ADAMTS4 Antibody


Immunohistochemistry-Paraffin: ADAMTS4 Antibody [NBP1-02413] - Staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 more

Product Details

Reactivity Hu, Ca, EqSpecies Glossary
Applications IHC, IHC-P
1.0 mg/ml

Order Details

ADAMTS4 Antibody Summary

A 17 amino acid synthetic peptide within the C-terminal of human ADAMTS4.
Human ADAMTS4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Bovine (94%), Bat (94%)
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Orangutan (100%), Gibbon (100%), Marmoset (94%), Elephant (94%), Panda (94%), Monkey (88%), Porcine (88%), Opossum (88%), Mouse (82%), Rat (82%), Hamster (82%)

Alternate Names for ADAMTS4 Antibody

  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 4
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • ADAM-TS 4
  • ADAMTS-2
  • ADAM-TS4
  • ADAMTS-4
  • ADMP-1
  • ADMP-1EC
  • Aggrecanase 1
  • aggrecanase-1
  • EC 3.4.24
  • KIAA0688A disintegrin and metalloproteinase with thrombospondin motifs 4


ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan and the brain extracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signal sequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and a C-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has been implicated in inflammatory joint diseases, and it also may be a factor in the progression of glioma and Alzheimer's disease.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies


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Product PDFs


Gene Symbol ADAMTS4

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