X-linked Combined Immunodeficiency is an inherited disease that causes the body’s immune system to not function properly. X-linked Combined Immunodeficiency is caused by a mutation on the IL2RG gene on the X-Chromosome. This gene is responsible for making the protein that helps to make lymphocytes, which are cells that help to make antibodies. Without these vital lymphocytes, the body is unable to properly fend off disease. Because it is an X-linked disease, the majority of people with X-linked Combined Immunodeficiency are males who are diagnosed as infants. Symptoms of X-linked Combined Immunodeficiency include opportunistic infections, fungal infection, rashes, diarrhea, fevers, colds, and various other conditions that do not go away with traditional treatment. In most cases, survival is only possible with bone marrow transplant or gene replacement therapy.
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on X-linked Combined Immunodeficiency below!
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We have 2359 products for the study of X-linked Combined Immunodeficiency that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.