AAV Antibody

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Product Details

Summary
Reactivity NA, ViSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

AAV Antibody Summary

Immunogen
Synthetic peptide within residues 70-90 of major coat protein VP3 [AAV 2], residues 270-290 of capsid protein VP1 [AAV 6], and residues 270-290 of capsid AAV 3].
Specificity
Adeno-Associated Virus (AAV)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AAVS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry
Application Notes
This antibody is useful for Western Blot. Use in Immunohistochemistry reported in scientific literature (PMID 27591535).
Publications
Read Publication using NB100-93575.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for AAV Antibody

  • AAV
  • adeno-associated virus integration site 1

Background

Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). Forty-seven known serotypes have been isolated since they were first discovered in 1953 with 3 types known to cause gastroenteritis. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterised by inflammation of conjunctivae and the respiratory tract. The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections. It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated causing disease. The adenovirus early gene products E1A is a potent stimulator of cellular proliferation, which when overexpressed can overcome the growth inhibitory effects of TGF beta. The E1A region encodes a series of related proteins (35 - 46 kD) with multifunctional capabilities and forms a specific complex with the retinoblastoma tumor suppressor gene product. The E1a and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for AAV Antibody (NB100-93575)(1)

We have publications tested in 1 application: IHC.


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IHC
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for AAV Antibody (NB100-93575). (Showing 1 - 1 of 1 FAQ).

  1. One of our customers would like to know whether any of these anti-AAV antibodies were neutralizing and prevented transfection (cat# NB100-93575, NB100-93576, NB100-93577). Do you have data or maybe a customer feedback about it?
    • Unfortunately we have not received any data on testing of this either from our lab or from customer feedback about neutralizing and preventing transfection.

Secondary Antibodies

 

Isotype Controls

Additional AAV Products

AAV NB100-93575

Bioinformatics Tool for AAV Antibody (NB100-93575)

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Diseases for AAV Antibody (NB100-93575)

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Bioinformatics

Gene Symbol AAVS1
Entrez
Uniprot