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Dorsal Closure Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Dorsal Closure Pathway and Tissue Adhesions, Nervousness, Stenosis, Salivary Gland Diseases, Neoplasms. The study of the Dorsal Closure Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Dorsal Closure Pathway has been researched in relation to Wound Healing, Localization, Head Involution, Cell Adhesion, Cell Migration. The Dorsal Closure Pathway complements our catalog of research reagents including antibodies and ELISA kits against MAPK, AKT1, CDC42, DCX, DSPP.

Dorsal Closure Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Dorsal Closure below! For more information on how to use Laverne, please read the How to Guide.

Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 813 products for the study of the Dorsal Closure Pathway that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

JNK1 Antibody (228601) [Unconjugated]

MAB17761

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JNK1 was detected in immersion fixed MCF‑7 human breast cancer cell line using Mouse Anti-Human/Mouse/Rat JNK1 Monoclonal Antibody (Catalog # MAB17761) at 10&nbsp;µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights&#8482; 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog&nbsp;# <a class=

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC

2 Reviews

3 Publications

c-jun [p Ser63] Antibody (SY0297)

NBP2-67471

Western Blot: c-jun [p Ser63] Antibody (SY0297) [NBP2-67471] - Analysis of Phospho-c-Jun(S63) on different lysates using anti-Phospho-c-Jun(S63) antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3 Lane 2: 293T

Immunocytochemistry/Immunofluorescence: c-jun [p Ser63] Antibody (SY0297) [NBP2-67471] - Staining Phospho-c-Jun(S63) in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

DSPP Antibody

NBP1-91612

Western Blot: DSPP Antibody [NBP1-91612] - SP2/0 cell lysate, concentration 0.125ug/ml.

Rabbit Polyclonal
Species Mouse
Applications WB

MKK4/MEK4 Antibody (OTI8A8)

NBP1-47839

Western Blot: MKK4/MEK4 Antibody (8A8) [NBP1-47839] - Analysis of extracts (35ug) from 9 different cell lines by using anti-MEK4 monoclonal antibody.

Immunocytochemistry/Immunofluorescence: MKK4/MEK4 Antibody (8A8) [NBP1-47839] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY MEK4.

Mouse Monoclonal
Species Human, Canine
Applications WB, Flow, ICC/IF

CDC42 Antibody

NBP2-14907

Western Blot: CDC42 Antibody [NBP2-14907] - Various whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with CDC42 antibody diluted at 1:500.

Immunohistochemistry-Paraffin: CDC42 Antibody [NBP2-14907] - Paraffin-embedded mouse brain. CDC42 antibody diluted at 1:500.

Rabbit Polyclonal
Species Mouse, Rat
Applications WB, IHC, IHC-P

1 Review

c-Fos Antibody

NB110-75039

Western Blot: c-Fos Antibody [NB110-75039] - Analysis on marmoset brain lysate prepared in Ripa buffer containing 1% Triton-X100; 1% SDS and 1% SDC. Blocking: 1% LFDM for 30 min at RT; primary antibody dilution 1:2000incubated at 4C overnight.

Immunocytochemistry/Immunofluorescence: c-Fos Antibody [NB110-75039] - Rat trigeminal using Rabbit antibody to cFos: whole serum at a 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Review

1 Publication

Doublecortin Antibody (3E1)

NBP1-92684

Western Blot: Doublecortin Antibody (3E1) [NBP1-92684] - Analysis of rat whole brain lysates using mouse mAb to Doublecortin (DCX), NBP1-92684, dilution 1:1,000 in green: [1] protein standard (red), [2] adult rat brain, [3] embryonic E20 rat brain. Strong bands at 40, 45kDa correspond to DCX protein, detected only in the developing brain.

Immunocytochemistry/Immunofluorescence: Doublecortin Antibody (3E1) [NBP1-92684] - Analysis of cortical neuron-glial cell culture from E20 rat stained with mouse mAb to Doublecortin (DCX), NBP1-92684, dilution 1:1,000 in red, and costained with chicken pAb to Microtubule Associated Protein2 (MAP2), dilution 1:10,000 in green. The blue is DAPI staining of nuclear DNA. DCX antibody reveals strong cytoplasmic staining in a population of small developing neurons and their processes, while MAP2 antibody stains dendrites and perikarya of mature neurons. Therefore DCX antibody is an excellent marker of developing neuronal cells.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

Rhodopsin Antibody (A531)

NBP2-25159

Western Blot: Rhodopsin Antibody (A531) [NBP2-25159] - Blot of bovine retinal extracts. The antibody stains a band corresponing to retinal Rhodopsin at about 35kDa. Bands about 70 kDa and 140 kDa are aggregated forms of Rhodopsin. Note, due to the highly hydrophobic nature of Rhodopsin, it is important not to boil a sample containing it in SDS-PAGE sample buffer, as this will result in more extensive aggregation of the Rhodopsin protein.

Immunocytochemistry/Immunofluorescence: Rhodopsin Antibody (A531) [NBP2-25159] - Pig retinal section stained with NBP2-25159 (green) and counterstained with rabbit polyclonal antibody to NF-M NB300-133 (red) and DNA (blue). Rhodopsin is most abundant in the outer segments of retina (OS), NF-M is abundant in the optic nerve fiber layer (ONFL), but seen in processes and neurons in other regions also. Other layers are pigmented epithelium (PE), outer and inner nuclear layers (ONL, INL), outer and inner plexiform layers (OPL, IPL) and ganglion cell layer (GCL).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Publication

RhoD Antibody

NBP1-58359

Western Blot: RhoD Antibody [NBP1-58359] - Transfected 293T, Antibody Titration: 0.2-1 ug/ml

Immunohistochemistry: RhoD Antibody [NBP1-58359] - Human Liver Tissue Observed Staining: Cytoplasm in sinusoids of liver Primary Antibody Concentration: 1 : 100 Other Working Concentrations: 1/600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1 : 200 Magnification: 20X Expos

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

EphB6 Antibody

AF611

Western blot shows lysates of mouse thymus tissue and mouse brain tissue. PVDF membrane was probed with 1&nbsp;µg/mL of Goat Anti-Mouse EphB6 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF611) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog&nbsp;# <A class=NoLineLink href=

Goat Polyclonal
Species Mouse
Applications WB

4 Publications

Heparanase/HPSE [Unconjugated]

7570-GH

Species Human

5 Publications

Myosin Heavy Chain Antibody (MF20) [Unconjugated]

MAB4470

Myosin Heavy Chain was detected in immersion fixed C2C12 mouse myoblast cell line using Mouse Anti-Human Myosin Heavy Chain Monoclonal Antibody (Catalog # MAB4470) at 10&nbsp;µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights&#8482; 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog&nbsp;# <A class=NoLineLink href=

Mouse Monoclonal
Species Multi-Species
Applications WB, ICC

2 Reviews

25 Publications

AKT [p Ser473] Antibody - Pan Specific

AF887

Western blot shows lysates of NIH‑3T3 mouse embryonic fibroblast cell line untreated (-) or treated (+) with 100&nbsp;ng/mL Human&nbsp;PDGF&nbsp;(Catalog&nbsp;#<A class=NoLineLink href=

Akt phosphorylated at S473 was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using Rabbit Anti-Human/Mouse/Rat Phospho-Akt (S473) Antigen Affinity-purified Polyclonal Antibody (Catalog&nbsp;# AF887) at 10&nbsp;µg/mL overnight at 4&nbsp;°C. Tissue was stained using the Anti-Rabbit HRP-DAB Cell &amp; Tissue Staining Kit (brown; Catalog&nbsp;# <A class=NoLineLink href=

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

19 Publications

Rac1 Antibody

NB100-91266

Immunocytochemistry/Immunofluorescence: Rac1 Antibody [NB100-91266] - Mouse Brain (cerebral cortex), Image is courtesy of customer review.

Immunohistochemistry: Rac1 Antibody [NB100-91266] - Rat ligated sciatic nerve using Rabbit antibody to RAC1, RAC2 whole serum at 1:1000 dilution. Pre-absorption of the antibody with the immunizing peptide completely abolishes the immunostaining (not shown).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications ICC/IF, IHC, IHC-Fr

1 Review

3 Publications

Moesin Antibody (MSN/491)

NBP2-32875

Western Blot: Moesin Antibody (MSN/491) [NBP2-32875] - Analysis using the Azide and BSA Free version of NBP2-32875. Detection of Moesin in human HT29 Cells.

Immunohistochemistry-Paraffin: Moesin Antibody (MSN/491) [NBP2-32875] - Fomalin-paraffin Rat colon stained with Moesin MAb (MSN/491)

Mouse Monoclonal
Species Human, Rat
Applications WB, Simple Western, Flow

SGSM3 Antibody

NBP2-13304

Western Blot: SGSM3 Antibody [NBP2-13304] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4

Immunocytochemistry/Immunofluorescence: SGSM3 Antibody [NBP2-13304] - Immunofluorescent staining of human cell line MCF7 shows localization to the Golgi apparatus.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

FosB/G0S3 Antibody (83B1138)

NB100-56530

Western Blot: FosB/G0S3 Antibody (83B1138) [NB100-56530] - Analysis of FosB in HeLa cell lysate where bands are observed ~38 kDa representing FosB and ~35 kDa representing delta FosB.

Mouse Monoclonal
Species Human
Applications WB

JunD [p Ser255] Antibody (JJ08-21)

NBP2-67861

Immunocytochemistry/Immunofluorescence: JunD [p Ser255] Antibody (JJ08-21) [NBP2-67861] - Staining Phospho-JunD(S255) in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Immunohistochemistry-Paraffin: JunD [p Ser255] Antibody (JJ08-21) [NBP2-67861] - Analysis of paraffin-embedded mouse liver tissue using anti-Phospho-JunD(S255) antibody. Counter stained with hematoxylin.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

JunB/AP-1 Antibody

NBP1-89544

Western Blot: JunB/AP-1 Antibody [NBP1-89544] - Analysis in human cell lines MCF-7 and HEK293 using anti-JUNB antibody. Corresponding JUNB RNA-seq data are presented for the same cell lines. Loading control: anti-PFN1.

Immunocytochemistry/Immunofluorescence: JunB/AP-1 Antibody [NBP1-89544] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Related Genes

The Dorsal Closure Pathway has been researched against:

Related Pathways

The Dorsal Closure Pathway has been linked to:

Related Diseases

The Dorsal Closure Pathway has been studied in relation to diseases such as:

Related PTMs

The Dorsal Closure Pathway has been studied in relation to posttranslational modifications (PTMs) including:

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