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Nuclear Migration Pathway Bioinformatics

Nuclear migration is a phenomenon that occurs in neurons during brain development. Movement of the nucleus occurs during the proliferative and post-mitotic phases of development, and there are three separate kinds of movement of the nucleus. Interkinetic nuclear migration is when the nucleus moves back and forth between the apical and basal sides of the cell depending on its necessary location in the cell cycle. Proliferative nuclear migration is when the nucleus begins on the apical side of the cell, and transfers to the basal side after the M-phase for the remainder of the cell cycle. The nucleus can also help with cellular migration, in a method called nuclear translocation. Microtubules from the cytoskeleton surround the nucleus, and with the help of certain proteins, physically move the nucleus, which in turns signals the cell to begin its migration.

Nuclear Migration Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Nuclear Migration below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1342 products for the study of the Nuclear Migration Pathway that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Western Blot, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP), Immunocytochemistry/Immunofluorescence from our catalog of antibodies and ELISA kits.

NBP1-87769
Western Blot: LIS1 Antibody [NBP1-87769] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: LIS1 Antibody [NBP1-87769] - Immunofluorescent staining of human cell line U-251 MG shows localization to centrosome.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     2 Reviews

NBP1-89517
Western Blot: NUDC Antibody [NBP1-89517] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).Immunocytochemistry/Immunofluorescence: NUDC Antibody [NBP1-89517] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Publication
AF1016
<P align=left>Recombinant Human Thrombopoietin/Tpo (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, Neut

1 Publication
210-TA
Recombinant Human TNF-alpha  (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.1 µg/lane of Recombinant Human TNF-alpha  was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.


Species Human

     19 Reviews

511 Publications
NBP2-22203
Western Blot: ERK1 Antibody (1E5) [NBP2-22203] - Western blot analysis of whole cell lysates from (1) MCF7 (2) NIH3T3 cell lines using ERK1 antibody (clone 1E5) at 1:1000 dilution. The signal was developed using HRP labeled goat-anti Mouse secondary antibody with ECL based detection. Immunocytochemistry/Immunofluorescence: ERK1 Antibody (1E5) [NBP2-22203] - Analysis of NIH/3T3 cells using ERK1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, Flow

NB100-56583
Western Blot: NFkB p105/p50 Antibody (2J10D7) [NB100-56583] - analysis of p50 in HeLa lysate in the A) absence and B) presence of immunizing peptide using p50 antibody at 5 ug/ml.Immunohistochemistry-Paraffin: NFkB p105/p50 Antibody (2J10D7) [NB100-56583] - analysis of human breast tumor tissue using an isotype control antibody (top) and p50 antibody (bottom) at 5 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, Flow, IHC-P

     1 Review

1 Publication
NB500-106
Western Blot: PCNA Antibody (PC10) [NB500-106] - Whole cell protein from human HeLa, A431, mouse Neuro2A and rat PC12 cells was separated on a 4-20% gel by SDS-PAGE, transferred to 0.2 um PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 1.0 ug/ml anti-Histone h3 in block buffer and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: PCNA Antibody (PC10) [NB500-106] - HeLa cells were fixed and permeabilized for 10 minutes using -20C MeOH. The cells were incubated with anti-PCNA [PC10] at 5 ug/ml overnight at 4C and detected with an anti-mouse IgG Dylight 488 (Green) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ChIP

     4 Reviews

23 Publications
NBP2-14306
Western Blot: ARFRP1 Antibody [NBP2-14306] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: ARFRP1 Antibody [NBP2-14306] - Staining of human stomach, lower shows strong cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

MAB9167
Western Blot: Neutrophil Elastase/ELA2 Antibody (950334) [MAB9167] - Analysis of human bone marrow tissue lysate with 0.5 ug/ml of hELA-2 Monoclonal Antibody followed by HRP-conjugated Anti-Rabbit IgG Antibody. A specific band was detected for hELA-2 at approximately 25-30 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.Immunocytochemistry: Neutrophil Elastase/ELA2 Antibody (950334) - Azide Free [MAB9167] - Neutrophil Elastase/ELA2 was detected in immersion fixed THP-1 cell using Neutrophil Elastase/ELA2 Monoclonal Antibody at 8 ug/ml dilution. Cells were stained using Donkey anti-Mouse IgG Secondary Antibody [NL557] (red) and counterstained with DAPI (blue). Specific staining was localized to cytoplasmic.

Mouse Monoclonal
Species Human
Applications WB, Flow, IHC

     1 Review

288-TP
1 µg/lane of Recombinant Human Thrombopoietin was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing major bands at 43-60 kDa. Multiple bands in gel are due to variable glycosylation.Recombinant Human Thrombopoietin/Tpo (Catalog # 288-TP) stimulates proliferation in the MO7e human megakaryocytic leukemic cell line. The ED<SUB>50</SUB> for this effect is 0.3-3 ng/mL.


Species Human

50 Publications
NBP2-29463
Immunohistochemistry-Paraffin: p21/CIP1/CDKN1A Antibody (WA-1 (HJ21)) [NBP2-29463] - Formalin-fixed, paraffin-embedded human bladder carcinoma stained with p21 Monoclonal Antibody (WA-1).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

11 Publications
NBP2-15274
Western Blot: ACTR1A Antibody [NBP2-15274] - Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE, antibody diluted at 1:2000.Immunohistochemistry-Paraffin: ACTR1A Antibody [NBP2-15274] - Paraffin-embedded Lung ca, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

NBP2-59944
Western Blot: Nesprin 2 Antibody (6C11) [NBP2-59944] - HEK293 cells transiently expressing either GFP alone or GFP fused a small Nesp2 isoform (Nesp2a2DKASH) lacking the C-terminal KASH domain. This small isoform contains the ~180 residue Nesp2 polypeptide that was employed in the immunogen. Total cell lysates were analyzed by western blot employing either a rabbit anti-GFP or culture supernatant from three independent anti-Nesp2 hybridoma clones (6C11, 10H8 and 5C3)Immunocytochemistry/Immunofluorescence: Nesprin 2 Antibody (6C11) [NBP2-59944] - Immunofluorescence microscopy of HeLa cells. The antibodies can be used on either formaldehyde- or methanol-fixed cells.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF

NBP1-88848
Immunohistochemistry-Paraffin: APOBEC2 Antibody [NBP1-88848] - Staining of human prostate shows low expression as expected.Immunohistochemistry: APOBEC2 Antibody [NBP1-88848] - Staining of human skeletal muscle shows cytoplasmic immunoreactivity as well as a few positive nuclei in myocytes.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-89088
Immunohistochemistry-Paraffin: Angiopoietin-like Protein 1/ANGPTL1 Antibody [NBP1-89088] - Staining of human heart muscle shows strong cytoplasmic positivity in cardiomyocytes.Immunohistochemistry-Paraffin: Angiopoietin-like Protein 1/ANGPTL1 Antibody [NBP1-89088] - Staining in human placenta and lymph node tissues.. Corresponding ANGPTL1 RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

PP-H7147-00

Mouse Monoclonal
Species Human
Applications WB, IHC, IP

     2 Reviews

20 Publications
H00005308-M01
Immunocytochemistry/Immunofluorescence: PITX2 Antibody (2G6) [H00005308-M01] - Analysis of monoclonal antibody to PITX2 on HeLa cell. Antibody concentration 10 ug/ml.ELISA: PITX2 Antibody (2G6) [H00005308-M01] - Detection limit for recombinant GST tagged PITX2 is approximately 0.03ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

4 Publications