Nerve Growth Factor Production Pathway Bioinformatics
The function of nerve growth factors (NGFs) is to aid in axonal growth by binding with two kinds of receptors located on the neuron: p75 LNGFR neurotrophin receptor and TrkA. Both of these receptors have been shown to be affected under conditions that are associated with neurodegenerative diseases. Studies have been conducted on the production of NGFs, and certain cells have been shown to play roles in this process, including lymphocytes, astrocytes, phorbol 12-myristate 13-acetate (PMA) and protein kinase C. In certain cases, NGFs have been shown to induce apoptosis of neurons. There are multiple pathways that can be activated by the binding of NGFs to its receptors, including PI 3-kinase, Ras, and PLC signaling pathways, which not only lead to cell growth and proliferation but to the activation of kinases such as Akt and MAPK.
Nerve Growth Factor Production Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Nerve Growth Factor Production below!
For more information on how to use Laverne, please read the How to Guide.
We have 2105 products for the study of the Nerve Growth Factor Production Pathway that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.