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Regulation Of Neurogenesis Pathway Bioinformatics

Neurogenesis is the generation of neurons from stem and progenitor cells. The majority of neurogenesis occurs in pre-natal development, but recent research has found neurogeneration to occur in adults in two regions of the brain: the subventricular zone of the lateral ventricles, which ultimately lead to the olfactory bulb, and the subgranular zone of the dentate gyrus located in the hippocampus. The majority of these new neurons die quickly after generation, but some are able to migrate into the surrounding brain tissue. The rate of successful neurogenesis depends on several factors including testosterone and acetylcholine, exercise, CNS injuries, and chronic stress. There are also other biological factors that are involved in the regulation of neurogenesis, including dopamine, the FGF receptor-inhibiting PACAP, and the epigenetic regulation pathway. Neurogenesis has been shown to have a positive effect on memory retention and capacity as well as on the side effects of stress.

Regulation Of Neurogenesis Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Regulation Of Neurogenesis below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 1460 products for the study of the Regulation Of Neurogenesis Pathway that can be applied to Flow Cytometry, Western Blot, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.

Western Blot: GFAP Antibody [NB300-141] - Analysis of GFAP expression in whole rat cerebellum homogenate.Immunocytochemistry/Immunofluorescence: GFAP Antibody [NB300-141] - Cultured Rat Hippocampal Neuron, image courtesy of customer.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     3 Reviews

32 Publications
Western blot shows lysates of A431 human epithelial carcinoma cell line untreated<BR>(‑) or treated (+) with 100 μM pervanadate (PV) for 10 minutes. PVDF membrane was probed with 0.2 µg/mL of Rabbit Anti-Human Phospho-EGF R/ErbB1 (Y1173) Antigen Affinity-purified Polyclonal Antibody, followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # <A class=NoLineLink href=EGF R/ErbB1 phosphorylated at Y1173 was detected in immersion fixed A431 human epithelial carcinoma cell line untreated (lower panel) or treated (upper panel) with pervanadate using Rabbit Anti-Human Phospho-EGF R/ErbB1 (Y1173) Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1095) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rabbit IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, IHC

5 Publications
Western Blot: Niemann-Pick C1 Antibody [NB400-148] - Hela lysate, BHK lysate, A431 lysate tested at 1:1000. Image provided by verified customer review.Immunocytochemistry/Immunofluorescence: Niemann-Pick C1 Antibody [NB400-148] - NPC1 antibody was tested in HeLa cells with Dylight 488 (green). Nuclei were counterstained with Dapi (blue).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, EM, ICC/IF

     3 Reviews

33 Publications
Western Blot: Presenilin-1 Antibody (APS 11) [NB300-749] - Analysis of 25 ug of SH-SY5Y (lane 1), human brain (lane 2) and mouse brain (lane 3).Immunocytochemistry/Immunofluorescence: Presenilin-1 Antibody (APS 11) [NB300-749] - Mouse fibroblasts.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

     1 Review

1 Publication
Western Blot: Neurogenin-1 Antibody (3F9) [NBP1-47871] -  Analysis of extracts (35ug) from 9 different cell lines by using anti-Neurogenin 1 monoclonal antibody.Immunocytochemistry/Immunofluorescence: Neurogenin-1 Antibody (3F9) [NBP1-47871] - Staining of COS7 cells.

Mouse Monoclonal
Species Human, Monkey, Primate
Applications WB, ICC/IF, IHC

Western blot shows lysates of mouse kidney tissue. PVDF Membrane was probed with 1 µg/mL of Human PACAP/ADCYAP1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6380) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=

Sheep Polyclonal
Species Mouse
Applications WB

Immunohistochemistry: Nestin Antibody [NB100-1604] - A tissue section through an e 13 mouse brain showing Nestin (green staining) in neural stem cells of the ventricular zone of the CNS. DAPI (blue staining) allows visualization of nuclei.  The fixative was 2% paraformaldehyde in PBS, and the tissue was emersed in this fixative for 30 minutes at room temperature.Immunohistochemistry-Frozen: Nestin Antibody [NB100-1604] - Analysis of Nestin in frozen mouse tissue using anti-Nestin antibody. Image from verified customer review.

Chicken Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     2 Reviews

28 Publications
Western Blot: Doublecortin Antibody (3E1) [NBP1-92684] - Western blot of crude rat brain extract from a postnatal 3 day animal stained with NBP1-92684. Two bands at ~45kDa and ~35kDa show that NBP1-92684 binds to an epitope in the region of Doublecortin shared by Lis-A, and Lis-B, Lis-C and Lis-D, the C terminal 360 amino acids of Lis-A.Immunocytochemistry/Immunofluorescence: Doublecortin Antibody (3E1) [NBP1-92684] - Rat brain neural cultures stained with NBP1-92684 (green), a chicken polyclonal antibody to GFAP (NB300-213, red) and DNA (blue). The NBP1-92684 antibody reveals strong cytoplasmic staining in a population of small developing neurons. These cells are often found in small clumps as in these cultures, as in this example. Note that they are not positive for MAP2, which is characteristic of more mature neurons, and that the mature neuron shown is negative for NBP1-92684. This Doublecortin antibody is therefore an excellent marker of developing neuronal cells.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

Western Blot: GCNF/NR6A1 Antibody (4G8) [NBP2-37467] - Western blot analysis using NR6A1 mouse mAb against K562 (1), NTERA-2 (2), HEK293 (3), HUVE-12 (4), and HeLa (5) cell lysate.Immunocytochemistry/Immunofluorescence: GCNF/NR6A1 Antibody (4G8) [NBP2-37467] - Immunofluorescence analysis of HepG2 cells using NR6A1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow


Mouse Monoclonal
Species Human
Applications WB, IHC, IP

4 Publications
Western Blot: Notch-1 Antibody (mN1A) [NB100-78486] - Cell extracts from Jurkat (Lane 1) or mouse thymocytes (Lane 2) were Western Blot analyzed with monoclonal anti-NOTCH1 antibody. The mN1A antibody recognizes both mouse and human 270 kD full-length NOTCH1 and 110-120 kD cleaved NOTCH 1 (NICD).Immunocytochemistry/Immunofluorescence: Notch-1 Antibody (mN1A) [NB100-78486] -  The Notch1 Antibody was tested in HEK293 cells at a 1:50 dilution against Dylight 488 (Green).  Actin was counterstained against Phalloidin 568 (Red) and cells were mounted in DAPI Flouromount (Blue).

Mouse Monoclonal
Species Human, Mouse, Rat (Negative)
Applications WB, Flow, ICC/IF

     1 Review

5 Publications