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Vasculitides, Hiv-1-associated Cns: Disease Bioinformatics

Human Immunodeficiency Virus (HIV) is similar to other viruses, but there is a key difference. The human body’s immune system can rid itself of most viruses. However HIV is an exception to the rule the human immune system can’t get rid of it. HIV can hide in our cells for long periods of time and it attacks T-cells or CD4 witch are a key part of our immune system used to fight infections and disease. HIV invades them, uses them to make copies of itself, and then destroys them. HIV can destroy so many of the body’s T-cells and CD4 cells that it leaves our body defenseless against infections and diseases. Symptoms of HIV can include fever, chills, night sweats, sore through, and swollen lymph nodes. These can start showing up as early as two to four weeks after a person gets HIV. During this time period the HIV is also easier for the body to transfer to other people. When your T-cell count drops below 200 you will begin to develop infections witch normally wouldn't occur in a person with a healthy immune system. As a result of the cells trying to fight off virus in our body Vacuities may occur. Vacuities refer to a group of disorders which all share a common underlying problem of inflammation of blood vessels. The inflammation can affect any size blood vessel, anywhere in the body. It may affect either arteries and/or veins. The inflammation may be focal, meaning that it affects a single location within a vessel; or it may be widespread, with areas of inflammation spread throughout a particular organ or tissue. When this happens the blood flow is reduced to the inflamed area which can cause damage to the tissue or organ.

Vasculitides, Hiv-1-associated Cns Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Vasculitides, Hiv-1-associated Cns below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2013 products for the study of Vasculitides, Hiv-1-associated Cns that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

Immunocytochemistry: CD8 alpha Antibody (53-6.7) [NBP1-49045] - Analysis of immersion fixed splenocytes. Primary antibody was used at a dilution of 10 ug/ml and incubated for 3 hours at room temperature.Immunohistochemistry-Frozen: CD8 alpha Antibody (53-6.7) [NBP1-49045] - Analysis of CD8+ T cells in allogeneic skin grafted onto a mouse.

Rat Monoclonal
Species Mouse, Rat
Applications Flow, ICC/IF, IHC

     1 Review

5 Publications
Western Blot: NOD2 Antibody (2D9) [NB100-524] - Western Blot Image of anti-NOD2 (2D9) Whole cell protein from THP-1 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2 ug/ml anti-NOD2 in 1% milk, and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: NOD2 Antibody (2D9) [NB100-524] - A431 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-NOD2 (2D9) NB100-524 at a 1:200 dilution overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution. Actin was counterstained with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

     1 Review

12 Publications
Immunohistochemistry-Paraffin: CD68 Antibody (KP1) [NB100-683] - IHC staining of CD68 in human spleen using DAB with hematoxylin counterstain.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

32 Publications
Western Blot: TPPP/p25 Antibody [NBP1-80962] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: TPPP/p25 Antibody [NBP1-80962] - Staining of human cell line U-251 MG shows positivity in focal adhesions.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Western Blot: TMED2 Antibody [NBP1-80963] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells), Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells).Immunocytochemistry/Immunofluorescence: TMED2 Antibody [NBP1-80963] - Staining of human cell line U-2 OS shows positivity in plasma membrane & cytoplasm.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

Western Blot: HLA DQA1 Antibody [NBP1-84550] - Lane 1: Marker [KDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human cell line Daudi.Immunocytochemistry/Immunofluorescence: HLA DQA1 Antibody [NBP1-84550] - Staining of human cell line U-251MG shows positivity in cytoplasm.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Western Blot: Calcium-binding-protein-P22 Antibody [NBP1-33736] - A. 50 ug mouse liver lysate/extract   12 % SDS-PAGEImmunocytochemistry/Immunofluorescence: Calcium-binding-protein-P22 Antibody [NBP1-33736] - Analysis of methanol-fixed HeLa, using antibody at 1:200 dilution.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Publication
Immunohistochemistry: NRSN1 Antibody [NBP2-31844] - liver cancerImmunohistochemistry: NRSN1 Antibody [NBP2-31844] - Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

Immunocytochemistry/Immunofluorescence: CD45 Antibody (30-F11) [NB100-77417] - IF on mouse liver. Image from verified customer review.Immunohistochemistry-Paraffin: CD45 Antibody (30-F11) [NB100-77417] - IHC analysis of formalin fixed and paraffin embedded section of mouse spleen using rat monoclonal CD45 antibody (clone 30-F11) at 1:50 dilution. The antibody generated an expected membrane staining in the red and white pulp spleenocytes of the tested spleen section.

Rat Monoclonal
Species Mouse
Applications WB, Flow, Func

     3 Reviews

14 Publications

Related Genes

Vasculitides, Hiv-1-associated Cns has been researched against:

Related Pathways

Related PTMs

Alternate Names

Vasculitides, Hiv-1-associated Cns is also known as Hiv-1-associated Cns Vasculitis.