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Cornification Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Cornification Pathway and Ichthyoses, Dermatologic Disorders, Neoplasms, Carcinoma, Hyperkeratosis. The study of the Cornification Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Cornification Pathway has been researched in relation to Keratinization, Estrus, Secretion, Ovulation, Diestrus. The Cornification Pathway complements our catalog of research reagents including antibodies and ELISA kits against PROFILAGGRIN, CST6, DBT, EGF, ESR1.

Cornification Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Cornification below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1140 products for the study of the Cornification Pathway that can be applied to Western Blot, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-87528
Immunocytochemistry/Immunofluorescence: Filaggrin Antibody [NBP1-87528] - Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.Immunohistochemistry-Paraffin: Filaggrin Antibody [NBP1-87528] - Analysis in human skin and kidney tissues using Anti-FLG antibody. Corresponding FLG RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP2-38770
Western Blot: PLOD1 Antibody [NBP2-38770] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MGImmunohistochemistry-Paraffin: PLOD1 Antibody [NBP2-38770] - Staining of human placenta shows cytoplasmic positivity in decidual cells.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

1 Publication
NB100-1844
Western Blot: Transglutaminase 1/TGM1 Antibody [NB100-1844] - Antibody at 1/200 dilution of an extract from human epidermis.Immunocytochemistry/Immunofluorescence: Transglutaminase 1/TGM1 Antibody [NB100-1844] - Epidermal keratinocytes from neonatal foreskin stained in immunofluorscene with Transglutaminase

Rabbit Polyclonal
Species Human
Applications WB, ELISA, ICC/IF

2 Publications
NB100-74413
Western Blot: ER alpha/NR3A1 Antibody (EVG F9) [NB100-74413] - Analysis of various whole cell lysates.Immunocytochemistry/Immunofluorescence: ER alpha/NR3A1 Antibody (EVG F9) [NB100-74413] - Analysis of Estrogen Receptor alpha using Anti-Estrogen Receptor alpha Monoclonal Antibody (EVG F9) shows staining in U251 Cells. Estrogen Receptor alpha staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing Estrogen Receptor alpha at a dilution of 1:200 over night at 4C, washed with PBS and incubated with a DyLight-488 conjugated.

Mouse Monoclonal
Species Human, Mouse, Rabbit
Applications WB, ICC/IF, IHC

NB100-2756
Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody (LHK1) [NB100-2756] - IHC analysis of a formalin fixed paraffin-embedded (FFPE) human breast cancer using 5ug/ml conc. of Cytokeratin 1 antibody (clone LHK1) on a Bond Rx autostainer (Leica Biosystems). The assay involved 20 minutes of heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0) and endogenous peroxidase quenching with peroxide block. The sections were incubated with primary antibody for 30 minutes and Bond Polymer Refine Detection (Leica Biosystems) with DAB was used for signal development followed by counterstaining with hematoxylin. Whole slide scanning and capturing of representative images (20X) was performed using Aperio AT2 (Leica Biosystems). A membrane-cytoplasmic staining of Cytokeratin 1 was observed in the cancer cells with signal localized more to the cell membranes. Tumor cores showed a decreased staining and tumor stroma was mostly negative for Cytokeratin 1.Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody (LHK1) [NB100-2756] - IHC analysis of a formalin fixed paraffin-embedded (FFPE) human breast cancer using 5ug/ml conc. of Cytokeratin 1 antibody (clone LHK1) on a Bond Rx autostainer (Leica Biosystems). The assay involved 20 minutes of heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0) and endogenous peroxidase quenching with peroxide block. The sections were incubated with primary antibody for 30 minutes and Bond Polymer Refine Detection (Leica Biosystems) with DAB was used for signal development followed by counterstaining with hematoxylin. Whole slide scanning and capturing of representative images (20X) was performed using Aperio AT2 (Leica Biosystems). A membrane-cytoplasmic staining of Cytokeratin 1 was observed in the cancer cells with signal localized more to the cell membranes. Tumor stroma was mostly negative for Cytokeratin 1. Staining was performed by Histowiz.

Mouse Monoclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

9 Publications
NBP1-33610
Western Blot: Loricrin Antibody [NBP1-33610] - Whole cell extract (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with Loricrin antibody [N1], N-term diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: Loricrin Antibody [NBP1-33610] - Immunofluorescence:  [NBP1-33610] - Analysis of methanol-fixed Hep3B, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     1 Review

1 Publication
NBP1-89522
Western Blot: DBT Antibody [NBP1-89522] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).Immunocytochemistry/Immunofluorescence: DBT Antibody [NBP1-89522] - Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NB100-2727
Immunohistochemistry-Paraffin: Involucrin Antibody (SY5) [NB100-2727] - Staining of human Tonsil with Involucrin Monoclonal Antibody (SY5).

Mouse Monoclonal
Species Human, Porcine, Canine
Applications WB, Flow, ICC/IF

1 Publication
NBP2-32962
Flow Cytometry: Cytokeratin 10 Antibody (SPM261) [NBP2-32962] - Analysis using Alexa Fluor (R) 647 conjugate of NBP2-32962. An intracellular stain was performed on HeLa cells with Cytokeratin 10 antibody (SPM261) NBP2-34752 (blue) and a matched isotype control NBP2-27287 (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. 1 microgram of antibody was added to 100 uL of staining buffer and cells were incubated for 30 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 647.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

AF682
Prolactin was detected in immersion fixed paraffin-embedded sections of human testis using Goat Anti-Human Prolactin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF682) at 1 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=    Western  blot shows lysates of human pituitary tissue. PVDF membrane was probed with  0.25 µg/mL of Goat Anti-Human Prolactin Antigen Affinity-purified  Polyclonal Antibody (Catalog # AF682) followed by HRP-conjugated Anti-Goat  IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, IHC, ELISA(Cap)

3 Publications
AF1286
    Western  blot shows lysates of human skin tissue. PVDF membrane was probed with  1 µg/mL of Goat Anti-Human Cystatin E/M Antigen  Affinity-purified Polyclonal Antibody (Catalog # AF1286) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=    Simple  Western lane view shows lysates of human skin tissue, loaded at  0.2 mg/mL. A specific band was detected for Cystatin E/M at  approximately 13 kDa (as indicated) using 50 µg/mL of Goat  Anti-Human Cystatin E/M Antigen Affinity-purified Polyclonal  Antibody (Catalog # AF1286) followed by 1:50 dilution of HRP-conjugated  Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Simple Western, IHC

     1 Review

3 Publications
NBP1-30475
Western Blot: BRD2 Antibody [NBP1-30475] - Detection of Human and Mouse BRD2 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-BRD2 antibody NBP1-30475 used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.Immunocytochemistry/Immunofluorescence: BRD2 Antibody [NBP1-30475] - Affinity purified rabbit anti-BRD2 used at a dilution of 1:100 (2ug/ml). Detection: Red-fluorescent goat anti-rabbit IgG cross-adsorbed Antibody DyLight 594 conjugated.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
236-EG
Recombinant Human EGF (Catalog # 236‑EG) stimulates cell proliferation of the Balb/3T3 mouse embryonic fibroblast cell line. The ED<sub>50</sub> for this effect is 20‑100 pg/mL.1 µg/lane of Recombinant Human EGF was resolved with SDS-PAGE  and visualized by silver staining under reducing (R) conditions, showing a single band at 6 kDa.


Species Human

     8 Reviews

256 Publications
NB100-56126
Western Blot: Caspase-14 Antibody [NB100-56126] -  Analysis of Caspase-14. Tissue lysates (50 ug/lane) and recombinant human Caspase-14 were (Hu C14, 15 ng) were western blotted with Caspase-14 antibody at 1:2000. The antibody detected both the proform of caspase-14, and the large and small subunits of active/cleaved caspase-14.Immunohistochemistry: Caspase-14 Antibody [NB100-56126] - Immunohistochemistry-Paraffin: Caspase-14 Antibody [NB100-56126] - Tissue sections of mouse skin at E17 stained using this antibody at 1:500.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

5 Publications
AF5415
Western blot shows lysates of T47D human breast cancer cell line. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human Progesterone R/NR3C3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5415) followed by HRP‑conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=    Progesterone R/NR3C3  was detected in immersion fixed T47D human breast cancer cell line using  Sheep Anti-Human Progesterone R/NR3C3 Antigen Affinity-purified  Polyclonal Antibody (Catalog # AF5415) at 1.7 µg/mL for 3  hours at room temperature. Cells were stained using the  NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody  (red; Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB, IHC, ICC

1 Publication
NBP2-50037
Western Blot: c-Fos Antibody (2H2) [NBP2-50037] - Top panel: Analysis of c-Fos expression in HeLa cells using NBP2-50037. Lane 1: HeLa cells were serum-starved for 36 hours.  Lane 2: Serum-starved HeLa cells were stimulated with 20% FBS (fetal bovine serum) for 2 hours. NBP2-50037 recognizes bands in the range of 50-65 kDa, which represent multiple forms of c-Fos. Serum starvation attenuates c-Fos expression, while 20% FBS strongly stimulates c-Fos expression.  Bottom panel: Blot was stripped and probed with monoclonal antibody against GAPDH (NB300-221) used as loading control.Immunocytochemistry: c-Fos Antibody (2H2) [NBP2-50037] - pAb 1:1000 (green), DAPI counterstain (blue) on 30 micron cryosection of mouse spinal cord. This image was submitted via customer Review.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, ICC

     1 Review

NBP1-80687
Immunohistochemistry-Paraffin: Trichohyalin Antibody [NBP1-80687] - Staining of human placenta shows strong cytoplasmic and nuclear positivity in trophoblastic cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

AF4928
K562 human chronic myelogenous leukemia cell line was stained with Goat Anti-Human ERMAP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4928, filled histogram) or control antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, Flow, CyTOF-ready