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Pancreas Development Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Pancreas Development Pathway and Diabetes Mellitus, Diabetes Mellitus, Non-insulin-dependent, Diabetes Mellitus, Insulin-dependent, Malignant Neoplasms, Impaired Glucose Tolerance. The study of the Pancreas Development Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Pancreas Development Pathway has been researched in relation to Cell Differentiation, Secretion, Insulin Secretion, Endocrine Pancreas Development, Regeneration. The Pancreas Development Pathway complements our catalog of research reagents including antibodies and ELISA kits against PDX1, INS, NEUROG3, PDHX, PTF1A.

Pancreas Development Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Pancreas Development below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1781 products for the study of the Pancreas Development Pathway that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NB100-60953
Western Blot: PTF1A Antibody [NB100-60953] - Staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Antibody at 0.5 ug/mL. Detected by chemiluminescence.Western Blot: PTF1A Antibody [NB100-60953] - Staining at 1 ug/mL antibody of U2OS (A) + peptide (B), 0.5ug/ml antibody Jurkat (C) + peptide (D) and NIH3T3 (E) + peptide (F) cell lysate (35 ug protein in RIPA buffer). Detected by chemiluminescence.

Goat Polyclonal
Species Human, Mouse
Applications WB, PEP-ELISA

2 Publications
NB300-750
Western Blot: Pax6 Antibody [NB300-750] - Analysis of sheep retinal extractImmunocytochemistry/Immunofluorescence: Pax6 Antibody [NB300-750] - ARPE-19 monolayer on glass substrate. Fixative Methanol Blocking Goat Serum. Dilution 1:100. Incubation 1h @ RT. This image was submitted via customer Review.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     4 Reviews

5 Publications
NBP1-49672
Western Blot: NKX6.1 Antibody [NBP1-49672] - Analysis of Nkx6.1 in human skeletal muscle.Immunocytochemistry/Immunofluorescence: NKX6.1 Antibody [NBP1-49672] - Nkx6.1 antibody was tested at 1:250 in INS-1 cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and DyLight 550 (red). Image objective 40X.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     4 Reviews

13 Publications
NBP1-82554
Western Blot: NKX2.2 Antibody [NBP1-82554] - Analysis in human cell line U-138 MG.Immunohistochemistry-Paraffin: NKX2.2 Antibody [NBP1-82554] - Staining of human cerebellum shows moderate postivity in cells in molecular layer.

Rabbit Polyclonal
Species Human, Mouse, Feline
Applications WB, ICC/IF, IHC

     2 Reviews

5 Publications
NBP1-84079
Western Blot: PDHX Antibody [NBP1-84079] - Analysis using Anti-PDHX antibody NBP1-84079 (A) shows similar pattern to independent antibody NBP1-84080 (B).Immunohistochemistry-Paraffin: PDHX Antibody [NBP1-84079] - Staining of human kidney.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-24691
Immunocytochemistry/Immunofluorescence: MNX1/HLXB9 Antibody [NBP2-24691] - MCF7 cells were fixed in 4% paraformaldehyde for 10 minutes and permeabilized in 0.05% Triton X-100 in PBS for 5 minutes. The cells were incubated with anti-MNX1/HLXB9 NBP2-24691 at 1 ug/ml for 60 minutes at room temperature and detected with an anti-rabbit Dylight 488 (Green) at a 1:1000 dilution for 60 minutes. Nuclei were counterstained with DAPI (Blue).  Cells were imaged using a 100X objective and digitally deconvolved.Immunocytochemistry/Immunofluorescence: MNX1/HLXB9 Antibody [NBP2-24691] - Neuro2a cells were fixed in 4% paraformaldehyde for 10 minutes and permeabilized in 0.05% Triton X-100 in PBS for 5 minutes. The cells were incubated with anti-MNX1/HLXB9 NBP2-24691 at 1 ug/ml for 60 minutes at room temperature and detected with an anti-rabbit Dylight 488 (Green) at a 1:1000 dilution for 60 minutes. Nuclei were counterstained with DAPI (Blue).  Cells were imaged using a 100X objective and digitally deconvolved.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
NBP2-27079
Western Blot: HNF-6/ONECUT1 Antibody [NBP2-27079] - Analysis ofHNF6 inhuman pancreas in the 1) absence and 2) presence of immunizing peptide, and 3) rat pancreasusing this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.Immunohistochemistry-Paraffin: HNF-6/ONECUT1 Antibody [NBP2-27079] -  Analysis of HNF6 in formalin-fixed, paraffin-embedded human liver tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.

Rabbit Polyclonal
Species Human, Canine, Primate
Applications WB, IHC, IHC-P

AF1837
    Western  blot shows lysates of JOY6 human induced pluripotent stem cells  undifferentiated and differentiatied into motor neurons. PVDF membrane was  probed with 1 µg/mL of Goat Anti-Human Islet‑1 Antigen  Affinity-purified Polyclonal Antibody (Catalog # AF1837) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=Islet‑1 was detected in immersion fixed iPS2 human induced pluripotent stem cells differentiated to endocrine progenitor cells using Goat Anti-Human Islet‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1837) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Simple Western, IHC

16 Publications
AF2400
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, Jurkat human acute T cell leukemia cell line, and K562 human chronic myelogenous leukemia cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human HNF‑3 beta /FoxA2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2400) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Mouse splenocytes were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. HNF‑3 beta /FoxA2/DNA complexes were immunoprecipitated using 5 μg Goat Anti-Human HNF‑3 beta /FoxA2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2400) or control antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, IHC, ChIP

56 Publications
AF2419
Western blot shows lysates of  beta TC‑6 mouse beta cell insulinoma cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human PDX‑1/IPF1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2419) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Simple Western lane view shows lysates of  beta TC‑6 mouse beta cell insulinoma cell line, loaded at 0.2 mg/mL. A specific band was detected for PDX‑1/IPF1 at approximately 48 kDa (as indicated) using 10 µg/mL of Goat Anti-Human PDX‑1/IPF1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2419) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, Simple Western, IHC

37 Publications
AF2614

Goat Polyclonal
Species Human
Applications WB, ICC

2 Publications
AF2746
Neurogenic Differentiation factor 1 (NeuroD1) was detected in immersion fixed  beta TC-6 mouse beta cell insulinoma cell line using Human/Mouse NeuroD1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2746) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human, Mouse
Applications WB, ICC

7 Publications
AF3444
Western blot shows lysates of human placenta and prostate tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human Neurogenin‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3444) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Neurogenin‑3 was detected in immersion fixed paraffin-embedded sections of human placenta using Sheep Anti-Human Neurogenin‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3444) at 1 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Sheep IgG VisUCyte™ HRP Polymer Antibody (<a class=

Sheep Polyclonal
Species Human
Applications WB, IHC

10 Publications
MAB1417
Insulin was detected in immersion fixed  beta TC‑6 mouse beta cell insulinoma cell line using Human/Mouse/Bovine Insulin Monoclonal Antibody (Catalog # MAB1417) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=Insulin was detected in immersion fixed paraffin-embedded sections of human pancreas using Rat Anti-Human/Mouse/Bovine Insulin Monoclonal Antibody (Catalog # MAB1417) at 0.5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rat IgG VisUCyte™ HRP Polymer Antibody (<a class=

Rat Monoclonal
Species Human, Mouse, Bovine
Applications IHC, CyTOF-ready, ICC

16 Publications
MAB1249
Glucagon was detected in immersion fixed beta TC-6 mouse beta cell insulinoma cell line using 10 µg/mL Human/Mouse Glucagon Monoclonal Antibody (Catalog # MAB1249) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <A class=     beta TC‑6  mouse beta cell insulinoma cell line was stained with Mouse Anti-Human/Mouse  Glucagon Monoclonal Antibody (Catalog # MAB1249, filled histogram) or isotype  control antibody (Catalog # <a class=

Mouse Monoclonal
Species Human, Mouse
Applications CyTOF-ready, ICC, ICFlow

     1 Review

8 Publications
NBP2-37447
Western Blot: Somatostatin Antibody (7G5) [NBP2-37447] - Analysis using SST mAb against human SST recombinant protein. (Expected MW is 38.2 kDa)Immunohistochemistry-Paraffin: Somatostatin Antibody (7G5) [NBP2-37447] - Analysis of lung cancer tissues using SST mouse mAb with DAB staining.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

     1 Review

2 Publications
345-FG/CF
Recombinant Human FGF-10 (Catalog # 345-FG/CF) stimulates cell proliferation of the 4MBr‑5 rhesus monkey epithelial cell line. The ED<SUB>50</SUB> for this effect is 20‑100 ng/mL. 1 μg/lane of Recombinant Human FGF-10 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 21 kDa.


Species Human
Applications BA

84 Publications
1845-SH/CF
Recombinant Human Sonic Hedgehog/Shh (C24II), N-Terminus (Catalog #<br>1845-SH/CF) induces alkaline phosphatase production by the C3H10T1/2 mouse embryonic fibroblast cell line. The ED<sub>50</sub> for this effect is 0.1‑0.4 μg/mL.1 μg/lane of Recombinant Human Sonic Hedgehog/Shh (C24II), N-Terminus was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 22 kDa.


Species Human
Applications BA

57 Publications