Submit your image related to Diseases to be featured!

Get Social

Submit your Twitter account related to X-linked Emery-dreifuss Muscular Dystrophy to be featured!

Blogs

Submit your blog on X-linked Emery-dreifuss Muscular Dystrophy to be featured!

Events

Submit your event on X-linked Emery-dreifuss Muscular Dystrophy to be featured!

Videos

Submit your video on X-linked Emery-dreifuss Muscular Dystrophy to be featured!

Charities

Submit your charity on X-linked Emery-dreifuss Muscular Dystrophy to be featured!

X-linked Emery-dreifuss Muscular Dystrophy: Disease Bioinformatics

X-linked Emery- Dreifuss Muscular Dystrophy is a rare disease that causes muscle weakness and heart problems. X-linked Emery-Dreifuss Muscular Dystrophy is most likely caused by a mutation in the GMD gene that causes a deficiency in the protein called Emerin. People with X-linked Emery-Dreifuss Muscular Dystrophy often need to go to physical therapy or have surgery to treat their muscle contractures, and some need to live with a pacemaker.

X-linked Emery-dreifuss Muscular Dystrophy Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on X-linked Emery-dreifuss Muscular Dystrophy below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 531 products for the study of X-linked Emery-dreifuss Muscular Dystrophy that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-87692
Western Blot: Emerin Antibody [NBP1-87692] - Analysis in RT-4 cells transfected with control siRNA, target specific siRNA probe #1 and #2. Remaining relative intensity is presented. Loading control: Anti-GAPDH.Immunocytochemistry/Immunofluorescence: Emerin Antibody [NBP1-87692] - Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear membrane & endoplasmic reticulum.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

5 Publications
NBP2-25151
Western Blot: Lamin A + C Antibody (4C4) [NBP2-25151] - Analysis of different cell lysates using mouse mAb to lamin A/C, NBP2-25151, dilution 1:1,000 in green: [1] protein standard (red), [2] HeLa, [3] HEK293 [4] C6, and [5] NIH-3T3 cell lysates. Two strong bands at 74 and 65kDa correspond to the lamin A and lamin C proteins respectively, detected only in the cells of human origin. NBP2-25151 antibody failed to recognize rat or mouse proteins.Immunocytochemistry/Immunofluorescence: Lamin A + C Antibody (4C4) [NBP2-25151] - Analysis of HeLa cells stained with mouse mAb to lamin A/C, NBP2-25151, dilution 1:2,000 in red, and costained with rabbit pAb to HSP60, dilution 1:5,000, in green. The blue is Hoechst staining of nuclear DNA. NBP2-25151 antibody specifically labels the nuclear lamina, while the HSP60 antibody reveals protein expressed in mitochondria.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

NB120-2928
Western Blot: HSP90 alpha Antibody [NB120-2928] - Analysis of 2-fold serial dilutions of HeLa cell lysate, starting at 10 ug, per well.Immunocytochemistry/Immunofluorescence: HSP90 alpha Antibody [NB120-2928] - Analysis of Heat Shock Protein 86 (HSP86, green) in HeLa cells and NIH3T3 cells. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with a HSP86 polyclonal antibody, at a dilution of 1:100 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 488 goat-anti-rabbit IgG secondary antibody at a dilution of 1:400 for 30 minutes at room temperature. Nuclei (blue) were stained with Hoechst 33342 dye.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

7 Publications
NBP1-87822
Western Blot: Thymopoietin/LAP2 Antibody [NBP1-87822] - Analysis in U2OS cells transfected with control siRNA, target specific siRNA probe #1 and #2, using anti-TMPO antibody. Remaining relative intensity is presented.Immunocytochemistry/Immunofluorescence: Thymopoietin/LAP2 Antibody [NBP1-87822] - Immunofluorescent staining of human cell line A-431 shows localization to nuclear membrane. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Publication
NBP2-59783
Immunocytochemistry/Immunofluorescence: Lamin B1 Antibody (4001) [NBP2-59783] - Staining of A-431 cells showing specific staining of nuclear membrane in green. Microtubule and nuclear probes are visualized in red and blue, respectively (where available). Antibody staining is shown in green.Immunohistochemistry-Paraffin: Lamin B1 Antibody (4001) [NBP2-59783] - Staining of human colon shows nuclear membrane positivity in glandular and connective tissue cells.

Mouse Monoclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP2-13968
Western Blot: Erbin Antibody [NBP2-13968] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10<br/>Lane 2: Human cell line U-2 OSImmunocytochemistry/Immunofluorescence: Erbin Antibody [NBP2-13968] - Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
NBP1-89953
Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining of human tonsil shows no positivity as expected.Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining of human heart muscle shows strong membranous positivity in myocytes.

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

2 Publications
NB120-11433
Western Blot: p97/VCP Antibody (5) [NB120-11433] - Analysis of CA46 cell lysate.Immunocytochemistry/Immunofluorescence: p97/VCP Antibody (5) [NB120-11433] - Analysis of VCP using VCP Monoclonal antibody (5) shows staining in C6 glioma cells. VCP staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing VCP at a dilution of 1:20-1:200 over night at 4C, washed with PBS and incubated with a DyLight-488 conjugated.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     1 Review

1 Publication
NBP2-38442
Immunocytochemistry/Immunofluorescence: BANF1 Antibody [NBP2-38442] - Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.Immunohistochemistry-Paraffin: BANF1 Antibody [NBP2-38442] - Staining in human fallopian tube and pancreas tissues using anti-BANF1 antibody. Corresponding BANF1 RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-02211
Western Blot: LEMD3 Antibody (6C10) [NBP2-02211] Analysis of extracts (35ug) from 9 different cell lines by using anti-LEMD3 monoclonal antibody.Immunocytochemistry/Immunofluorescence: LEMD3 Antibody (6C10) [NBP2-02211] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY LEMD3.

Mouse Monoclonal
Species Human, Canine, Primate
Applications WB, Flow, ICC/IF

NBP2-43834
Western Blot: Lamin B2 Antibody (144) [NBP2-43834] - Non-transfected (-) and transfected (+) HepG2 whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Lamin B2 antibody [144]. The HRP-conjugated anti-mouse IgG antibody (NBP2-19382) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: Lamin B2 Antibody (144) [NBP2-43834] - Analysis of HeLa cells were fixed in 2% paraformaldehyde for 30 min. Red: LMNB2 protein stained by Lamin B2 antibody [144] diluted at 1:1000. Green: alpha Tubulin antibody diluted at 1:1000. Blue: Hoechst 33342 staining. [Images captured by Olympus FV1000 Confocal Laser Scanning Microscope]

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-84956
Western Blot: UBL4A Antibody [NBP1-84956] - Analysis in human cell line U-251 MG.Immunohistochemistry-Paraffin: UBL4A Antibody [NBP1-84956] - Staining of human cerebellum shows cytoplasmic positivity in purkinje cells.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

MAB9096
  MYH7  was detected in immersion fixed paraffin-embedded sections of human heart  using Mouse Anti-Human MYH7 Monoclonal Antibody (Catalog # MAB9096) at  1 µg/mL overnight at 4 °C. Tissue was  stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown;  Catalog # <a class=  Western  blot shows lysates of human skeletal muscle tissue and human heart (atrium)  tissue. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human  MYH7 Monoclonal Antibody (Catalog # MAB9096) followed by HRP-conjugated  Anti-Mouse IgG Secondary Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, IHC

NBP1-83915
Western Blot: LMO7 Antibody [NBP1-83915] - Analysis in human cell lines HeLa and HEK293 using anti-LMO7 antibody. Corresponding LMO7 RNA-seq data are presented for the same cell lines. Loading control: anti-HSP90B1.Immunocytochemistry/Immunofluorescence: LMO7 Antibody [NBP1-83915] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol & actin filaments.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

2 Publications
NBP1-83013
Western Blot: PLEKHM1 Antibody [NBP1-83013] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells)Immunohistochemistry-Paraffin: PLEKHM1 Antibody [NBP1-83013] - Staining of human kidney shows strong cytoplasmic positivity in cells of tubules.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-90306
Western Blot: alpha Sarcoglycan Antibody [NBP1-90306] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: alpha Sarcoglycan Antibody [NBP1-90306] - Staining of human heart muscle shows distinct positivity of intercalated discs in myocytes.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication

Related Genes

X-linked Emery-dreifuss Muscular Dystrophy has been researched against:

Related PTMs

X-linked Emery-dreifuss Muscular Dystrophy has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

X-linked Emery-dreifuss Muscular Dystrophy is also known as Emery-dreifuss Muscular Dystrophy, X-linked, Scapuloperoneal Muscular Dystrophy, X-linked Scapuloperoneal Syndrome.