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Triploidy: Disease Bioinformatics

Triploidy is a condition in which an individual has an extra set of chromosomes, which amount to 69 chromosomes in each cell. This may be caused when an egg is fertilized by two sperm or if the sperm or egg has a full set of chromosomes before fertilization. Triploidy occurs in 1-2% of all conceptions, and is fatal to the infant. Most individuals with triploidy are miscarried in early pregnancies or die before or right after birth. Triploidy cannot be treated or cured because of the fatality rate of the disease. Infants who survive after birth have severe birth defects and only live for a few days. Triploidy is not genetic and has no risk factors, but can be diagnosed through a karyotype.

Triploidy Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Triploidy below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1508 products for the study of Triploidy that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.

alpha-Fetoprotein/AFP Antibody (189502) [Unconjugated]
MAB1368
HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human/Mouse alpha ‑Fetoprotein/AFP Monoclonal Antibody (Catalog # MAB1368, filled histogram) or isotype control antibody (Catalog # <a class= Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human/Mouse<br> alpha ‑Fetoprotein/AFP Monoclonal Antibody (Catalog # MAB1368) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human, Mouse
Applications WB, Simple Western, CyTOF-ready

     6 Reviews

23 Publications
p57 Kip2 Antibody
NBP1-89917
Western Blot: p57 Kip2 Antibody [NBP1-89917] - Analysis in human placenta tissue.Immunocytochemistry/Immunofluorescence: p57 Kip2 Antibody [NBP1-89917] - Staining of human cell line U-2 OS shows localization to nucleoplasm, nuclear bodies & cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
FAM188A Antibody
NBP1-88543
Western Blot: FAM188A Antibody [NBP1-88543] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).Immunocytochemistry/Immunofluorescence: FAM188A Antibody [NBP1-88543] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & nuclear membrane.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

Carbonic Anhydrase VIII/CA8 Antibody
NB100-74382

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC

2 Publications
ANKRD1 Antibody
NBP2-14292
Immunocytochemistry/Immunofluorescence: ANKRD1 Antibody [NBP2-14292] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli fibrillar center.Immunohistochemistry-Paraffin: ANKRD1 Antibody [NBP2-14292] - Staining in human heart muscle and testis tissues. Corresponding ANKRD1 RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

n-Myc Antibody (NMYC-1)
NB200-109
Western Blot: n-Myc Antibody (NMYC-1) [NB200-109] - Analysis of n-Myc expression in IMR32 whole cell lysate.Immunocytochemistry: n-Myc Antibody (NMYC-1) [NB200-109] - The n-Myc (NMYC-1) antibody was tested in NTERA2 cells at a 1:50 dilution against Dylight 488 (Green). Actin and nuclei were counterstained against Phalloidin 568 (Red) and DAPI (Blue), respectively.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ChIP, Flow

3 Publications
Pappalysin-1/PAPP-A Antibody [Unconjugated]
AF2487
Western blot shows lysate of human pregnant sera. PVDF membrane was probed with 0.1 µg/mL of Goat Anti-Human Pappalysin‑1/PAPP‑A Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2487) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, IP

3 Publications
Coronin-1a Antibody
NB110-58867
Western Blot: Coronin-1a Antibody [NB110-58867] - Western blot of HL60 Cell extract stained with RPCA-Cor1a, at dilution of 1:10,000. A prominent band running with an apparent SDS-PAGE molecular weight of ~57kDa corresponds to Coronin-1a. Numbers represent positions of molecular weight standards in kDa.Immunocytochemistry/Immunofluorescence: Coronin-1a Antibody [NB110-58867] - Immunocytochemistry of a mixed neuron/glial culture from newborn rat brain stained with NB110-58867 (green) at a dilution of 1:10,000 and NB300-223 (our antibody to vimentin made in chicken at 1:5,000). Blue is nuclear DNA counter stain. Glial cells and fibroblasts stain with vimentin, while microglia alone stain strongly and specifically for Coronin-1a, which can therefore be used as a robust marker of this important cell type.

Rabbit Polyclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

2 Publications
Coagulation Factor II/Thrombin Antibody
NBP1-58268
Western Blot: Coagulation Factor II/Thrombin Antibody [NBP1-58268] - 721_B tissue lysate at a concentration of 1ug/ml.Immunohistochemistry: Coagulation Factor II/Thrombin Antibody [NBP1-58268] - Analysis of human liver after heat-induced Antigen retrieval. Antibody concentration 5 ug/ml.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

     1 Review

TTF2 Antibody (9E751)
H00008458-M06
Western Blot: TTF2 Antibody (1E8) [H00008458-M06] - Analysis of TTF2 expression in NIH/3T3 (Cat # L018V1).Immunocytochemistry/Immunofluorescence: TTF2 Antibody (1E8) [H00008458-M06] - Analysis of monoclonal antibody to TTF2 on HeLa cell. Antibody concentration 10 ug/ml

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

PRB1 Overexpression Lysate (Native)
NBP2-04611
Western Blot: PRB1 Overexpression Lysate (Adult Normal) [NBP2-04611] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PRB1.


Species Human
Recombinant Human Calcium Channel Flower Homolog Protein
H00011094-P01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human
IL-31 RA Antibody [Unconjugated]
AF2769
IL‑31 RA was detected in immersion fixed K562 human chronic myelogenous leukemia cell line using Goat Anti-Human IL‑31 RA Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2769) at 5 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <a class= IL‑31 RA was detected in immersion fixed THP‑1 human acute monocytic leukemia cell line using Goat Anti-Human IL‑31 RA Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2769) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Flow, CyTOF-ready

3 Publications
Myelin Protein Zero Antibody
NB100-1607
Immunocytochemistry/Immunofluorescence: Myelin Protein Zero Antibody [NB100-1607] - Adult sciatic nerve, Po stained (green) can be seen in the myelin and Schwann cell processes surrounding the nodes of Ranvier. In this photomicrograph, rabbit antibodies against LAMP (red), and DAPI (blue) allows visualization of nuclei.

Chicken Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

6 Publications
p53 Antibody (PAb 240)
NB200-103
Western Blot: p53 Antibody (PAb 240) [NB200-103] - Analysis of p53 in MCF7 and HeLa lystates. Image courtesy of anonymous customer product review.Immunocytochemistry/Immunofluorescence: p53 Antibody (PAb 240) [NB200-103] - HeLa cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton X-100. The cells were incubated with anti-p53 (PAb 240) [NB200-103] at a 1:200 dilution overnight at 4C and detected with an anti-mouse DyLight 488 (Green) at a 1:500 dilution. Actin was detected with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, Flow

     3 Reviews

22 Publications
CHM Antibody
NBP1-84954
Immunohistochemistry-Paraffin: CHM Antibody [NBP1-84954] - Staining of human pancreas shows cytoplasmic positivity in exocrine glandular cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

Peptidylglycine alpha-Amidating Monooxygenase/PAM Antibody
NBP2-34075
Western Blot: Peptidylglycine alpha-Amidating Monooxygenase/PAM Antibody [NBP2-34075] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: Peptidylglycine alpha-Amidating Monooxygenase/PAM Antibody [NBP2-34075] - Staining of human cell line U-2 OS shows localization to cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Lymphotoxin [Unconjugated]
8884-LY


Species Human

3 Publications
PCNA Antibody (PC10)
NB500-106
Western Blot: PCNA Antibody (PC10) [NB500-106] - Whole cell protein from human HeLa, A431, mouse Neuro2A and rat PC12 cells was separated on a 4-20% gel by SDS-PAGE, transferred to 0.2 um PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 1.0 ug/mL anti-Histone h3 in block buffer and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: PCNA Antibody (PC10) [NB500-106] - HeLa cells were fixed and permeabilized for 10 minutes using cold (-20C) MeOH. The cells were incubated with anti-PCNA [PC10] at 5 ug/mL overnight at 4C and detected with an anti-mouse IgG Dylight 488 (Green) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ChIP

     4 Reviews

25 Publications

Related Genes

Triploidy has been researched against:

Related Pathways

Triploidy has been linked to:

Related Diseases

Triploidy has been studied in relation to diseases such as:

Related PTMs

Triploidy has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Triploidy is also known as triploidy, chromosome triploidy syndrome, triploidy syndrome, triploid syndrome.