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Complement Activation Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Complement Activation Pathway and Inflammation, Hemolysis (disorder), Autoimmune Reaction, Lupus Erythematosus, Systemic, Inflammatory Response. The study of the Complement Activation Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Complement Activation Pathway has been researched in relation to Pathogenesis, Coagulation, Inflammatory Response, Immune Response, Phagocytosis. The Complement Activation Pathway complements our catalog of research reagents including antibodies and ELISA kits against C3, C4A, C5AR1, C5, CFH.

Complement Activation Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Complement Activation below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2579 products for the study of the Complement Activation Pathway that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NB200-540
Flow (Intracellular): Complement C3 Antibody (11H9) [NB200-540] - An intracellular stain was performed on RAW 246.7 cells with Complement C3 (11H9-3-2) antibody NB200-540 (blue) and a matched isotype control NBP2-31382 (orange). Cells were either treated with 3uM Monensin for 3 hours to block the secretion of Complement C3 (B) or grown in normal media (A). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2 ug/mL for 30 minutes at room temperature, followed by mouse F(ab)2 IgG (H+L) PE-conjugated secondary antibody (F0102B, R&D Systems).Immunocytochemistry/Immunofluorescence: Complement C3 Antibody (11H9) [NB200-540] - C3 protein fragments deposited on kidney cells of MPL-lpr mouse. Staining with antibody 11H9. Glomerular staining pattern. Fixation in 4% paraformaldehyde in PBS pH 7.4. Vibratome sections of 4 um. Pretreated with 3% hydrogen peroxide for 20 min to quench endogenous peroxidases. Microwaved in antigen unmasking solution for 2-5 minutes as antigen retrieval.

Rat Monoclonal
Species Mouse
Applications Flow, IA, ICC/IF

     2 Reviews

6 Publications
MAB36481
HEK293 human  embryonic kidney cell line transfected with either (A) human C5aR or (B) irrelevant protein and eGFP was stained  with  Mouse Anti-Human C5aR Monoclonal Antibody (Catalog # MAB36481)  followed  by Allophycocyanin-conjugated Anti-Mouse IgG Secondary  Antibody (Catalog # <a class=    Complement  Component C5aR1 was detected in immersion fixed U937 human histiocytic  lymphoma cell line (positive) and SH‑SY5Y human neuroblastoma cell  line (negative control) using Mouse Anti-Human Complement Component C5aR1  Monoclonal Antibody (Catalog # MAB36481) at 8 µg/mL for 3  hours at room temperature. Cells were stained using the  NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody  (red; Catalog # <a class=

Mouse Monoclonal
Species Human
Applications Flow, IHC, CyTOF-ready

2150-C5/CF
<P align=left>1 μg/lane of Recombinant Mouse Complement Component C5a was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 9 kDa.</P>Recombinant Mouse Complement Component C5a (Catalog # 2150-C5/CF) induces N-acetyl-beta -D-glucosaminidase release from differentiated U937 human histiocytic lymphoma cells. The ED<SUB>50</SUB> for this effect is 5-20 ng/mL.


Species Mouse

31 Publications
AF4779
Complement Factor H was detected in immersion fixed paraffin-embedded sections of human liver using Goat Anti-Human Complement Factor H Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4779) at 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # <A class=

Goat Polyclonal
Species Human
Applications WB, IHC

     1 Review

MAB5376
Western blot shows lysates of mouse splenocytes. PVDF Membrane was probed with 2 µg/mL of Rat Anti-Mouse CD55/DAF Monoclonal Antibody (Catalog # MAB5376) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=        Western  blot shows lysates of mouse spleen tissue and mouse splenocytes. PVDF  membrane was probed with 2 µg/mL of Rat Anti-Mouse CD55/DAF  Monoclonal Antibody (Catalog # MAB5376) followed by HRP-conjugated Anti-Rat  IgG Secondary Antibody (Catalog # <a class=

Rat Monoclonal
Species Mouse
Applications WB, Flow, CyTOF-ready

1 Publication
AF2307

Goat Polyclonal
Species Human
Applications WB, ELISA(Cap), ELISA(Det)

6 Publications
MAB2005

Mouse Monoclonal
Species Human
Applications WB, Flow, CyTOF-ready

     1 Review

3 Publications
NB500-330
Immunohistochemistry-Paraffin: CD59 Antibody (MEM-43) [NB500-330] - Staining of human placenta (paraffin sections) using anti-CD59 (MEM-43).Flow Cytometry: CD59 Antibody (MEM-43) [NB500-330] - Surface staining of HL-60 (positive) and SP2 (negative) cells with anti-human CD59 (MEM-43) Pacific BlueTM.

Mouse Monoclonal
Species Human
Applications Flow, IHC, IHC-Fr

     1 Review

5 Publications
210-TA
1 µg/lane of Recombinant Human TNF-alpha  was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.Recombinant Human TNF-alpha  (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.


Species Human

     2 Reviews

637 Publications
NBP2-67656
Western Blot: hnRNP C1 + C2 Antibody (SN0652) [NBP2-67656] - Analysis of hnRNP C1+C2 on different lysates using anti-hnRNP C1+C2 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: MCF-7 Lane 3: HepG2Immunocytochemistry/Immunofluorescence: hnRNP C1 + C2 Antibody (SN0652) [NBP2-67656] - Staining hnRNP C1+C2 in B16-F1 (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

DCRP00
 C-Reactive Protein/CRP [HRP] C-Reactive Protein/CRP [HRP]


Species Human

78 Publications
MAB1936

Mouse Monoclonal
Species Human
Applications WB, IP

1 Publication
NBP1-89985
Western Blot: Complement Factor B Antibody [NBP1-89985] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.Immunocytochemistry/Immunofluorescence: Complement Factor B Antibody [NBP1-89985] - Staining of human cell line ASC TERT1 shows localization to endoplasmic reticulum. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

5 Publications
7270-IL/CF


Species Human

NBP2-29460
Immunohistochemistry-Paraffin: CD35 Antibody (E11) [NBP2-29460] - Hhuman Tonsil stained with CD35 Antibody (E11).Immunohistochemistry-Paraffin: CD35 Antibody (E11) [NBP2-29460] - Formalin-fixed, paraffin-embedded human tonsil stained with CD35 antibody at 1:200 using peroxidase-conjugate and DAB chromogen. Note membrane staining.

Mouse Monoclonal
Species Human, Monkey
Applications WB, ELISA, Flow

5 Publications
NB600-41532
Western Blot: Albumin Antibody [NB600-41532] - Analysis using the HRP conjugate of NB600-41532. Detection of Albumin in whole mouse liver extracts. Image courtesy of anonymous customer product review.

Goat Polyclonal
Species Human, Mouse
Applications WB, ELISA, ICC/IF

36 Publications