Cellular Response To Hypoxia Pathway Bioinformatics
Hypoxia occurs when a region of the body is deprived of oxygen. Hypoxia is a very dangerous condition when the brain is affected, for neurons can begin to die off within a matter of minutes, especially in cases of complete oxygen deprivation, or anoxia. Anaerobic metabolism occurs when the cells are not receiving oxygen, which results in a buildup of lactic acid, and could lead to cell death if oxygen is not soon introduced. Chemoreceptors in the carotid body are able to detect changes in the oxygen level of cells, and cause a response of vasodilation, or the widening of blood vessels to increase blood flow and allow for greater perfusion. Other methods of restoring oxygen levels include hyperventilation and adaptation, which is controlled by the hypoxia-inducible factor 1 (HIF-1). In response to hypoxia response elements, HIF-1 is able to control microRNAs, which can help the body adapt to low levels of oxygen through routes such as metabolic, apoptotic, proliferative, and angiogenic adaptations.
Cellular Response To Hypoxia Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Cellular Response To Hypoxia below!
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