Programmed Necrotic Cell Death Pathway Bioinformatics
Necrosis is a form a premature cell death that has been shown to occur in processes including tissue renewal and embryogenesis. This form of cell death has also been seen in immune responses, as primary T-lymphocytes and other factors involved in this function are caspase-independent and are morphologically necrotic. The mechanism by which necrotic cell death occurs begins with the activation of receptors by proteins such as NLRP3 that cause the cell to swell until the membrane loses its integrity, which results in the cellular material being deposited into the extracellular space. This initiates an inflammatory response and the buildup of dead tissues around the site of the cell death. There are five kinds of buildup, coagulative (a buildup of gel), liquefactive (a buildup of liquid), caseous (a buildup of gel and liquid), fat (resulting from the necrosis of fat tissue), and fibrinoid (the result of vascular damage).
Programmed Necrotic Cell Death Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Programmed Necrotic Cell Death below!
For more information on how to use Laverne, please read the How to Guide.
We have 705 products for the study of the Programmed Necrotic Cell Death Pathway that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.