Nuclear pore complexes (NPCs) are tiny holes in the nuclear envelope that allow for material to pass into and out of the nucleus. NPC assembly must occur both at the end of mitosis as well as when the nucleus and nuclear envelope expand during metabolic cell growth. The distribution of the NPCs has been shown to be uneven over the surface of the nuclear membrane, but has also been shown to be nonrandom. Certain events can occur that lead to further changes in distribution, such as fragmentation of the NPC aggregates, spermiogenesis, and apoptosis. The protein complex Nup133p can, however, help to redistribute the NPCs to a more homologous manner via lateral movements along the nuclear envelope.
Nuclear Pore Distribution Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Nuclear Pore Distribution below!
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We have 336 products for the study of the Nuclear Pore Distribution Pathway that can be applied to Chromatin Immunoprecipitation, Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.