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Bone Development Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Bone Development Pathway and Hypertrophy, Fracture, Osteoporosis, Bone Diseases, Neoplasms. The study of the Bone Development Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Bone Development Pathway has been researched in relation to Ossification, Osteoblast Differentiation, Endochondral Ossification, Bone Resorption, Regeneration. The Bone Development Pathway complements our catalog of research reagents including antibodies and ELISA kits against RUNX2, BGLAP, PTH, BMP2, SPP1.

Bone Development Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Bone Development below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1883 products for the study of the Bone Development Pathway that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-77461
Immunocytochemistry/Immunofluorescence: RUNX2/CBFA1 Antibody [NBP1-77461] - RUNX2 antibody was tested in HeLa cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and DyLight 550 (red).Immunohistochemistry: RUNX2/CBFA1 Antibody [NBP1-77461] - Staining of RUNX2 in mouse prostate using DAB with hematoxylin counterstain.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

9 Publications
MAB1419
Saos‑2 human osteosarcoma cell line was stained with Mouse Anti-Human/Rat Osteocalcin Monoclonal Antibody (Catalog # MAB1419, filled histogram) or isotype control antibody (Catalog # <A class=NoLineLink href=Human osteoblasts were stained with Mouse Anti-Human/Rat Osteocalcin Monoclonal Antibody (Catalog # MAB1419, filled histogram) or isotype control antibody (Catalog # <A class=NoLineLink href=

Mouse Monoclonal
Species Human, Rat
Applications IHC, CyTOF-ready, ICC

     2 Reviews

23 Publications
NBP2-35212
SDS-Page: Human PTH Protein [NBP2-35212]


Species Human

355-BM


Species Human, Mouse, Rat

     8 Reviews

148 Publications
AF808
  Osteopontin/OPN  was detected in immersion fixed C2C12 mouse myoblast cell line (left panel,  positive stain) and mouse splenocytes (right panel, negative stain) using  Goat Anti-Mouse Osteopontin/OPN Antigen Affinity-purified Polyclonal Antibody  (Catalog # AF808) at 5 µg/mL for 3 hours at room  temperature. Cells were stained using the NorthernLights™  557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog #  <a class=Recombinant Mouse Osteopontin/OPN (Catalog # <a class=

Goat Polyclonal
Species Mouse
Applications WB, IHC, ELISA(Cap)

     6 Reviews

79 Publications
NBP1-89953
Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining in human skeletal muscle and tonsil tissues. Corresponding DMD RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining of human heart muscle shows strong membranous positivity in myocytes.

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

3 Publications
NB300-164
Dual RNAscope ISH-IHC: Bestrophin 1 Antibody (E6-6) [NB300-164] - Formalin-fixed paraffin-embedded tissue sections of human duodenum were probed for Bestrophin 1 mRNA (ACD RNAScope Probe, catalog # 433181; Fast Red chromogen, ACD catalog # 322360). Adjacent tissue section was processed for immunohistochemistry using mouse anti-human  (Novus Biologicals catalog # NB300-164) at 0.3ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-mouse IgG VisUCyte HRP Polymer Antibody (Catalog # VC001) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue).  IHC signal is confined to cytoplasm.Immunohistochemistry-Paraffin: Bestrophin 1 Antibody (E6-6) [NB300-164] - Bestrophin 1 was detected in immersion fixed paraffin sections of human small intestine using t Mouse Anti-Human Bestrophin 1 Monoclonal Antibody (Catalog # NB300-164) at 5 ug/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to the cell surface and extracellular.

Mouse Monoclonal
Species Human, Porcine, Canine
Applications WB, ICC/IF, IHC

     1 Review

36 Publications
DVE00
 VEGF [HRP] VEGF [HRP]


Species Human

     24 Reviews

508 Publications
NBP1-59322
Western Blot: PTHLH/PTHrP Antibody [NBP1-59322] - HepG2 cell lysate, Antibody Titration: 2.0ug/mlImmunohistochemistry-Paraffin: PTHLH/PTHrP Antibody [NBP1-59322] - Human Lung Alveolar cells (indicated with arrows), 4-8ug/ml.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1705-HH/CF


Species Human, Mouse

6 Publications
291-G1
1 μg/lane of Recombinant Human IGF-I/IGF-1 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 7 kDa.Recombinant Human IGF-I/IGF-1 (Catalog # 291-G1) stimulates proliferation in the MCF-7 human breast cancer cell line. The ED<sub>50</sub> for this effect is 0.3‑1.5 ng/mL.


Species Human

     5 Reviews

137 Publications
H00138428-P01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human

462-TR/CF
1 μg/lane of Recombinant Mouse TRANCE/TNFSF11/RANK L was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 36 kDa.<P align=left>Recombinant Mouse TRANCE/TNFSF11/RANK L (Catalog # 462-TR/CF) induces osteoclast differentiation of the RAW 264.7 mouse monocyte/macrophage cell line. The ED<SUB>50</SUB> for this effect is 5-15 ng/mL in the presence of 2.5 μg/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # <A class=NoLineLink href=


Species Mouse

77 Publications
MAB7547
Western blot shows lysates of Saos‑2 human osteosarcoma cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Osterix/Sp7 Monoclonal Antibody (Catalog # MAB7547) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Osterix/Sp7 was detected in immersion fixed Saos‑2 human osteosarcoma cell line using Mouse Anti-Human Osterix/Sp7 Monoclonal Antibody (Catalog # MAB7547) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red, upper panel; Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, ICC

     1 Review

4014-SP


Species Human

2 Publications
62 Publications
NBP2-66840
Western Blot: FGF R3 Antibody (JM110-33) [NBP2-66840] - Analysis of FGFR3 on different cells lysates using anti-FGFR3 antibody at 1/500 dilution. Positive control: Line 1: 293 Line 2: HepG2Immunocytochemistry/Immunofluorescence: FGF R3 Antibody (JM110-33) [NBP2-66840] - Staining FGFR3 in SH-SY5Y cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

NB110-3638
Western Blot: Alkaline Phosphatase, Placental Antibody (8B6) [NB110-3638] - Analysis of Alkaline Phosphatase (Placental) expression in JAR whole cell lysate.Immunocytochemistry/Immunofluorescence: Alkaline Phosphatase/ALPP Antibody (8B6) [NB110-3638] - Representative montage images are shown for control dissociated DRG culture. (B) Dissociated DRGs cultures exposed to conditioned medium from alkaline phosphatase-expressing rat GRPs. Image collected and cropped by CiteAb from the following publication (eneuro.org/content/4/1/ENEURO.0171-16.2017), licensed under a CC-BY licence.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, Flow

     1 Review

11 Publications
NBP1-89131
Immunocytochemistry/Immunofluorescence: ATRNL1 Antibody [NBP1-89131] - Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.Immunohistochemistry-Paraffin: ATRNL1 Antibody [NBP1-89131] - Staining of human small intestine shows strong cytoplasmic and membranous positivity.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P