresis in reducing conditions and WBing of native purified adiponectin from human plasma.
Western Blot: Adiponectin/Acrp30 Antibody (Adn23) [NB100-72984] - Immunodetection of native adiponectin with anti-Adn MAbs in WB after SDS-electrophoresis in reducing conditions. Lane 1 Adn20 Lane 2 Adn23 Lane 3 Adn63 ...read more
ELISA: Adiponectin/Acrp30 Antibody (Adn23) [NB100-72984] - Curve: adiponectin monoclonal antibody[NB100-72984]-Serum titration curve for the assay Adn20-Adn23. Pooled normal human serum was serially diluted with ...read more
ELISA: Adiponectin/Acrp30 Antibody (Adn23) [NB100-72984] - Curve: adiponectin monoclonal antibody[NB100-72984]-Immunoreactivity in protein fractions after size-exclusion chromatography, measured by assay Adn20-Adn23. 1 ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-72984
    • Availability
      Product Discontinued

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Adiponectin/Acrp30 Antibody (Adn23) Summary

Immunogen
Human serum adiponectin.
Specificity
Human serum adiponectin.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
ADIPOQ
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Positive Control
Adiponectin/Acrp30 Lysate (NBL1-07342)

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Adiponectin/Acrp30 Antibody (Adn23)

  • ACDC
  • Acrp30
  • ACRP30ADPN
  • adipocyte, C1Q and collagen domain containing
  • Adiponectin
  • adiponectin, C1Q and collagen domain containing
  • AdipoQ
  • ADIPQTL1
  • ApM1
  • apM-1
  • APM1APM-1
  • C1q and collagen domain-containing protein
  • GBP28
  • GBP28apM1
  • Gelatin-binding protein

Background

Adipose cells produce and secrete numerous physiologically important proteins, such as Lipoprotein Lipase, Leptin, and Adipocyte Complement Related protein of 30 kDa, also known as Acrp30 or Adiponectin. Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes. During adipocyte differentiation, Adiponectin mRNA is induced >100 fold. Adiponectin improves the ability of insulin to suppress glucose production, at sub physiological levels, thereby linking adipose tissue to whole body glucose regulation. Adiponectin function appears to be regulated by phosphatidylinositol 3 kinase (PI3K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase. Adiponectin mRNA is significantly reduced in adipose tissue of obese patients with Type 2 diabetes. The structural similarity of Adiponectin to TNF alpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes. Adiponectin is implicated as a regulator of whole body energy homeostasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol ADIPOQ
Entrez