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Vitamin B 12 Deficiency: Disease Bioinformatics

Low levels of Vitamin B12 know as Vitamin B12 deficiency typically occurs in people that cannot absorb the vitamin correctly from the foods they eat. Vitamin B12 is essential to make red blood cells, as well as your body’s genetic material and keeps amino acid and homocysteine levels in check. Symptoms of Vitamin B12 deficiency are: weakness, tiredness, rapid heartbeat or breathing, sore tongue and pale skin. If Vitamin B12 deficiency goes untreated it can damage nerve cells which leads to more serious problems.

Vitamin B 12 Deficiency Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Vitamin B 12 Deficiency below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1789 products for the study of Vitamin B 12 Deficiency that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-81610
Western Blot: GIF Antibody [NBP1-81610] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: GIF Antibody [NBP1-81610] - Staining in human stomach and liver tissues using anti-GIF antibody. Corresponding GIF RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

     1 Review

AF7895
Western blot shows lysates of HUVEC human umbilical vein endothelial cells and RPMI 8226 human multiple myeloma cell line. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human/Mouse/Rat Transcobalamin II Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7895) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Transcobalamin II was detected in immersion fixed paraffin-embedded sections of human kidney using Sheep Anti-Human/Mouse/Rat Transcobalamin II Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7895) at 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB, IHC

NBP1-86588
Western Blot: CBL Antibody [NBP1-86588] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)Immunocytochemistry/Immunofluorescence: CBL Antibody [NBP1-86588] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NB100-791
Western Blot: MTR Antibody [NB100-791] - Staining of Hela lysate (RIPA buffer, 1.4E5 cells per lane). Detected by chemiluminescence.Immunohistochemistry-Paraffin: MTR Antibody [NB100-791] - Staining of paraffin embedded Human Adrenal Gland. Steamed antigen retrieval with citratebuffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications WB, IHC, IHC-P

     1 Review

2 Publications
NBP2-37607
Western Blot: MTHFR Antibody (5D3) [NBP2-37607] - Western blot analysis using MTHFR mouse mAb against Rat Heart cell lysate.Immunohistochemistry: MTHFR Antibody (5D3) [NBP2-37607] - Immunohistochemical analysis of paraffin-embedded lung cancer using MTHFR mouse mAb with DAB staining.

Mouse Monoclonal
Species Human, Rat
Applications WB, ELISA, IHC

210-TA
Recombinant Human TNF-alpha  (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.1 µg/lane of Recombinant Human TNF-alpha  was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.


Species Human

     19 Reviews

512 Publications
NB500-418
Western Blot: Transferrin Antibody (HTF-14) [NB500-418] - Analysis using the Azide Free version of NB500-418. Detection of 1. hTransferrin; 5 ug/well (red. con.) 2. hTransferrin; 3 ug/well (red. con.) 3. hTransferrin; 1 ug/well (red. con.) M. Low Range marker 4. hTransferrin; 1 ug/well (non-red. con.) 5. hTransferrin; 3 ug/well (non-red. con.)  6. hTransferrin; 5 ug/well (non-red. con.)

Mouse Monoclonal
Species Human, Porcine, Rabbit
Applications WB, B/N, ELISA

     1 Review

NB600-41532
Western Blot: Albumin Antibody [NB600-41532] - Analysis using the HRP conjugate of NB600-41532. Detection of Albumin in whole mouse liver extracts. Image courtesy of anonymous customer product review.

Goat Polyclonal
Species Mouse
Applications WB, ELISA, ICC/IF

38 Publications
H00002520-P01
SDS-Page: Recombinant Human Gastrin peptide Protein [H00002520-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human

2 Publications
215-GM/CF
1 μg/lane of Recombinant Human GM-CSF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.Recombinant Human GM-CSF (Catalog # 215-IL/CF) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human

208 Publications
NBP2-42388
Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.

Mouse Monoclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-88930
Immunocytochemistry/Immunofluorescence: TNFAIP1 Antibody [NBP1-88930] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoli.Immunohistochemistry-Paraffin: TNFAIP1 Antibody [NBP1-88930] - Staining of human smooth muscle shows moderate cytoplasmic positivity in smooth muscle cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP1-88929
Western Blot: NDUFB3 Antibody [NBP1-88929] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: NDUFB3 Antibody [NBP1-88929] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

AF3700
    Western  blot shows lysates of human, mouse, and rat kidney tissue. PVDF membrane was  probed with 1 µg/mL of Sheep Anti-Human/Mouse/<br>Rat Cubilin Antigen  Affinity-purified Polyclonal Antibody (Catalog # AF3700) followed by  HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=    Simple  Western lane view shows lysates of mouse kidney tissue, loaded at  0.2 mg/mL. A specific band was detected for Cubilin at approximately  500 kDa (as indicated) using 10 µg/mL of Sheep Anti-Human  Cubilin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3700)  followed by 1:50 dilution of HRP-conjugated Anti-Sheep IgG Secondary Antibody  (Catalog # <a class=

Sheep Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

     1 Review

H00000875-M01
Western Blot: CBS Antibody (3E1) [H00000875-M01] - CBS monoclonal antibody (M01), clone 3E1. Analysis of CBS expression in MCF-7.Immunohistochemistry-Paraffin: CBS Antibody (3E1) [H00000875-M01] - Analysis of monoclonal antibody to CBS on formalin-fixed paraffin-embedded human hepatocellular carcinoma. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human, Rat
Applications WB, ELISA, ICC/IF

     1 Review

46 Publications
NBP2-34390

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

     1 Review

NBP2-34260
Immunohistochemistry-Paraffin: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Formalin-fixed, paraffin-embedded human pancreas stained with insulin Monoclonal Antibody (E2-E3)SDS-Page: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260]

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, Flow, ICC/IF

     4 Reviews

236-EG
Recombinant Human EGF (Catalog # 236‑EG) stimulates cell proliferation of the Balb/3T3 mouse embryonic fibroblast cell line. The ED<sub>50</sub> for this effect is 20‑100 pg/mL.1 µg/lane of Recombinant Human EGF was resolved with SDS-PAGE  and visualized by silver staining under reducing (R) conditions, showing a single band at 6 kDa.


Species Human

     10 Reviews

317 Publications

Related Genes

Vitamin B 12 Deficiency has been researched against:

Related PTMs

Vitamin B 12 Deficiency has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Vitamin B 12 Deficiency is also known as Cobalamin Deficiency, Cyanocobalamin Deficiency, Deficiency Of Vitamin B12, Deficiency, Vitamin B12, Vitamin B12 Deficiencies.