Neuroprotection is a mechanism of retaining brain function after a CNS disorder or injury by limiting the number of neurons that are affected in the event. Current research is focusing on using neuroprotection and neuroprotective agents against many debilitating diseases including schizophrenia, stroke, and Parkinson’s disease. Hypoxia and ischemia are also frequently studied for mechanisms of neuroprotection, and scientists have found that erythropoietin is an extremely effective glycoprotein in protecting the neurons from the glutamate toxicity that occurs as a result. Erythropoietin has also been shown to help protect peripheral nerve injuries, leading to the proliferation of Schwann cells through the JAK2 and ERK/MAPK pathways. Other neuroprotective factors include apoptosis inhibitors, free radical trappers and scavengers, endocannabinoids, and certain cellular signaling proteins such as PEBP. Physical methods are also used for neuroprotection, including pressure reduction for glaucoma and therapeutic hypothermia for patients with ischemia.
Neuroprotection Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Neuroprotection below!
For more information on how to use Laverne, please read the How to Guide.
We have 2988 products for the study of the Neuroprotection Pathway that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.
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