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Tuberculosis: Disease Bioinformatics

Tuberculosis is a bacterial infection caused by the Mycobacterium tuberculosis bacteria. Tuberculosis is transmitted through the air from person to person, and is therefore contagious. The two major forms of the disease are Latent TB Infection and TB Disease. Latent TB Infection occurs when an individual is infected by breathing in a Mycobacterium tuberculosis bacteria, but the body is able to suppress the bacteria and prevent further growth. Individuals with Latent TB Infection do not exhibit symptoms and are not contagious, but can become symptomatic and contagious if the bacteria become active. TB Disease is the active form of tuberculosis, and common symptoms include a severe cough, chest pain, coughing up blood, weakness, fever, and weight loss. Treatment for tuberculosis includes six to nine months of several drugs, such as isonaizid, rifampin, ethambutol, and pyrazinamide. Tuberculosis is diagnosed through a TB skin test or a blood test, and individuals with Latent TB Infection and TB Disease should seek treatment to prevent further spread of the disease.

Tuberculosis Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Tuberculosis below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2447 products for the study of Tuberculosis that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

210-TA
Recombinant Human TNF-alpha  (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.1 µg/lane of Recombinant Human TNF-alpha  was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.


Species Human

     21 Reviews

527 Publications
285-IF
1 μg/lane of Recombinant Human IFN-gamma  was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 17 kDa.Recombinant Human IFN-gamma  (Catalog # 285‑IF) demonstrates anti-viral activity in HeLa human cervical epithelial carcinoma cells infected with encephalomyocarditis (EMC) virus. The ED<SUB>50</SUB> for this effect is 0.15‑0.75 ng/mL.


Species Human

     8 Reviews

271 Publications
NBP1-19371
Western Blot: CD4 Antibody [NBP1-19371] - CD4 antibody was tested in the following cell lysates: 1) human spleen 2) human tonsil 3) human placenta 4) human kidney 5) human liver 6) mouse spleen 7) mouse placenta 8) rat placenta.Immunocytochemistry/Immunofluorescence: CD4 Antibody [NBP1-19371] - CD4 antibody was tested in Jurkat cells with DyLight 488 (green). Nuclei were counterstained with DAPI (blue).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     7 Reviews

14 Publications
NBP2-67121
Western Blot: Ago2/eIF2C2 Antibody (JF0992) [NBP2-67121] - Analysis of Argonaute 2 on different lysates using anti-Argonaute 2 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: MCF-7Immunocytochemistry/Immunofluorescence: Ago2/eIF2C2 Antibody (JF0992) [NBP2-67121] - Staining Argonaute 2 in AGS cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

NBP1-89366
Western Blot: HPD Antibody [NBP1-89366] - Analysis using Anti-HPD antibody NBP1-89366 (A) shows similar pattern to independent antibody NBP2-32657 (B).Immunohistochemistry-Paraffin: HPD Antibody [NBP1-89366] - Staining in human liver and duodenum tissues using anti-HPD antibody. Corresponding HPD RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

H00030813-R02
Other VSX1 RNAi


Species Human

202-IL
Recombinant Human IL-2 (Catalog # 202-IL) stimulates cell proliferation of the CTLL‑2 mouse cytotoxic T cell line. The ED<SUB>50</SUB> for this effect is 0.05-0.25 ng/mL.1 μg/lane of Recombinant Human IL-2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.


Species Human

     13 Reviews

244 Publications
NBP1-87148
Western Blot: TST Antibody [NBP1-87148] - Analysis in human liver tissue.Immunohistochemistry-Paraffin: TST Antibody [NBP1-87148] - Staining of human kidney.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NBP1-87404
Western Blot: Adenosine Deaminase/ADA Antibody [NBP1-87404] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.Immunocytochemistry/Immunofluorescence: Adenosine Deaminase/ADA Antibody [NBP1-87404] - Staining of human cell line U-2 OS shows localization to plasma membrane & cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

3 Publications
7954-GM/CF


Species Human

1 Publication
6507-IL/CF


Species Human

2 Publications
H00004498-R01
Other Metallothionein-1J RNAi


Species Human

NB100-1813
Western Blot: NCAPG2 Antibody [NB100-1813] - Detection of Human CAP-G2 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CAP-G2 antibody NB100-1813 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.Western Blot: NCAPG2 Antibody [NB100-1813] - Detection of Human CAP-G2 on HeLa whole cell lysate using NB100-1813. CAP-G2 was also IPed by a rabbit anti-CAP-G2 antibody, and CAP-G2 was co-immunoprecipitated by a rabbit anti-CAP-D3 antibody.

Rabbit Polyclonal
Species Human
Applications WB, IP

2 Publications
NBP2-42388
Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.

Mouse Monoclonal
Species Human
Applications WB, IHC, IHC-P

7270-IL/CF


Species Human

NBP2-24916
Western Blot: Catalase Antibody [NBP2-24916] - Analysis in liver lysate of 1) human 2) mouse and 3) rat at 0.1 ug/ml.Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-24916] - Staining of human liver tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

     1 Review

4 Publications
NBP1-77397
Western Blot: HSP60 Antibody [NBP1-77397] - Analysis of extracts from HeLa and COS cells using NBP1-77397 Hsp60 antibody at 1:1000Immunocytochemistry/Immunofluorescence: HSP60 Antibody [NBP1-77397] - Confocal immunofluorescent analysis of HeLa cells using Hsp60 antibody (NBP1-77397, 1:100). An Alexa Fluor 488-conjugated Goat to rabbit IgG was used as secondary antibody (green, A). Actin filaments were labeled with Alexa Fluor 568 phalloidin (red, B). DAPI was used to stain the cell nuclei (blue, C).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, Flow

     4 Reviews


Related Genes

Tuberculosis has been researched against:

Alternate Names

Tuberculosis is also known as tuberculosis, tuberculous abscess, tuberculoma, tb, tuberculoma (finding), kochs disease.