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Lymphangiogenesis Pathway Bioinformatics

Lymphangiogenesis is a phenomenon similar to angiogenesis, in which new lymphatic vessels are formed from pre-existing ones in a method termed sprouting that is initiated by the signaling molecule VEGF-C. Lymphangiogenesis is necessary in establishing homeostasis as well as metabolism and immunity, as many organs of the body require the vessels to transfer their dangerous and unnecessary cells to the lymph nodes in order to properly function. Lymphangiogenesis can, however, help in the progression of diseases such as rheumatoid arthritis, impaired wound healing, and cancer metastasis. If tumor cells are able to reach the lymphatic vessels, they can use them to further travel around the body to the lymph nodes, which can result in a lack of the disease fighting functions that the lymph nodes typically have.

Lymphangiogenesis Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Lymphangiogenesis below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 3207 products for the study of the Lymphangiogenesis Pathway that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NBP1-33050
Western Blot: MVD Antibody [NBP1-33050] - A. 30 ug 293T whole lysate/extract, B. 30 ug A431 whole cell lysate/extract, C. 30 ug HeLa whole cell lysate/extract. D. 30 ug A37C whole cell lysate/extract 10 % SDS-PAGE gel, antibody dilution 1:1000.Immunocytochemistry/Immunofluorescence: MVD Antibody [NBP1-33050] - Paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

NB600-1071
Immunocytochemistry/Immunofluorescence: CD34 Antibody (MEC 14.7) [NB600-1071] - CD34 antibody was tested in WEHI-3 cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and DyLight 550 (red).Immunohistochemistry-Paraffin: CD34 Antibody (MEC 14.7) [NB600-1071] - Analysis of a FFPE tissue section of mouse small intestine using rat anti-mouse CD34 (clone MEC 14.7) at 1:100 dilution. The signal was developed using HRP-conjugated anti-rat secondary with DAB reagent which followed counterstaining of nuclei using hematoxylin. This antibody specifically labelled the endothelial cells in blood vessels located primarily in the sub-mucosa, and of that of the mucosa muscularis and the mucosal lacteal.

Rat Monoclonal
Species Mouse, Human (Negative)
Applications WB, ELISA, Flow

24 Publications
NB110-41083

Goat Polyclonal
Species Human
Applications WB, ChIP, ELISA

11 Publications
AF743
bEnd.3 cells, a mouse endothelioma cell line, was stained with Goat Anti-Mouse VEGFR3/Flt‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF743, filled histogram) or isotype control antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse
Applications WB, Flow, CyTOF-ready

     3 Reviews

68 Publications
AF3244
Western blot shows lysates of mouse lung tissue. PVDF membrane was probed with 0.25 µg/mL of Goat Anti-Mouse Podoplanin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3244) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Podoplanin was detected in perfusion fixed frozen sections of mouse kidney using Goat Anti-Mouse Podoplanin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3244) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Mouse
Applications WB, IHC

     1 Review

44 Publications
AF644
VEGFR2/KDR/Flk‑1 was detected in immersion fixed frozen sections of mouse embryo (14 d.p.c.) using 15 µg/mL Goat Anti-Mouse VEGFR2/KDR/Flk‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF644) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit  (brown; Catalog # <a class=VEGFR2 was detected in acetone fixed cryosections of mouse kidney tissue using Goat Anti-Mouse VEGFR2/KDR/Flk-1 Polyclonal Antibody (Catalog # AF644) for 50 minutes at room temperature. Tissues were stained with rabbit anti-goat secondary<br>antibody and HRP polymer-conjugated anti-rabbit IgG followed by AEC+Substrate Chromogen (red) followed by counterstaining with hematoxylin (blue). Experiments were carried out and the image was provided by Dr. Grietje Molema, University Medical Center Groningen, The Netherlands.

Goat Polyclonal
Species Mouse
Applications WB, Flow, IHC

     3 Reviews

54 Publications
AF2125
LYVE‑1 was detected in perfusion fixed frozen sections of mouse liver using 15 µg/mL Goat Anti-Mouse LYVE‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2125) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit  (brown; Catalog # <a class=  Western  blot shows lysates of mouse liver tissue and bEnd.3 mouse brain  endothelial  cell line. PVDF membrane  was probed with 0.25 µg/mL of Goat Anti-Mouse LYVE‑1  Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2125) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse
Applications WB, IHC

     1 Review

71 Publications
AF3628
  Western  blot shows lysates of bEnd.3 mouse endothelioma cell line. PVDF membrane was  probed with 0.5 µg/mL of Goat Anti-Mouse/Rat CD31/PECAM‑1  Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=Mouse splenocytes were stained with Goat Anti-Mouse/Rat CD31/PECAM‑1 Antigen Affinity‑purified Polyclonal Antibody (Catalog # AF3628, filled histogram) or control antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse, Rat
Applications WB, Flow, IHC

     6 Reviews

201 Publications
AF2727
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human Prox1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2727) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Prox1 was detected in immersion fixed HepG2 human hepatocellular carcinoma cell line using Goat Anti-Human Prox1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2727) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (left panel, red; Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Simple Western, ICC

     4 Reviews

80 Publications
DVED00
 VEGF-D [HRP] VEGF-D [HRP]


Species Human
Applications ELISA

35 Publications
DVE00
 VEGF [HRP] VEGF [HRP]


Species Human
Applications ELISA

629 Publications
802-HC/CF


Species Human
Applications BA, BA

5 Publications
233-FB
Recombinant Human FGF basic/FGF2/bFGF (146 aa) (Catalog # 233-FB) stimulates cell proliferation of the NR6R‑3T3 mouse fibroblast cell line. The activity is approximately 3-fold greater than the top competitor's FGF basic (146 aa).1 µg/lane of Recombinant Human FGF basic/FGF2/bFGF (146 aa) was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.


Species Human
Applications BA

480 Publications
DVEC00
 VEGF-C [HRP] VEGF-C [HRP]


Species Human
Applications ELISA

48 Publications
DVR100C
N/A VEGFR1/Flt-1 [HRP] VEGFR1/Flt-1 [HRP]


Species Human
Applications ELISA

76 Publications