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Nuclear Migration Pathway Bioinformatics

Nuclear migration is a phenomenon that occurs in neurons during brain development. Movement of the nucleus occurs during the proliferative and post-mitotic phases of development, and there are three separate kinds of movement of the nucleus. Interkinetic nuclear migration is when the nucleus moves back and forth between the apical and basal sides of the cell depending on its necessary location in the cell cycle. Proliferative nuclear migration is when the nucleus begins on the apical side of the cell, and transfers to the basal side after the M-phase for the remainder of the cell cycle. The nucleus can also help with cellular migration, in a method called nuclear translocation. Microtubules from the cytoskeleton surround the nucleus, and with the help of certain proteins, physically move the nucleus, which in turns signals the cell to begin its migration.

Nuclear Migration Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Nuclear Migration below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1949 products for the study of the Nuclear Migration Pathway that can be applied to Chromatin Immunoprecipitation, Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NFkB p105/p50 Antibody (2J10D7) - BSA Free
NB100-56583
Western Blot: NFkB p105/p50 Antibody (2J10D7) [NB100-56583] - Analysis of p50 in HeLa lysate in the A) absence and B) presence of immunizing peptide using p50 antibody at 5 ug/ml.Immunohistochemistry-Paraffin: NFkB p105/p50 Antibody (2J10D7) [NB100-56583] - IHC-P of rabbit aorta using NB100-56583. Secondary antibody: anti-mouse histofine ( Nisherei Bioscience Inc. ref: 414131F). Development: DAB (Dako ref: K346811-2) and counterstained with Hematoxylin. Submitted via verified customer review

Mouse Monoclonal
Species Human, Rat, Rabbit
Applications WB, Flow, IHC

     1 Review

5 Publications
ERK2 Antibody (OTI6E5)
NBP1-47842
Western Blot: ERK2 Antibody (6E5) [NBP1-47842] - Analysis of extracts (35ug) from 9 different cell lines by using anti-ERK2 monoclonal antibody.Immunohistochemistry-Paraffin: ERK2 Antibody (6E5) [NBP1-47842] - Endometrium tissue within the normal limits using antiMAPK1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min,Dilution 1:50)

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

LIS1 Antibody
NBP1-87769
Immunohistochemistry-Paraffin: LIS1 Antibody [NBP1-87769] - Analysis in human testis and liver tissues using NBP1-87769 antibody. Corresponding PAFAH1B1 RNA-seq data are presented for the same tissues.Western Blot: LIS1 Antibody [NBP1-87769] - Analysis of LIS1 in caco-2 whole cell lysate using anti-LIS1 antibody. Image submitted by a verified customer review.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     2 Reviews

APOBEC2 Antibody
NBP1-88848
Immunohistochemistry-Paraffin: APOBEC2 Antibody [NBP1-88848] - Analysis in human skeletal muscle and liver tissues using NBP1-88848 antibody. Corresponding APOBEC2 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: APOBEC2 Antibody [NBP1-88848] - Staining of human heart muscle shows moderate cytoplasmic positivity in cardiomyocytes.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NUDC Antibody
NBP1-89517
Western Blot: NUDC Antibody [NBP1-89517] - Analysis using Anti-NUDC antibody NBP1-89517 (A) shows similar pattern to independent antibody NBP1-89510 (B).Immunocytochemistry/Immunofluorescence: NUDC Antibody [NBP1-89517] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Publication
ARFRP1 Antibody
NBP2-14306
Western Blot: ARFRP1 Antibody [NBP2-14306] - Analysis in control (vector only transfected HEK293T lysate) and ARFRP1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: ARFRP1 Antibody [NBP2-14306] - Staining of human stomach, lower shows strong cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

ACTR1A Antibody
NBP2-15274
Western Blot: ACTR1A Antibody [NBP2-15274] - Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE, antibody diluted at 1:2000.Immunohistochemistry-Paraffin: ACTR1A Antibody [NBP2-15274] - Paraffin-embedded Lung ca, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

ERK1 Antibody (1E5)
NBP2-22203
Western Blot: ERK1 Antibody (1E5) [NBP2-22203] - Western blot analysis of whole cell lysates from (1) MCF7 (2) NIH3T3 cell lines using ERK1 antibody (clone 1E5) at 1:1000 dilution. The signal was developed using HRP labeled goat-anti Mouse secondary antibody with ECL based detection. Immunocytochemistry/Immunofluorescence: ERK1 Antibody (1E5) [NBP2-22203] - Analysis of NIH/3T3 cells using ERK1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, Flow

p21/CIP1/CDKN1A Antibody (WA-1)
NBP2-29463
Immunohistochemistry-Paraffin: p21/CIP1/CDKN1A Antibody (WA-1) [NBP2-29463] - Formalin-fixed, paraffin-embedded human bladder carcinoma stained with p21 Monoclonal Antibody (WA-1).

Mouse Monoclonal
Species Human, Mouse, Chimpanzee
Applications WB, Flow, ICC/IF

17 Publications
Thrombopoietin R/Tpo R Antibody [Unconjugated]
AF1016
<P align=left>Recombinant Human Thrombopoietin/Tpo (Catalog # <A class=NoLineLink href=Simple Western lane view shows lysates of Daudi human Burkitt's lymphoma cell line, loaded at 0.2 mg/mL. A specific band was detected for Thrombopoietin R/Tpo R at approximately 73 kDa (as indicated) using 20 µg/mL of Goat Anti-Human Thrombopoietin R/Tpo R Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1016) . This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Goat Polyclonal
Species Human
Applications WB, Neut

3 Publications
PITX2 Antibody [Unconjugated]
AF7388
PITX2 was detected in immersion fixed paraffin-embedded sections of human thyroid cancer tissue using Sheep Anti-Human PITX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7388) at 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # <A class=NoLineLink href=

Sheep Polyclonal
Species Human
Applications IHC

4 Publications
Angiopoietin-like Protein 1/ANGPTL1 Antibody [Unconjugated]
AF2204
Angiopoietin‑like Protein 1/ANGPTL1 was detected in immersion fixed paraffin-embedded sections of Human Placenta using Goat Anti-Human Angiopoietin‑like Protein 1/ANGPTL1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2204) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # <a class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, IHC

1 Publication
COUP-TF II/NR2F2 Antibody (H7147) [Unconjugated]
PP-H7147-00

Mouse Monoclonal
Species Human
Applications WB, IHC, IP

     3 Reviews

27 Publications
PLA2G7/PAF-AH/Lp-PLA2 [HRP]
DPLG70
PLA2G7/PAF-AH/Lp-PLA2 [HRP] PLA2G7/PAF-AH/Lp-PLA2 [HRP]


Species Human
Applications ELISA

     1 Review

14 Publications
Thrombopoietin/THPO [Unconjugated]
288-TPN/CF
Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED<sub>50</sub> for this effect is 5-15 ng/mL.


Species Human
Applications BA

12 Publications
TNF-alpha [Unconjugated]
210-TA
Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.


Species Human
Applications BA

     3 Reviews

743 Publications
Nesprin 2 Antibody
NBP2-42886
Western Blot: Nesprin 2 Antibody [NBP2-42886] - Various tissue extracts (50 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with Nesprin 2 antibody [C3], C-term diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.Immunocytochemistry/Immunofluorescence: Nesprin 2 Antibody [NBP2-42886] - Analysis of Sample: H1299 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Syne2 protein stained by Syne2 antibody [C3], C-term diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

PCNA Antibody (PC10)
NB500-106
Simple Western: PCNA Antibody (PC10) [NB500-106] - Image shows a specific band for PCNA in 0.5 mg/mL of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.Immunocytochemistry/Immunofluorescence: PCNA Antibody (PC10) [NB500-106] - NIH3T3 cells were fixed and permeabilized for 10 minutes using -20C MeOH. The cells were incubated with anti-PCNA Antibody (PC10) NB500-106 at 1 ug/ml overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:1000 dilution for 60 minutes. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 100X objective and digitally deconvolved.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ChIP

     5 Reviews

40 Publications
Neutrophil Elastase/ELA2 [Biotin]
DY9167-05
Neutrophil Elastase/ELA2 [Biotin]


Species Human
Applications ELISA

14 Publications