Adenovirus Fiber Antibody (4D2) Summary
UV-irradiated Ad2 virus
Protein A purified
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- Western Blot 1:100 - 1:2000
- Immunofluorescence 1:10 - 1:500
Human reported in literature (PMID: 15756711). Hamster reactivity reported in scientific literature (see Ying B et all 2009). Mouse reactivity reported in scientific literature (see Jiang H et all 2009).
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
10mM PBS (pH 7.4) and 0.2% BSA
0.09% Sodium Azide
Protein A purified
Alternate Names for Adenovirus Fiber Antibody (4D2)
- Fiber protein
- Virus attachment protein
Adenovirus capsid proteins are synthesized in the cytoplasm and transported to the nucleus for assembly into the virus particles. The three major capsid proteins (hexon, penton base, and fiber) are synthesized late in infection. Fiber plays a crucial role in adenovirus infection by attaching the virus to a specific receptor on the cell surface. Ad2 and Ad5 fibers are proposed to consist of three domains: an N-terminal tail that interacts with penton base, a shaft composed of 22 repeats of a 15 amino acid segment that forms beta-sheet and beta-bends, and a knob at the C-terminus that contains the type-specific antigen and is responsible for binding to the cell surface receptor. It is shown that the fiber of Ad2 is most likely a trimer when found on the viron.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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FAQs for Adenovirus Fiber Antibody (NB600-541). (Showing 1 - 1 of 1 FAQ).
Is there an accession number for the antigen recognized by this antibody? Is the epitope located on the N-terminus?
- This antibody recognizes the N-terminus. There is no accession number associated with this target.
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