ABI1 Antibody

Product Discontinued

ABI1 Antibody Summary

• Immunogen: A synthetic peptide (WYEGVCNRVTGL) corresponding to a region (483-494) from human Abelson interactor 1 (ABI1). To enhance the immunological response, this peptide was coupled to carrier protein BSA.
• Specificity: The specificity of this antibody has been confirmed by WB and IHC against the antigen.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ABI1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 0.5-1.0 ug/ml
  • Western Blot 1.0-2.0 ug/ml
• Application Notes: This antibody is useful in Immunohistochemistry-Paraffin and Western Blot. Human ABI1 (isoform 1) has a predicted length of 508 residues and MW of 55 kDa.

Reactivity Notes

Cross reacts with Human, Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 mg DiSodium Phosphate, 0.9 mg NaCl and 5 mg BSA
• Preservative: 0.05mg Sodium Azide
• Concentration: LYOPH
• Purity: Immunogen affinity purified
• Reconstitution Instructions: Please contact technical support for detailed reconstituion instruction.

Notes

Reconstitute in 0.1 ml of sterile distilled water to achieve an antibody concentration of 1 mg/ml. Centrifuge to remove any insoluble material.

Alternate Names for ABI1 Antibody

• Abelson interactor 1
• ABI1
• ABI-1
• abl interactor 1
• Abl-binding protein 4
• ABLBP4
• abl-interactor 1
• Abl-interactor protein 1 long
• E3B1
• eps8 binding protein
• Eps8 SH3 domain-binding protein
• Eps8-binding protein
• interactor protein AblBP4
• nap1 binding protein
• Nap1-binding protein
• NAP1BP
• spectrin SH3 domain binding protein 1
• Spectrin SH3 domain-binding protein 1
• SSH3BP
• SSH3BP1

Background

The protein encoded by this gene has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, the encoded protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling. Several transcript variants encoding multiple isoforms have been found for this gene. Transcript Variant: This variant (4) lacks two alternate in-frame coding exons compared to variant 1. The resulting isoform (d) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. This product is distributed on behalf of Biosensis Pty. Ltd. of Australia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ABI1