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Pigmentation Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Pigmentation Pathway and Pigmentation Disorders, Melanoma, Neoplasms, Skin Neoplasms, Malignant Neoplasms. The study of the Pigmentation Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Pigmentation Pathway has been researched in relation to Pathogenesis, Aging, Transport, Localization, Secretion. The Pigmentation Pathway complements our catalog of research reagents including antibodies and ELISA kits against TYR, POMC, MITF, TYRP1, MC1R.

Pigmentation Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Pigmentation below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1211 products for the study of the Pigmentation Pathway that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-67233
Western Blot: Tyrosinase Antibody (C2-B5) [NBP2-67233] - Analysis of tyrosinase on melanoma cells lysate using anti- tyrosinase antibody at 1/1,000 dilution.Immunocytochemistry/Immunofluorescence: Tyrosinase Antibody (C2-B5) [NBP2-67233] - Staining tyrosinase in B16F1 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

NB100-1533
Western Blot: POMC Antibody [NB100-1533] - Staining of NIH3T3 cell lysate (35 ug protein in RIPA buffer). Antibody at 0.3 ug/mL. Detected by chemiluminescence.Immunohistochemistry-Paraffin: POMC Antibody [NB100-1533] - Staining of paraffin embedded Human Pituitary Gland. Antibody at 2 ug/mL. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

9 Publications
NB100-56561
Western Blot: MITF Antibody (21D1418) [NB100-56561] - Analysis of A375 lysate using MITF antibody at 4 ug/ml.Western Blot: MITF Antibody (21D1418) [NB100-56561] - Analysis of HeLa lysate (35ug per lane, RIPA buffer) using MiTF antibody (NB100-56561) at 0.1ug/ml. Band detected at ~60kDa. (Expected MW of 58.2kDa according to NP_937802.1).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB

1 Publication
NBP1-88370
Western Blot: TYRP1 Antibody [NBP1-88370] - Analysis in control (vector only transfected HEK293T lysate) and TYRP1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunocytochemistry/Immunofluorescence: TYRP1 Antibody [NBP1-88370] - Staining of human cell line SK-MEL-30 shows localization to vesicles. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NLS1040
Immunohistochemistry-Paraffin: Melanocortin-1 R/MC1R Antibody [NLS1040] - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)Immunohistochemistry-Paraffin: Melanocortin-1 R/MC1R Antibody [NLS1040] - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Rabbit Polyclonal
Species Human, Monkey
Applications IHC, IHC-P

     1 Review

664-LI/CF
<p align=<P align=left>Recombinant Human LIGHT/TNFSF14 (Catalog # 664-LI/CF) stimulates cell proliferation in HUVEC human umbilical vein endothelial cells. The ED<SUB>50</SUB> is 1-4 ng/mL.</P>


Species Human

14 Publications
NBP1-86892
Western Blot: TRP2 Antibody [NBP1-86892] - Analysis in control (vector only transfected HEK293T lysate) and DCT over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: TRP2 Antibody [NBP1-86892] - Staining of human testis.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
7466-SC/CF


Species Human

2 Publications
NBP2-20486
Western Blot: SS18L1 Antibody [NBP2-20486] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SS18L1 Antibody [NBP2-20486] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

NBP1-56853
Western Blot: RPE Antibody [NBP1-56853] - Human Muscle lysate, concentration 0.2-1 ug/ml.Immunocytochemistry/Immunofluorescence: RPE Antibody [NBP1-56853] - Antibody  0 Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver  Observed Staining: Cytoplasm but only in connective tissue cells in the interlobular septum, very low tissue distribution Primary Antibody

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-14835
Western Blot: LKB1 Antibody [NBP2-14835] - LKB1 antibody was tested in human testes lysate.Immunocytochemistry/Immunofluorescence: LKB1 Antibody [NBP2-14835] - LKB1 antibody was tested in HepG2 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
NBP1-60052
Western Blot: OCA2 Antibody [NBP1-60052] - Human Placenta lysate, concentration 0.2-1 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB

9094-AG
Recombinant Human ASIP/Agouti (Catalog # 9094-AG) inhibits alpha-MSH induced eumelanin production in B16F1 mouse melanoma cells. The ED<sub>50</sub> for this effect is 0.8-4 μg/mL.


Species Human

NBP2-34638
Flow Cytometry: PMEL17/SILV Antibody (HMB45) - Azide and BSA Free [NBP2-34638] - An intracellular stain was performed on SK-MEL-28 cells with PMEL17/SILV Antibody [HMB45] NBP2-34638B (blue) and a matched isotype control (orange). Both antibodies were conjugated to Biotin. Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature, followed by Streptavidin - R-Phycoerythrin Protein (2012-1000, Novus Biologicals).Flow Cytometry: PMEL17/SILV Antibody (HMB45) - Azide and BSA Free [NBP2-34638] - An intracellular stain was performed on SK-MEL-28 cells with PMEL17/SILV Antibody (HMB45) NBP2-34638PCP (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to PerCP.

Mouse Monoclonal
Species Human, Canine (Negative), Rat (Negative)
Applications WB, ELISA, Flow

AF1356
Western blot shows lysates of MO7e human megakaryocytic leukemic cell line, P815 mouse mastocytoma cell line, and MC/9‑2 mouse mast cell line. PVDF membrane was probed with 0.1 µg/mL of Goat Anti-Human/Mouse CD117/c-kit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1356) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=CD117/c-kit was detected in immersion fixed frozen sections of mouse embryo using Goat Anti-Human/Mouse CD117/c-kit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1356) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Goat Polyclonal
Species Human, Mouse
Applications WB, Simple Western, Flow

     9 Reviews

29 Publications
NBP1-84307
Western Blot: Calcium Channel Flower Homolog Antibody [NBP1-84307] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY413631)Immunocytochemistry/Immunofluorescence: Calcium Channel Flower Homolog Antibody [NBP1-84307] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP1-59786
Western Blot: SLC45A2 Antibody [NBP1-59786] - Human Fetal Liver, Antibody Dilution: 1.0 ug/ml.Western Blot: SLC45A2 Antibody [NBP1-59786] - Titration: 0.2-1 ug/ml Positive Control: Jurkat cell lysate.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB

NBP1-85445
Western Blot: MSX2 Antibody [NBP1-85445] - Analysis in Caco-2 cells transfected with control siRNA, target specific siRNA probe #1, using Anti-MSX2 antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.Immunohistochemistry-Paraffin: MSX2 Antibody [NBP1-85445] - Staining of human placenta shows strong nuclear positivity in trophoblastic cells.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

3 Publications