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Tyrosinemia, Type I: Disease Bioinformatics

Research of Tyrosinemia, Type I has been linked to Tyrosinemias, Liver Carcinoma, Metabolic Diseases, Carcinoma, Liver Diseases. The study of Tyrosinemia, Type I has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Tyrosinemia, Type I include Excretion, Pathogenesis, Urea Cycle, Fatty Acid Oxidation, Regeneration. These pathways complement our catalog of research reagents for the study of Tyrosinemia, Type I including antibodies and ELISA kits against FUMARYLACETOACETATE HYDROLASE, DELTA-AMINOLEVULINATE DEHYDRATASE, AFP, ALAD, CASP3.

Tyrosinemia, Type I Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Tyrosinemia, Type I below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 779 products for the study of Tyrosinemia, Type I that can be applied to Chromatin Immunoprecipitation, Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-48736
Western Blot: Fumarylacetoacetate hydrolase Antibody [NBP2-48736] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissueImmunocytochemistry/Immunofluorescence: Fumarylacetoacetate hydrolase Antibody [NBP2-48736] - Staining of human cell line Hep G2 shows localization to cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB100-2564
Western Blot: FACA/FANCA Antibody [NB100-2564] - Detection of FANC A in transfected COS1 cell lysate.

Rabbit Polyclonal
Species Human
Applications WB

1 Publication
NBP1-89366
Western Blot: HPD Antibody [NBP1-89366] - Lane 1: Mouse liver tissue lysate Lane 2: Rat liver tissue lysateImmunohistochemistry-Paraffin: HPD Antibody [NBP1-89366] - Staining in human liver and duodenum tissues using anti-HPD antibody. Corresponding HPD RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

MAB1368
 alpha ‑Fetoprotein/AFP was detected in immersion fixed HepG2 human hepatocellular carcinoma cell line using Mouse Anti-Human/Mouse  alpha ‑Fetoprotein/AFP Monoclonal Antibody (Catalog # MAB1368) at 25 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <a class=    HepG2  human hepatocellular carcinoma cell line was stained with Mouse  Anti-Human/Mouse  alpha ‑Fetoprotein/AFP Monoclonal Antibody (Catalog #  MAB1368, filled histogram) or isotype control antibody (Catalog #  <a class=

Mouse Monoclonal
Species Human, Mouse
Applications WB, Simple Western, CyTOF-ready

     3 Reviews

21 Publications
NBP1-89158
Western Blot: ALAD Antibody [NBP1-89158] - Lane 1: Marker  [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.  Lane 2: LiverImmunohistochemistry-Paraffin: ALAD Antibody [NBP1-89158] - Staining in human adrenal gland and pancreas tissues using anti-ALAD antibody. Corresponding ALAD RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human, Rat
Applications WB, Simple Western, IHC

1 Publication
H00002954-M01
Western Blot: GSTZ1 Antibody (1G12) [H00002954-M01] - GSTZ1 monoclonal antibody (M01), clone 1G12. Analysis of GSTZ1 expression in NIH/3T3.Immunocytochemistry/Immunofluorescence: GSTZ1 Antibody (1G12) [H00002954-M01] - Analysis of monoclonal antibody to GSTZ1 on HepG2 cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

NB110-96417
Immunocytochemistry/Immunofluorescence: LRP2 Antibody (CD7D5) [NB110-96417] - Immunofluorescence staining of Megalin in the brush border of the proximal tubule.Immunohistochemistry-Paraffin: LRP2 Antibody (CD7D5) [NB110-96417] - Staining (paraffin-embedded tissue-sections fixed in formalin) of Megalin in the brush border of the proximal tubule.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications ICC/IF, IHC, IHC-Fr

     1 Review

7 Publications
H00023263-M01
Immunohistochemistry-Paraffin: MCF2L Antibody (1D11) [H00023263-M01] - Analysis of monoclonal antibody to MCF2L on formalin-fixed paraffin-embedded human tonsil. Antibody concentration 1 ug/ml.Sandwich ELISA: MCF2L Antibody (1D11) [H00023263-M01] - Detection limit for recombinant GST tagged MCF2L is approximately 0.03ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

NBP1-83910
Western Blot: TRIM26 Antibody [NBP1-83910] - Analysis in human cell line HepG2.Immunohistochemistry-Paraffin: TRIM26 Antibody [NBP1-83910] - Staining of human placenta shows extra cellular positivity.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

2 Publications
NBP1-87408
Western Blot: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Analysis in human liver tissue.Immunocytochemistry/Immunofluorescence: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, ICC/IF

2 Publications
NBP2-13980
Western Blot: FAM126A Antibody [NBP2-13980] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY403173)Immunocytochemistry/Immunofluorescence: FAM126A Antibody [NBP2-13980] - Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-25238
Immunohistochemistry-Paraffin: Tyrosinase Antibody (T311) [NBP2-25238] - Formalin-paraffin melanoma (20X) stained with Tyrosinase Ab (T311).Immunohistochemistry-Paraffin: Tyrosinase Antibody (T311) [NBP2-25238] - Formalin-paraffin melanoma (10X) stained with Tyrosinase Ab (T311).

Mouse Monoclonal
Species Human
Applications Flow, ICC/IF, IHC-P

AF835
Caspase‑3 was detected in immersion fixed Jurkat human acute T cell leukemia cell line stimulated with staurosporin using Human/Mouse Active Caspase‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF835) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rabbit IgG Secondary Antibody (yellow; Catalog # <A class=NoLineLink href=Caspase‑3 was detected in immersion fixed anti-FAS treated Jurkat human acute T cell leukemia cell line using 0.3 µg/mL Human/Mouse Active Caspase‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF835) for 3 hours at room temperature. Cells were stained (red) and counterstained (green). View our protocol for <A class=

Rabbit Polyclonal
Species Human, Mouse
Applications ICC

     9 Reviews

131 Publications
NBP1-89512
Immunocytochemistry/Immunofluorescence: Glycine N-Methyltransferase/GNMT Antibody [NBP1-89512] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol.Immunohistochemistry-Paraffin: Glycine N-Methyltransferase/GNMT Antibody [NBP1-89512] - Staining in human pancreas and colon tissues using anti-GNMT antibody. Corresponding GNMT RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
NBP1-81838
Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838] - Analysis in human cell line SK-MEL-30.Immunohistochemistry-Paraffin: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838] - Staining of human liver shows low expression as expected.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

1 Publication
NBP2-33488
Western Blot: HGD Antibody [NBP2-33488] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissueImmunocytochemistry/Immunofluorescence: HGD Antibody [NBP2-33488] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-58268
Western Blot: Coagulation Factor II/Thrombin Antibody [NBP1-58268] - 721_B tissue lysate at a concentration of 1ug/ml.Immunohistochemistry: Coagulation Factor II/Thrombin Antibody [NBP1-58268] - Analysis of human liver after heat-induced Antigen retrieval. Antibody concentration 5 ug/ml.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

     1 Review

NB100-56503
Western Blot: Cytochrome c Antibody (7H8.2C12) [NB100-56503] - Analysis using the Biotin conjugate of NB100-56503. Detection of Cytochrome C in 15 mgs of HeLa cell lysate using NB100-55775 at 1:1000. A 15 kDa band is detected.Immunocytochemistry/Immunofluorescence: Cytochrome c Antibody (7H8.2C12) [NB100-56503] - p73 was detected in immersion fixed Hela human cell line using Cytochrome C [7H8.2C12] Monoclonal Antibody (Catalog # NB100-56503) at 25 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Staining was observed in the cytoplasm and mitochondria.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

47 Publications

Related PTMs

Tyrosinemia, Type I has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Tyrosinemia, Type I is also known as Deficiency Of Fumarylacetoacetase, Fumarylacetoacetase Deficiency, Hepatorenal Tyrosinemia, Hereditary Tyrosinaemia Type I, Hereditary Tyrosinemia Type I.