Disease and disorder research has been conducted in relation to the Cell Fate Specification Pathway and Nervousness, Neoplasms, Malignant Neoplasms, Crest Syndrome, Cell Transformation, Neoplastic. The study of the Cell Fate Specification Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Cell Fate Specification Pathway has been researched in relation to Cell Proliferation, Cell Differentiation, Cell Cycle, Localization, Neurogenesis. The Cell Fate Specification Pathway complements our catalog of research reagents including antibodies and ELISA kits against NOTCH, WNT, EGFR, SHH, BETA-CATENIN.
Cell Fate Specification Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Cell Fate Specification below!
For more information on how to use Laverne, please read the How to Guide.
We have 2022 products for the study of the Cell Fate Specification Pathway that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.
![Knockout Validated: Notch-1 Antibody (mN1A) [NB100-78486] - Lysates of HeLa human cervical epithelial carcinoma parental cell line and Notch-1 knockout (KO) HeLa cell line. PVDF membrane was probed with 2.0 ug/mL of Mouse Anti-Human Notch-1 Monoclonal Antibody (Catalog # NB100-78486) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog #HAF018). Specific band was detected for Notch-1 at approximately 110 kDa (as indicated) in the parental HeLa cell line, but is not detectable in the knockout HeLa cell line. This experiment was conducted under reducing conditions.](https://images.novusbio.com/fullsize2/Notch-1-Antibody-(mN1A)-Knockout-Validated-NB100-78486-img0011.jpg)
![Western Blot: Notch-1 Antibody (mN1A) [NB100-78486] - Cell extracts from Jurkat (Lane 1) or mouse thymocytes (Lane 2) were analyzed with monoclonal anti-NOTCH1 antibody. The mN1A antibody recognizes both mouse and human 270 kDa full-length NOTCH1 and 110-120 kDa cleaved NOTCH 1 (NICD).](https://images.novusbio.com/fullsize2/Notch-1-Antibody-(mN1A)-Western-Blot-NB100-78486-img0009.jpg)
![Western Blot: NUMB Antibody [NB500-178] - Detection of NUMB isoforms 1 and 2 in A431 whole cell lysate (20 ug) using 0.5 ug/ml of NB500-178. ECL detection: 30 seconds.](https://images.novusbio.com/fullsize2/NUMB-Antibody-Western-Blot-NB500-178-img0005.jpg)
![Immunocytochemistry/Immunofluorescence: Numb Antibody [NB500-178] - Rat FR cells were fixed in 4% paraformaldehyde for 10 minutes and permeabilized in 0.05% Triton X-100 in PBS for 5 minutes. The cells were incubated with (NB500-178) at 1ug/ml overnight at 4C and detected with an anti-rabbit DyLight 488 (Green) at a 1:1000 dilution for 60 minutes. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.](https://images.novusbio.com/fullsize2/Numb-Antibody-Immunocytochemistry-Immunofluorescence-NB500-178-img0009.jpg)
![Western Blot: ERK2 Antibody (6E5) [NBP1-47842] - Analysis of extracts (35ug) from 9 different cell lines by using anti-ERK2 monoclonal antibody.](https://images.novusbio.com/fullsize2/ERK2-Antibody-(6E5)-Western-Blot-NBP1-47842-img0011.jpg)
![Immunohistochemistry-Paraffin: ERK2 Antibody (6E5) [NBP1-47842] - Endometrium tissue within the normal limits using antiMAPK1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min,Dilution 1:50)](https://images.novusbio.com/fullsize2/ERK2-Antibody-(6E5)-Immunohistochemistry-Paraffin-NBP1-47842-img0019.jpg)
![Western Blot: Notch-4 Antibody [NB100-93551] - Analysis of Notch-4 in 1. Jurkat 2. U937 3. WEHI 4. Raw267 cell lysates.](https://images.novusbio.com/fullsize2/Notch-4-Antibody-Western-Blot-NB100-93551-img0007.jpg)
![Immunocytochemistry/Immunofluorescence: Notch-4 Antibody [NB100-93551] - Notch-4 antibody (1:500) was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 20x.](https://images.novusbio.com/fullsize2/Notch-4-Antibody-Immunocytochemistry-Immunofluorescence-NB100-93551-img0005.jpg)
![Western Blot: NME1-NME2 Antibody [NBP1-80992] - Western blot analysis in mouse cell line NIH-3T3, rat cell line NBT-II and rat cell line pC12.](https://images.novusbio.com/fullsize2/NME1-NME2-Antibody-Western-Blot-NBP1-80992-img0011.jpg)
![Immunocytochemistry/Immunofluorescence: NME1-NME2 Antibody [NBP1-80992] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol.](https://images.novusbio.com/fullsize2/NME1-NME2-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-80992-img0010.jpg)
![Immunohistochemistry-Paraffin: p57 Kip2 Antibody [NBP1-89917] - Staining in human placenta and colon tissues using anti-CDKN1C antibody. Corresponding CDKN1C RNA-seq data are presented for the same tissues.](https://images.novusbio.com/fullsize2/p57-Kip2-Antibody-Immunohistochemistry-Paraffin-NBP1-89917-img0014.jpg)
![Western Blot: p57 Kip2 Antibody [NBP1-89917] - Analysis in human placenta tissue.](https://images.novusbio.com/fullsize2/p57-Kip2-Antibody-Western-Blot-NBP1-89917-img0015.jpg)
![Western Blot: SS18L1 Antibody [NBP2-20486] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.](https://images.novusbio.com/fullsize2/SS18L1-Antibody-Western-Blot-NBP2-20486-img0006.jpg)
![Immunocytochemistry/Immunofluorescence: SS18L1 Antibody [NBP2-20486] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.](https://images.novusbio.com/fullsize2/SS18L1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-20486-img0004.jpg)
![Western Blot: DSPP Antibody [NBP2-92546] - Analysis of extracts of various cell lines, using DSPP at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.](https://images.novusbio.com/fullsize2/DSPP-Antibody-Western-Blot-NBP2-92546-img0004.jpg)
![Immunocytochemistry/Immunofluorescence: DSPP Antibody [NBP2-92546] - Analysis of U-2 OS cells using DSPP . Blue: DAPI for nuclear staining.](https://images.novusbio.com/fullsize2/DSPP-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-92546-img0003.jpg)
