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Tyrosinemia, Type I: Disease Bioinformatics

Research of Tyrosinemia, Type I has been linked to Tyrosinemias, Liver Carcinoma, Metabolic Diseases, Carcinoma, Liver Diseases. The study of Tyrosinemia, Type I has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Tyrosinemia, Type I include Excretion, Pathogenesis, Urea Cycle, Fatty Acid Oxidation, Regeneration. These pathways complement our catalog of research reagents for the study of Tyrosinemia, Type I including antibodies and ELISA kits against FUMARYLACETOACETATE HYDROLASE, DELTA-AMINOLEVULINATE DEHYDRATASE, AFP, ALAD, CASP3.

Tyrosinemia, Type I Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Tyrosinemia, Type I below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 746 products for the study of Tyrosinemia, Type I that can be applied to Chromatin Immunoprecipitation, Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-53110
Western Blot: Fumarylacetoacetate hydrolase Antibody [NBP1-53110] - Jurkat cell lysate, concentration 2.5 ug/ml.Immunohistochemistry-Paraffin: Fumarylacetoacetate hydrolase Antibody [NBP1-53110] - Human Liver and Mouse FAH KO liver. Primary Dilution: 1:400

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

NB100-2564
Western Blot: FACA/FANCA Antibody [NB100-2564] - Detection of FANC A in transfected COS1 cell lysate.

Rabbit Polyclonal
Species Human
Applications WB

1 Publication
NBP1-89366
Western Blot: HPD Antibody [NBP1-89366] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissue.  Lane 6: Human tonsil tissueImmunohistochemistry-Paraffin: HPD Antibody [NBP1-89366] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

MAB1368
    Western  blot shows lysates of HepG2 human hepatocellular carcinoma cell line. PVDF  membrane was probed with 0.5 µg/mL of Mouse Anti-Human/Mouse<br> alpha ‑Fetoprotein/AFP Monoclonal Antibody (Catalog # MAB1368) followed  by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=    Western  blot shows lysates of HepG2 human hepatocellular carcinoma parental cell line  and  alpha ‑Fetoprotein/AFP knockout HepG2 cell line (KO). PVDF membrane was probed  with 0.1 µg/mL of Mouse Anti-Human/Mouse  alpha ‑Fetoprotein/AFP  Monoclonal Antibody (Catalog # MAB1368) followed by HRP-conjugated Anti-Mouse  IgG Secondary Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human, Mouse
Applications WB, Simple Western, CyTOF-ready

     3 Reviews

18 Publications
NBP1-89158
Western Blot: ALAD Antibody [NBP1-89158] - Lane 1: Marker  [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.  Lane 2: LiverImmunohistochemistry-Paraffin: ALAD Antibody [NBP1-89158] - Staining of human adrenal gland shows strong cytoplasmic and nuclear positivity in cortical cells.

Rabbit Polyclonal
Species Human, Rat
Applications WB, Simple Western, IHC

1 Publication
H00002954-M01
Western Blot: GSTZ1 Antibody (1G12) [H00002954-M01] - GSTZ1 monoclonal antibody (M01), clone 1G12. Analysis of GSTZ1 expression in NIH/3T3.Immunocytochemistry/Immunofluorescence: GSTZ1 Antibody (1G12) [H00002954-M01] - Analysis of monoclonal antibody to GSTZ1 on HepG2 cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

NB110-96417
Immunocytochemistry/Immunofluorescence: LRP2 Antibody (CD7D5) [NB110-96417] -  Immunofluorescence staining of Megalin in the brush border of the proximal tubule.Immunohistochemistry-Paraffin: LRP2 Antibody (CD7D5) [NB110-96417] -  Staining (paraffin-embedded tissue-sections fixed in formalin) of Megalin in the brush border of the proximal tubule.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications ICC/IF, IHC, IHC-Fr

     1 Review

7 Publications
H00023263-M01
Immunohistochemistry-Paraffin: MCF2L Antibody (1D11) [H00023263-M01] - Analysis of monoclonal antibody to MCF2L on formalin-fixed paraffin-embedded human tonsil. Antibody concentration 1 ug/ml.Sandwich ELISA: MCF2L Antibody (1D11) [H00023263-M01] - Detection limit for recombinant GST tagged MCF2L is approximately 0.03ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

NBP1-83910
Western Blot: TRIM26 Antibody [NBP1-83910] - Analysis in human cell line HepG2.Immunocytochemistry/Immunofluorescence: TRIM26 Antibody [NBP1-83910] - Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

2 Publications
NBP1-87408
Western Blot: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Analysis in human liver tissue.Immunocytochemistry/Immunofluorescence: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, ICC/IF

2 Publications
NBP2-13980
Western Blot: FAM126A Antibody [NBP2-13980] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY403173)Immunocytochemistry/Immunofluorescence: FAM126A Antibody [NBP2-13980] - Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-25238
Immunohistochemistry-Paraffin: Tyrosinase Antibody (T311) [NBP2-25238] - Formalin-paraffin melanoma (20X) stained with Tyrosinase Ab (T311).Immunohistochemistry-Paraffin: Tyrosinase Antibody (T311) [NBP2-25238] - Formalin-paraffin melanoma (10X) stained with Tyrosinase Ab (T311).

Mouse Monoclonal
Species Human
Applications Flow, ICC/IF, IHC-P

NB100-56708
Western Blot: Caspase-3 Antibody (31A1067) - (Pro and Active) [NB100-56708] - Analysis using the Azide Free version of NB100-56708. Detection of Caspase-3 activation in HeLa cells. Cells were treated with 2mM staurosporine for different time periods. Caspase-3 activation is determined by cleavage of procaspase-3.Western Blot: Caspase-3 Antibody (31A1067) - (Pro and Active) [NB100-56708] - Western Blot Image of anti-Caspase 3 (31A1067).  Whole cell protein from Jurkat cells treated with and without 2 uM staurosporine as indicated was separated on a 4-15% gel by SDS-PAGE, transferred to 0.2 um PVDF membrane and blocked in 5% non-fat milk in TBST.  The membrane was probed with 5 ug/ml anti-Caspase 3 in 1% milk, and detected with an anti-mouse HRP secondary antibody using a Femto sensitivity chemiluminescence reagent.  Note the detection of both pro-caspase 3 at 35 kDa and the cleaved active caspase 3 at 15-17 kDa.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, EM

     1 Review

113 Publications
AF6526
Western blot shows lysates of Capan‑1 human pancreatic adenocarcinoma cell line. PVDF Membrane was probed with 1 µg/mL of Human Glycine N-methyltransferase/GNMT Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6526) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB

NBP1-81838
Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838] - Analysis in human cell line SK-MEL-30.Immunohistochemistry-Paraffin: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838] - Staining of human adrenal gland shows moderate cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

1 Publication
NBP2-33488
Western Blot: HGD Antibody [NBP2-33488] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissueImmunocytochemistry/Immunofluorescence: HGD Antibody [NBP2-33488] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-58268
Western Blot: Coagulation Factor II/Thrombin Antibody [NBP1-58268] - 721_B tissue lysate at a concentration of 1ug/ml.Immunohistochemistry: Coagulation Factor II/Thrombin Antibody [NBP1-58268] - Analysis of human liver after heat-induced Antigen retrieval. Antibody concentration 5 ug/ml.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

     1 Review

NB100-56503
Western Blot: Cytochrome c Antibody (7H8.2C12) [NB100-56503] - Analysis using the Biotin conjugate of NB100-56503. Detection of Cytochrome C in 15 mgs of HeLa cell lysate using NB100-55775 at 1:1000. A 15 kDa band is detected.Immunocytochemistry/Immunofluorescence: Cytochrome c Antibody (7H8.2C12) [NB100-56503]

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

46 Publications

Related PTMs

Tyrosinemia, Type I has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Tyrosinemia, Type I is also known as Deficiency Of Fumarylacetoacetase, Fumarylacetoacetase Deficiency, Hepatorenal Tyrosinemia, Hereditary Tyrosinaemia Type I, Hereditary Tyrosinemia Type I.