Pronuclear fusion is the final step of the sperm and egg cells coming together to produce a fertilized zygote. The egg and sperm both contain haploid pronuclei, and when the sperm is enclosed by the egg cell, the two pronuclei begin to migrate towards each other with the help of microtubules that extend from the sperm’s centrosome. The microtubules attach to the female pronucleus and are pulled toward the male pronucleus with the help of motor dynein. Because of this, pronuclear migration can be inhibited with the use of microtubule depolymerizing drugs, as shown by experiments with colcemid.
Pronuclear Migration Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Pronuclear Migration below!
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We have 692 products for the study of the Pronuclear Migration Pathway that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.