Connective Tissue Growth Factor Production Pathway Bioinformatics
Connective tissue growth factors (CTGFs) bind to various cell surface receptors such as integrin receptors, LRPs, TrkA, and HSPGs as well as other growth factors and other extracellular matrix proteins that facilitate the growth of connective tissues including fibrous and adipose connective tissue. CTGF is secreted and functions as a downstream target for TGF-beta activation, which causes cell adhesion as well as chondrocyte proliferation and differentiation. Because of this, CTGF plays a role in wound healing as well as other fibrotic pathways including atherosclerosis. The production of CTGF can be initiated by a variety of molecules, including ethanol-activated pancreatic stellate cells, arecoline, bioactive lipids, and angiotensin II. The production of this growth factor occurs via the signaling of GTPases including RhoA, Rac, and Cdc42.
Connective Tissue Growth Factor Production Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Connective Tissue Growth Factor Production below!
For more information on how to use Laverne, please read the How to Guide.
We have 1289 products for the study of the Connective Tissue Growth Factor Production Pathway that can be applied to Flow Cytometry, Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.