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Sterol Homeostasis Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Sterol Homeostasis Pathway and Atherosclerosis, Niemann-pick Diseases, Hypercholesterolemia, Inflammation, Alzheimer's Disease. The study of the Sterol Homeostasis Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Sterol Homeostasis Pathway has been researched in relation to Transport, Cholesterol Homeostasis, Secretion, Cholesterol Efflux, Localization. The Sterol Homeostasis Pathway complements our catalog of research reagents including antibodies and ELISA kits against LXR, STEROL REGULATORY ELEMENT BINDING PROTEIN 2, ABCA1, CRP, CYP7A1.

Sterol Homeostasis Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Sterol Homeostasis below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1064 products for the study of the Sterol Homeostasis Pathway that can be applied to Flow Cytometry, Western Blot, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.

NB400-105
Western Blot: ABCA1 Antibody [NB400-105] - Western Blot analysis of ABCA1 in total cell lysates of RAW264.9 cells treated with vehicle (-) or 9-cisretinoic acid and 22Rhydroxycholesterol (+). Samples used for this testing were 40 ug of total cell post-nuclear lysate from each group.Western Blot: ABCA1 Antibody [NB400-105] - Detection of ABCA1 in mouse peritoneal macrophages using NB 400-105 (Lot L). ECL exposure, 1 min. Lane 4: T09 uninduced lysate Lane 5: T09 induced lysate.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ChIP

269 Publications
NB400-148
Knockout Validated: Niemann-Pick C1 Antibody [NB400-148] - Western blot shows lysates of HeLa human cervical epithelial carcinoma parental cell line and NPC1 knockout (KO) HeLa cell line. PVDF membrane was probed with 1:1000 of Rabbit Anti-Human NPC1 Polyclonal Antibody (Catalog # NB400-148) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog #HAF008). Specific band was detected for NPC1 at approximately 240-260 kDa (as indicated) in the parental HeLa cell line, but is not detectable in the knockout HeLa cell line. This experiment was conducted under reducing conditions.Western Blot: Niemann-Pick C1 Antibody [NB400-148] - Hela lysate, BHK lysate, A431 lysate tested at 1:1000. Image provided by verified customer review.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, EM, ICC/IF

33 Publications
NBP2-00935
Western Blot: OSBP1 Antibody (1F2) [NBP2-00935] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OSBP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OSBP1.Immunocytochemistry/Immunofluorescence: OSBP1 Antibody (1F2) [NBP2-00935] Staining of COS7 cells transiently transfected by pCMV6-ENTRY OSBP1.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

NB400-132
Western Blot: ABCG1 Antibody [NB400-132] - Detection of ABCG1 in mouse peritoneal macrophages. Ln1: untreated mouse peritoneal macrophages, Ln2: 22-(R)-hydrocholesterol treated macrophages, Ln3: T0901713 treated macrophages, and Ln4: T091713 treated macrophages.Immunohistochemistry-Paraffin: ABCG1 Antibody [NB400-132] - Staining of human lung, alveolar macrophages.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

107 Publications
NBP1-78159
Western Blot: LDL R Antibody (C7) [NBP1-78159] - Total protein from human HeLa and HepG2 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 0.5 ug/ml anti-LDL receptor in 1% non-fat milk in TBST and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: LDL R Antibody (C7) [NBP1-78159] -  Image from a customer review on porcine intestinal epithelial cells IPEC-J2.

Mouse Monoclonal
Species Human, Rat, Porcine
Applications WB, EM, ELISA

17 Publications
NBP2-58327
Western Blot: ABCB6 Antibody [NBP2-58327] - Western blot analysis in human cell line RT-4 and human cell line U-251 MG.Immunocytochemistry/Immunofluorescence: ABCB6 Antibody [NBP2-58327] - Staining of human cell line U-251 MG shows localization to nucleoplasm & the Golgi apparatus.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NB600-582
Western Blot: SREBP1 Antibody (2A4) [NB600-582] - Western blot analysis of whole cell lysate from HeLa cells showing a single specific band for the expression of SREBP1 precursor protein (~120 kDa). Simple Western: SREBP1 Antibody (2A4) [NB600-582] - Simple Western lane view shows a specific band for SREBP1 in 1.0 mg/ml of HeLa lysate.  This experiment was performed under reducing conditions using the 12-230 kDa separation system.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

27 Publications
NBP2-36776
Western Blot: hnRNP C1 + C2 Antibody (CL2593) [NBP2-36776] - Analysis in U-251MG cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-HNRNPC antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.Immunocytochemistry/Immunofluorescence: hnRNP C1 + C2 Antibody (CL2593) [NBP2-36776] - Staining in U2OS cell line with Anti-HNRNPC monoclonal antibody, showing distinct nuclear (without nucleoli) staining in green. Microtubule- and nuclear probes are visualized in red and blue respectively (where available). Antibody staining is shown in green.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-84813
Immunohistochemistry-Paraffin: Kv11.3 Antibody [NBP1-84813] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP2-55973
Western Blot: SC5DL Antibody [NBP2-55973] - Western blot analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.Immunocytochemistry/Immunofluorescence: SC5DL Antibody [NBP2-55973] - Staining of human cell line HaCaT shows localization to nucleus, cytosol & endoplasmic reticulum. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP1-54446
Western Blot: SREBP2 Antibody (1D2) [NBP1-54446] - Lane1: HEp-2 cells. Lane 2: MCF-7 cells. Lane 3: LNCaP cells. Lane 4: HT1080 cells. Lane5 ZR75-1 cells.Immunocytochemistry/Immunofluorescence: SREBP2 Antibody (1D2) [NBP1-54446] - SREBP2 (1D2) antibody was tested in HeLa cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Mouse Monoclonal
Species Human, Chicken
Applications WB, ELISA, GS

14 Publications
NBP2-55690
Western Blot: CNBP Antibody [NBP2-55690] - Western blot analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.Immunocytochemistry/Immunofluorescence: CNBP Antibody [NBP2-55690] - Staining of human cell line SH-SY5Y shows localization to nucleus & cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

H00081033-P01
SDS-Page: Recombinant Human Kv11.2 Protein [H00081033-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human

NBP1-31824
Western Blot: ABCB11 Antibody [NBP1-31824] - Sample (30 ug of whole cell lysate) A: JurKat 5% SDS PAGE; antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: ABCB11 Antibody [NBP1-31824] - Sample: A431 cells were fixed in iced-cold MeOH for 5 min. Green: ABCB11 protein stained by BSEP antibody, Internal diluted at 1:500. Blue: Hoechst 33343 staining.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

MAB9120
    CYP7A1  was detected in immersion fixed human hepatocytes induced with dexamethasone  for 48 hours using Mouse Anti-Human CYP7A1 Polyclonal Antibody (Catalog #  MAB9120) at 10 µg/mL for 3 hours at room temperature.  Cells were stained using the NorthernLights™ 557-conjugated  Anti-Mouse IgG Secondary Antibody (red; Catalog # <a class=

Mouse Monoclonal
Species Human
Applications ICC

210-TA
Recombinant Human TNF-alpha  (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.1 µg/lane of Recombinant Human TNF-alpha  was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.


Species Human

     19 Reviews

516 Publications
NBP1-97507
Western Blot: HO-1/HMOX1/HSP32 Antibody (HO-1-1) [NBP1-97507] -  Lane 1: MW marker; Lane 2: HO-1 (rat), (recombinant); Lane 3: HO-1 (human), (recombinant); Lane 4: HO-2 (human), (recombinant); Lane 5: MDBK cell lysate; Lane 6: Dog liver microsome; Lane 7: Mouse liver microsome.Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (HO-1-1) [NBP1-97507] - Analysis of human spleen tissue stained with HO-1, mAb (HO-1-1) at 10ug/ml.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

7 Publications