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Complement-dependent Cytotoxicity Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Complement-dependent Cytotoxicity Pathway and Neoplasms, Malignant Neoplasms, Lymphoma, Leukemia, Carcinoma. The study of the Complement-dependent Cytotoxicity Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Complement-dependent Cytotoxicity Pathway has been researched in relation to Antibody-dependent Cellular Cytotoxicity, Immune Response, Complement Activation, Sensitization, Cell Death. The Complement-dependent Cytotoxicity Pathway complements our catalog of research reagents including antibodies and ELISA kits against MS4A1, KRT20, HLA-DRB4, CD55, IL2.

Complement-dependent Cytotoxicity Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Complement-dependent Cytotoxicity below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 3807 products for the study of the Complement-dependent Cytotoxicity Pathway that can be applied to Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence from our catalog of antibodies and ELISA kits.

CD20 Antibody (AISB12)
NBP1-43435
Western Blot: MS4A1/CD20 Antibody (AISB12) [NBP1-43435] - Immunoblot of Balb/c thymus (lane 1) and A20 (lane 2) cell lysates with Anti-Mouse CD20 Purified.Flow Cytometry: MS4A1/CD20 Antibody (AISB12) [NBP1-43435] - Staining of BALB/c splenocytes with Anti-Mouse CD19 Alexa Fluor (R) 647 and 1.0 micrograms conjugated anti-Mouse CD20 Purified followed by Anti-Rat IgG PE. Quadrant lines represent Rat IgG2a isotype control staining levels and cells in the lymphocyte gate were used for analysis.

Rat Monoclonal
Species Human, Mouse
Applications WB, Flow

3 Publications
Cytokeratin 20 Antibody
NBP1-85599
Western Blot: Cytokeratin 20 Antibody [NBP1-85599] - Analysis in human small intestine tissue.Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody [NBP1-85599] - Analysis in human small intestine and liver tissues. Corresponding KRT20 RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

1 Publication
HLA DRB4 Antibody (4C8)
H00003126-M01
Western Blot: HLA DRB4 Antibody (4C8) [H00003126-M01] - HLA-DRB4 monoclonal antibody (M01), clone 4C8. Analysis of HLA-DRB4 expression in human kidney.Immunohistochemistry-Paraffin: HLA DRB4 Antibody (4C8) [H00003126-M01] - Analysis of monoclonal antibody to HLA-DRB4 on formalin-fixed paraffin-embedded human tonsil. Antibody concentration 1 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

1 Publication
CD55/DAF Antibody (MEM-118)
NB500-395
Flow (Cell Surface): CD55/DAF Antibody (MEM-118) [NB500-395] - Surface staining of human peripheral blood cells with anti-CD55 (MEM-118) purified, GAM-APC.Flow (Cell Surface): CD55/DAF Antibody (MEM-118) [NB500-395] - Surface staining of human peripheral blood leukocytes by mouse monoclonal anti-CD55 antibody MEM-118.

Mouse Monoclonal
Species Human, Primate
Applications Flow, IHC, IHC-P

IL-2 [Unconjugated]
202-IL
1 μg/lane of Recombinant Human IL-2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.Recombinant Human IL-2 (Catalog # 202-IL) stimulates cell proliferation of the CTLL‑2 mouse cytotoxic T cell line. The ED<SUB>50</SUB> for this effect is 0.05-0.25 ng/mL.


Species Human

     18 Reviews

278 Publications
CD59 Antibody (MEM-43)
NB500-330
Immunohistochemistry-Frozen: CD59 Antibody (MEM-43) [NB500-330] - Human tonsil frozen tissue section stained for CD59 (red) and counterstained with DAPI (blue). Image from verified customer review.Flow Cytometry: CD59 Antibody (MEM-43) [NB500-330] - Surface staining of HL-60 (positive) and SP2 (negative) cells with anti-human CD59 (MEM-43) Pacific BlueTM.

Mouse Monoclonal
Species Human
Applications Flow, IHC, IHC-Fr

     1 Review

5 Publications
HLA ABC Antibody (W6/32)
NB100-64775
Flow Cytometry: HLA ABC Antibody (W6/32) [NB100-64775] - Analysis using the FITC conjugate of NB100-64775. Staining of normal human peripheral blood cells with Mouse IgG2a K Isotype Control FITC (NBP1-43955) (blue histogram) or Anti-Human HLA-ABC FITC (purple histogram). Cells in the lymphocyte gate were used fFlow Cytometry: HLA ABC Antibody (W6/32) [NB100-64775] - Staining of human peripheral blood lymphocytes with Mouse anti Human HLA ABC.

Mouse Monoclonal
Species Human, Baboon, Bovine
Applications ELISA, Flow, ICC/IF

     1 Review

23 Publications
ErbB2/Her2 [Unconjugated]
1129-ER
1 μg/lane of Recombinant Human ErbB2 Fc Chimera was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 125-130 kDa and  220-250 kDa, respectively.


Species Human

     9 Reviews

35 Publications
TNF-alpha [Unconjugated]
210-TA
Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.


Species Human

     24 Reviews

602 Publications
Human IgG3 Isotype Control
DDXCH03P-100

Human Polyclonal
Species Human
Applications Flow, IHC-Fr, IHC-P

Complement C3 Antibody (11H9)
NB200-540
Flow (Intracellular): Complement C3 Antibody (11H9) [NB200-540] - An intracellular stain was performed on RAW 246.7 cells with Complement C3 (11H9-3-2) antibody NB200-540 (blue) and a matched isotype control NBP2-31382 (orange). Cells were either treated with 3uM Monensin for 3 hours to block the secretion of Complement C3 (B) or grown in normal media (A). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2 ug/mL for 30 minutes at room temperature, followed by mouse F(ab)2 IgG (H+L) PE-conjugated secondary antibody (F0102B, R&D Systems).Immunocytochemistry/Immunofluorescence: Complement C3 Antibody (11H9) [NB200-540] - C3 protein fragments deposited on kidney cells of MPL-lpr mouse. Staining with antibody 11H9. Glomerular staining pattern. Fixation in 4% paraformaldehyde in PBS pH 7.4. Vibratome sections of 4 um. Pretreated with 3% hydrogen peroxide for 20 min to quench endogenous peroxidases. Microwaved in antigen unmasking solution for 2-5 minutes as antigen retrieval.

Rat Monoclonal
Species Mouse
Applications Flow, IA, ICC/IF

     2 Reviews

3 Publications
HLA DQ Antibody (SPV-L3)
NBP2-45041

Mouse Monoclonal
Species Human, Porcine
Applications Flow, IHC, IHC-Fr

CTLA-4 [Unconjugated]
7268-CT
Recombinant Human CTLA-4 Fc Chimera (Catalog # 7268-CT) inhibits IL-2 secretion by stimulated Jurkat human acute Tcell leukemia cells. The ED<sub>50</sub> for this effect is 0.03-0.15 μg/mL whenstimulated with 1 μg/mL Recombinant Human B7‑1/CD80 Fc Chimera (Catalog # <a class=


Species Human

     3 Reviews

1 Publication
CD46 Antibody (344519)
MAB2005

Mouse Monoclonal
Species Human
Applications WB, Flow, CyTOF-ready

     1 Review

3 Publications
NOD2 Antibody (2D9)
NB100-524
Western Blot: NOD2 Antibody (2D9) [NB100-524] - Total protein from human THP1 and US-OS cells and mouse Raw264.7 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-NOD2 in 1% non-fat milk in TBST and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: NOD2 Antibody (2D9) [NB100-524] - A431 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton X-100. The cells were incubated with anti-NOD2 (2D9) NB100-524 at a 1:200 dilution overnight at 4C and detected with an anti-mouse DyLight 488 (Green) at a 1:500 dilution. Actin was counterstained with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

     1 Review

16 Publications
EGFR [p Tyr1173] Antibody [Unconjugated]
AF1095
Western blot shows lysates of A431 human epithelial carcinoma cell line untreated<br>(‑) or treated (+) with 100 μM pervanadate (PV) for 10 minutes. PVDF membrane was probed with 0.2 µg/mL of Rabbit Anti-Human Phospho-EGFR (Y1173) Antigen Affinity-purified Polyclonal Antibody, followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # <a class=Simple Western lane view shows lysates of A431 human epithelial carcinoma cell line untreated (-) or treated (+) with 10 ng/mL Recombinant Human EGF (Catalog # <a class=

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, IHC

5 Publications
S100A6 Antibody
NBP1-89388
Western Blot: S100A6 Antibody [NBP1-89388] - Analysis in human cell lines PC-3 and HEK293 using anti-S100A6 antibody. Corresponding S100A6 RNA-seq data are presented for the same cell lines. Loading control: anti-PFN1.Immunocytochemistry/Immunofluorescence: S100A6 Antibody [NBP1-89388] - Staining of human cell line U-251 MG shows localization to plasma membrane & cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

2 Publications
HLA B Antibody (2A11G7)
NBP2-61872
Western Blot: HLA B Antibody (2A11G7) [NBP2-61872] - Analysis using HLA-B mAb against HEK293 (1) and HLA-B (AA: 241-362)-hIgGFc transfected HEK293 (2) cell lysate.Immunohistochemistry-Paraffin: HLA B Antibody (2A11G7) [NBP2-61872] - Analysis of bladder cancer tissues using HLA-B mouse mAb with DAB staining.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

Fc gamma RIIIA/CD16a
4325-FC
1 μg/lane of Recombinant Human Fc gamma  RIIIA/CD16a was resolved with SDS‑PAGE under reducing (R) conditions and visualized by silver staining, showing bands at 40‑50 kDa.Recombinant Human Fc gamma  RIIIA/CD16a (Catalog # 4325-FC) binds human IgG with an estimated K<SUB>d</SUB> <50 nM.


Species Human

     6 Reviews

13 Publications