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Response To Insulin Stimulus Pathway Bioinformatics

Insulin is a peptide hormone that is responsible for helping with the regulation of carbohydrate and fat metabolism, as it causes the cells of various tissues to absorb glucose in various forms from the bloodstream. An insulin stimulus causes both insulin and glucose to migrate to the cells that require energy, where the insulin then binds to an insulin receptor tyrosine kinase, which autophosphorylates and starts a multitude of cascades through different signaling molecules, which include Akt and PKB. The cascades can lead to functions such as cell growth, glucose and lipid homeostasis, apoptosis, and the influx of glucose into the cell, which occurs due to the movement of GLUT4 vesicles to the membrane, which creates a glucose transmembrane channel. Deficiencies in insulin or resistance to the protein can lead to glucose not being able to enter the cell, which can result in diseases including diabetes mellitus and polycystic ovary syndrome.

Response To Insulin Stimulus Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Response To Insulin Stimulus below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 831 products for the study of the Response To Insulin Stimulus Pathway that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

Immunohistochemistry-Paraffin: Insulin Antibody (2D11-H5) [NBP2-15195] - Analysisof Insulin in formalin-fixed paraffin embedded human pancreas using Insulin antibody (1:500), peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of cells.

Mouse Monoclonal
Species Human, Mouse
Applications Flow, ICC/IF, IHC-Fr

4 Publications
Western Blot: gamma-glutamyl hydrolase Antibody [NBP1-90927] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY418375)Immunohistochemistry-Paraffin: gamma-glutamyl hydrolase Antibody [NBP1-90927] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
Western Blot: Growth Hormone Antibody [NBP1-31408] - Sample(30 ug whole cell lysate) A:293T 12% SDS PAGE, antibody diluted at 1:1000.Immunohistochemistry-Paraffin: Growth Hormone Antibody [NBP1-31408] - Paraffin-embedded Placenta, using antibody 10 ug/ml.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

Western Blot: Adiponectin Antibody [NB100-65810] - Western blot analysis of Adoponectin in 1. human liver 2. rat liver 3. HL60Immunocytochemistry/Immunofluorescence: Adiponectin Antibody [NB100-65810] - Adiponectin antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Cytoplasmic, membrane and internal organelle staining was observed.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

6 Publications
SDS-Page: Rat IGF-I Protein [NBP2-35219]

Species Rat
Applications Func, PAGE

Related Genes

The Response To Insulin Stimulus Pathway has been researched against:

Related Pathways

The Response To Insulin Stimulus Pathway has been linked to:

Related PTMs