Nuclear migration is a phenomenon that occurs in neurons during brain development. Movement of the nucleus occurs during the proliferative and post-mitotic phases of development, and there are three separate kinds of movement of the nucleus. Interkinetic nuclear migration is when the nucleus moves back and forth between the apical and basal sides of the cell depending on its necessary location in the cell cycle. Proliferative nuclear migration is when the nucleus begins on the apical side of the cell, and transfers to the basal side after the M-phase for the remainder of the cell cycle. The nucleus can also help with cellular migration, in a method called nuclear translocation. Microtubules from the cytoskeleton surround the nucleus, and with the help of certain proteins, physically move the nucleus, which in turns signals the cell to begin its migration.
Nuclear Migration Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Nuclear Migration below!
For more information on how to use Laverne, please read the How to Guide.
We have 1949 products for the study of the Nuclear Migration Pathway that can be applied to Chromatin Immunoprecipitation, Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.