15-PGDH/HPGD Antibody [FITC] Summary
Immunogen |
Purified type I human placental 15-PGDH protein [UniProt# P15428] |
Localization |
Cytoplasmic |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
HPGD |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/Immunofluorescence
- Immunohistochemistry
- Immunohistochemistry-Frozen
- Immunohistochemistry-Paraffin
|
Application Notes |
This 15-PGDH antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin-embedded sections and Western blot. In Western blot bands may be seen at 29 kDa and 58 kDa (homodimer) depending on the lysate used. In ICC/IF cytoplasmic staining was observed in HeLa cells. |
Reactivity Notes
Mouse reactivity reported in scientific literature (PMID: 27140190) Human reactivity reported in scientific literature (PMID:33210098).
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A purified |
Notes
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for 15-PGDH/HPGD Antibody [FITC]
Background
15-PGDH (15-hydroxyprostaglandin dehydrogenase, NAD+ or HPGD) belongs to short-chain dehydrogenases/reductases (SDR) family and is a key enzyme responsible for biological inactivation of prostaglandins as well as related eicosanoids. 15-PGDH has a potential to catalyze NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4, and it brings about prostaglandin inactivation for regulating biological processes which are controlled by prostaglandin levels. It is down-regulated by cortisol, dexamethasone and betamethasone, and TGFB1. 15-PGDH is considered as a tumor suppressor and its decreased expression is observed in cancers subjects with colorectal, breast, prostate, lung, thyroid, gastric and other cancers. Furthermore, defects in 15-PGDH gene have been linked to diseases including hypertrophic osteoarthropathy, primary, autosomal recessive, type 1 (PHOAR1), cranioosteoarthropathy (COA), isolated congenital nail clubbing (ICNC).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-Fr, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ELISA, ICC/IF
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Species: Hu, Rt
Applications: WB, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, ICC, KO
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, S-ELISA
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P
Publications for 15-PGDH/HPGD Antibody (NB200-179F) (0)
There are no publications for 15-PGDH/HPGD Antibody (NB200-179F).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for 15-PGDH/HPGD Antibody (NB200-179F) (0)
There are no reviews for 15-PGDH/HPGD Antibody (NB200-179F).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for 15-PGDH/HPGD Antibody (NB200-179F) (0)
Secondary Antibodies
| |
Isotype Controls
|
Other Available Formats
Additional 15-PGDH/HPGD Products
Bioinformatics Tool for 15-PGDH/HPGD Antibody (NB200-179F)
Discover related pathways, diseases and genes to 15-PGDH/HPGD Antibody (NB200-179F). Need help?
Read the
Bioinformatics Tool Guide for instructions on using this tool.
Diseases for 15-PGDH/HPGD Antibody (NB200-179F)
Discover more about diseases related to 15-PGDH/HPGD Antibody (NB200-179F).
| | Pathways for 15-PGDH/HPGD Antibody (NB200-179F)
View related products by pathway.
|
PTMs for 15-PGDH/HPGD Antibody (NB200-179F)
Learn more about PTMs related to 15-PGDH/HPGD Antibody (NB200-179F).
| | Research Areas for 15-PGDH/HPGD Antibody (NB200-179F)
Find related products by research area.
|
Blogs on 15-PGDH/HPGD