Apoptosis is a form of programmed cell death, which can be either a developmental process or a response from the human immune system. During apoptosis, the cell undergoes changes including chromosomal condensation, nuclear and chromosomal DNA fragmentation, and blebbing. There are both intrinsic (such as DNA lesions) and extrinsic pathways, such as the p53 pathway, that cause to apoptosis, and they lead to the activation of caspases that initiate the destruction of various components of the cell, resulting in its ultimate death. There are several factors that contribute to the commitment of apoptosis, including a lower mitochondrial membrane potentials and Bcl-2 proteins such as Bax and Bak, which lead to the permeabilization of the mitochondrial membrane. The protein TNF-alpha has also been shown to induce apoptosis, as well as the inhibition of actin polymerization.
Commitment To Apoptosis Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Commitment To Apoptosis below!
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We have 3341 products for the study of the Commitment To Apoptosis Pathway that can be applied to Flow Cytometry, Western Blot, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.