ABCD1 Antibody

Product Discontinued

ABCD1 Antibody Summary

• Immunogen: The antiserum was produced against synthesized peptide derived from human ABCD1. The immunogen region is: Internal.
• Specificity: ABCD1 Antibody detects endogenous levels of total ABCD1 protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ABCD1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:4000
  • Western Blot 1:500-1:1000

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ABCD1 Antibody

• Adrenoleukodystrophy protein
• ALDATP-binding cassette sub-family D member 1
• ALDPadrenoleukodystrophy
• AMNABC42
• ATP-binding cassette, sub-family D (ALD), member 1

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ABCD1
• Uniprot:
  • P33897(Human)