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Zollinger-ellison Syndrome: Disease Bioinformatics

Zollinger-ellison Syndrome is a rare condition in which tumors (or gastrinomas) form in a person’s pancreas or upper part of their small intestine. Zollinger-ellison Syndrome can occur at any age but is typically found between the ages of 30-50. Zollinger-ellison Syndrome occurs when the gastrinomas leak the hormone gastrine into the affected area which causes a mass amount of acid to be created in the stomach and, in turn, create peptic ulsers.

Zollinger-ellison Syndrome Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Zollinger-ellison Syndrome below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1550 products for the study of Zollinger-ellison Syndrome that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

H00002520-P01
Other Recombinant Human Gastrin peptide Protein


Species Human

2 Publications
NBP2-48988
Immunohistochemistry: Secretin Antibody [NBP2-48988] - Staining of human duodenum shows strong cytoplasmic positivity in endocrine cells.

Rabbit Polyclonal
Species Human
Applications IHC

MAB2358
    Somatostatin  was detected in immersion fixed paraffin-embedded sections of human pancreas  using Rat Anti-Human/Mouse Somatostatin Monoclonal Antibody (Catalog #  MAB2358) at 5 µg/mL overnight at 4 °C.  Tissue was stained using the Anti-Rat HRP-DAB Cell & Tissue Staining  Kit  (brown; Catalog # <a class=Somatostatin was detected in immersion fixed human embryonic stem cells differentiated to pancreatic cells using Rat Anti-Human Somatostatin Monoclonal Antibody (Catalog # MAB2358) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # <a class=

Rat Monoclonal
Species Human, Mouse
Applications IHC, ICC

NBP2-34260
Immunohistochemistry-Paraffin: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Formalin-fixed, paraffin-embedded human pancreas stained with insulin Monoclonal Antibody (E2-E3)SDS-Page: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260]

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, Flow, ICC/IF

     4 Reviews

NB100-1793
Immunohistochemistry-Paraffin: Pancreatic Polypeptide/PP Antibody [NB100-1793] - (5 ug/ml) staining of paraffin embedded Human Intestine. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Immunohistochemistry-Frozen: Pancreatic Polypeptide/PP Antibody [NB100-1793] - IHC analysis of Pancreatic Polypeptide in mouse adult pancreas tissue. Image courtesy of anonymous customer product review.

Goat Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-Fr

     3 Reviews

10 Publications
NBP1-05163
Immunocytochemistry/Immunofluorescence: VIP Antibody (2) [NBP1-05163] - Staining in human pancreas tissue. Signal is strong in nerves of exocrine part of pancreas. Dilution: 1:100.Immunohistochemistry-Paraffin: VIP Antibody (2)  - BSA Free [NBP1-05163] - Formalin fixed paraffin-embedded human pancreas tissue. Dilution: 1:100

Mouse Monoclonal
Species Human, Rat, Porcine
Applications WB, ELISA, ICC/IF

NBP2-13955
Immunohistochemistry-Paraffin: ELL Antibody [NBP2-13955] - Staining of human testis shows moderate nuclear positivity in cells of seminiferus ducts.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-35641
Western Blot: Cholecystokinin Antibody [NBP1-35641] BrainImmunohistochemistry-Paraffin: Cholecystokinin Antibody [NBP1-35641] - Human Stomach

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

MAB1249
Glucagon was detected in immersion fixed beta TC-6 mouse beta cell insulinoma cell line using 10 µg/mL Human/Mouse Glucagon Monoclonal Antibody (Catalog # MAB1249) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <A class=     beta TC‑6  mouse beta cell insulinoma cell line was stained with Mouse Anti-Human/Mouse  Glucagon Monoclonal Antibody (Catalog # MAB1249, filled histogram) or isotype  control antibody (Catalog # <a class=

Mouse Monoclonal
Species Human, Mouse
Applications CyTOF-ready, ICC, ICFlow

     2 Reviews

3 Publications
NB100-1533
Western Blot: POMC Antibody [NB100-1533] - Western blot analysis of POMC using NB100-1533 at 0.01ug/ml in NIH 3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: POMC Antibody [NB100-1533] - Analysis in human Anterior Pituitary Gland shows vesilulate staining in glandular cells.

Goat Polyclonal
Species Human, Mouse, Porcine
Applications WB, ICC/IF, IHC

6 Publications
AF457
Recombinant Mouse CCL21/6Ckine (Catalog # <A class=NoLineLink href=CCL21/6Ckine was detected in perfusion fixed frozen sections of mouse thymus using Goat Anti-Mouse CCL21/6Ckine Antigen Affinity-purified Polyclonal Antibody (Catalog # AF457) at 5 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Mouse
Applications WB, IHC, CyTOF-ready

     2 Reviews

30 Publications
NB120-14817

Mouse Monoclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

     1 Review

3 Publications
NBP2-00900
Western Blot: Spermine synthase Antibody (3C9) [NBP2-00900] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Spermine synthase (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Spermine synthase.Immunohistochemistry-Paraffin: Spermine synthase Antibody (3C9) [NBP2-00900] - Staining of paraffin-embedded Human tonsil using anti-Spermine synthase mouse monoclonal antibody.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

NBP1-28745
Immunohistochemistry: RAI1 Antibody [NBP1-28745] - Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti- RAI1 used at a dilution of 1:1,000 (1ug/ml). Detection: DABImmunoprecipitation: RAI1 Antibody [NBP1-28745] - Samples: Whole cell lysate (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-RAI1 antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 10 ug/mg lysate. RAI1 was also immunoprecipitated by rabbit anti-RAI1 antibody BL6549, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

Rabbit Polyclonal
Species Human
Applications WB, IHC, IP

NBP2-35213
SDS-Page: Human PTH 1 - 84 a.a Protein [NBP2-35213]


Species Human

NB100-62239
Immunohistochemistry-Paraffin: Pepsinogen I Antibody (8003 (99/12)) [NB100-62239] - Differentiation of pyloric-gland type to fundic glands. (A) HE-stained image, showing proliferation of atypical glands associated with mildly enlarged nuclei. (B) Differentiation into fundic glands (pepsinogen-1). Tumor glands are positive for pepsinogen-1. (C) Differentiation into fundic glands (H,K-ATPase). Similar to pepsinogen-1, H,K-ATPase-positive cells can be seen in tumor glands. From: Mitsuishi T, Hamatani S, Hirooka S, Fukasawa N, Aizawa D, Hara Y, et al. (2017)

Mouse Monoclonal
Species Human
Applications ELISA, IHC-P, RIA

MAB9350
Western Blot: Pepsinogen A Antibody (961902) [MAB9350] - Analysis of human stomach tissue lysate with 2 ug/ml of hPGA-4 Monoclonal Antibody followed by HAF005. A specific band was detected for hPGA-4 at approximately45 kDA (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.Immunohistochemistry: Pepsinogen A Antibody (961902) [MAB9350] - Pepsinogen A was detected in immersion fixed paraffin-embedded sections of human stomach using Pepsinogen A Monoclonal Antibody at 1.7 ug/ml. Tissue was stained using Rat IgG VisUCyte HRP Polymer Antibody (brown) and counterstained with hematoxylin (blue). Specific staining was localized to the cytoplasm in epithelial cells.

Rat Monoclonal
Species Human
Applications WB, IHC, IHC-P

     1 Review

8457-AS


Species Human


Related Genes

Zollinger-ellison Syndrome has been researched against:

Related PTMs

Zollinger-ellison Syndrome has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Zollinger-ellison Syndrome is also known as zollinger-ellison syndrome, pancreatic ulcerogenic tumor syndrome, z e syndrome, gastrinoma, zes.