Nuclear mRNA surveillance is the act of quality checking the mRNA as it goes through its processes that leads to transcription and the generation of new cells. The pre-mRNA must go through a series of events before it can become a complete transcript, and there is crosstalk, or surveillance, which ensures the mRNA is not defective and can be further utilized by the cell. The nuclear exosome, major nuclear decay machinery, and an Rrp6p-specific complex are the factors that contribute to the determination of the fate of the mRNA. If the mRNA is viewed as defective, events can be triggered such as nuclear deadenylation and exosome-mediated degradation. If not, it will be further processed and transported to the cytoplasm for its continuation in the function of the cell cycle.
Nuclear Mrna Surveillance Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Nuclear Mrna Surveillance below!
For more information on how to use Laverne, please read the How to Guide.
We have 231 products for the study of the Nuclear Mrna Surveillance Pathway that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.