Fibroblast growth factors (FGFs) are involved in a multitude of functions including wound healing, embryonic development, and angiogenesis, and can be the cause of tumor growth and maintenance as they promote endothelial cell growth and capillary differentiation. The FGFs are able to interact with the Ig-like loops on the fibroblast growth factor receptors (FGFRs) can initiate a cascade that leads to mitogenesis and differentiation. There are many pathways that lead to the growth and transformation of the cells via the activation of the FGFRs, and they may include the Ras, MEK, and p38 signaling molecules. There are four different kinds of FGFRs, and FGFR1 has been shown to be related to the Pfeiffer syndrome, while FGFR2 has been linked to various skull mutations.
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Fibroblast Growth Factor Receptor Signaling Pathway below!
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We have 977 products for the study of the Fibroblast Growth Factor Receptor Signaling Pathway that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.