ACTR1A Antibody

Product Discontinued

ACTR1A Antibody Summary

• Immunogen: ACTR1A (-, 1 a.a. ~ 376 a.a) full-length human protein.MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSR
• Specificity: ACTR1A - ARP1 actin-related protein 1 homolog A, centractin alpha (yeast),
• Clonality: Polyclonal
• Host: Mouse
• Gene: ACTR1A
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against transfected lysate and tissue lysate for Western Blot. Has also been used for ELISA.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: This is unpurified antiserum so it is not possible to supply the specific antibody concentration.
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ACTR1A Antibody

• Actin-RPV
• alpha-centractin
• ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha)
• ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
• ARP1actin-RPV
• centractin
• Centrosome-associated actin homolog
• CTRN1
• FLJ52695
• FLJ52800
• FLJ55002

Background

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACTR1A
• Entrez:
  • 10121(Human)
• Uniprot:
  • NP_005727.1(Human)