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Syndactyly: Disease Bioinformatics

Research of Syndactyly has been linked to Syndactyly, Congenital Abnormality, Polydactyly, Hypoplasia, Congenital Hand Deformities. The study of Syndactyly has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Syndactyly include Limb Development, Ossification, Pathogenesis, Cell Death, Programmed Cell Death. These pathways complement our catalog of research reagents for the study of Syndactyly including antibodies and ELISA kits against FGFR2, GJA1, SHH, HOXD13, TP63.

Syndactyly Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Syndactyly below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1133 products for the study of Syndactyly that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.

NBP2-00932
Western Blot: FGF R2 Antibody (5C5) [NBP2-00932] - Analysis of FGF R2 in HEK293T cells (left, control) and HEK293T cells overexpressing FGF R2 (right) using anti-FGF R2 antibody. Image from verified customer review.Immunocytochemistry/Immunofluorescence: FGFR2 Antibody (5C5) [NBP2-00932] Staining of COS7 cells transiently transfected by pCMV6-ENTRY FGFR2.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

     1 Review

1845-SH/CF
1 μg/lane of Recombinant Human Sonic Hedgehog/Shh (C24II), N-Terminus was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 22 kDa.Recombinant Human Sonic Hedgehog/Shh (C24II), N-Terminus (Catalog #<br>1845-SH/CF) induces alkaline phosphatase production by the C3H10T1/2 mouse embryonic fibroblast cell line. The ED<sub>50</sub> for this effect is 0.1‑0.4 μg/mL.


Species Human

27 Publications
NBP1-52149
Immunohistochemistry-Paraffin: HOXD13 Antibody [NBP1-52149] - Staining of Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications IHC, IHC-P, PEP-ELISA

1 Publication
NBP2-33090

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

1 Publication
423-F8
Recombinant Human/Mouse FGF-8b (Catalog # 423-F8) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED<sub>50</sub> for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin.1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.


Species Human, Mouse

     2 Reviews

39 Publications
314-BP
1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.<p style=Recombinant Human BMP-4 (Catalog #<BR>314-BP/CF) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED<SUB>50</SUB> for this effect is 2.5-15 ng/mL.


Species Human

     3 Reviews

293 Publications
NBP1-80740
Immunocytochemistry/Immunofluorescence: DHCR7 Antibody [NBP1-80740] - Immunofluorescent staining of human cell line CACO-2 shows localization to endoplasmic reticulum. Antibody staining is shown in green.Immunohistochemistry-Paraffin: DHCR7 Antibody [NBP1-80740] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

AF3690
Western blot shows lysates of mouse embryo tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse GLI‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3690) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=GLI‑3 was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line using Human/Mouse GLI‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3690) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (yellow; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human, Mouse
Applications WB, ChIP, ICC

     4 Reviews

28 Publications
NBP1-77181
Western Blot: FRAS1 (Fraser syndrome 1) Antibody [NBP1-77181] - FRAS1 (Fraser syndrome 1) Antibody A-20 cell lysate with FRAS1 antibody at (A) 0.5 and (B) 1ug/mL.Immunocytochemistry/Immunofluorescence: FRAS1 (Fraser syndrome 1) Antibody [NBP1-77181] - FRAS1 (Fraser syndrome 1) Antibody A-20 cells with FRAS1 antibody at 20 ug/mL.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ELISA, ICC/IF

NBP2-37364
Western Blot: Twist-1 Antibody (10E4E6) [NBP2-37364] - Analysis using TWIST1 mouse mAb against NIH/3T3 (1), JURKAT (2), HELA (3), A549 (4), RAJI (5) and OCM-1 (6) cell lysate.Immunocytochemistry: Twist-1 Antibody (10E4E6) [NBP2-37364] - Analysis of Hela cells using TWIST1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ELISA, Flow

NBP2-14013
Western Blot: SHFM3 Antibody [NBP2-14013] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: SHFM3 Antibody [NBP2-14013] - Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-85571
Western Blot: CKAP4/p63 Antibody [NBP1-85571] - Analysis using Anti-CKAP4 antibody NBP1-85571 (A) shows similar pattern to independent antibody NBP1-85572 (B).Immunohistochemistry-Paraffin: CKAP4/p63 Antibody [NBP1-85571] - Staining of human cerebral cortex using Anti-CKAP4 antibody.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

355-BM/CF


Species Human, Mouse, Rat

126 Publications
AF1589
  Western  blot shows lysates of human bone marrow and mouse bone marrow. PVDF membrane  was probed with 2 µg/mL of Goat Anti-Mouse SOST/Sclerostin Antigen  Affinity-purified Polyclonal Antibody <br>(Catalog # AF1589) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=SOST/Sclerostin was detected in immersion fixed frozen sections of mouse embryo (adrenal gland) using Goat Anti-Mouse SOST/Sclerostin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1589) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Mouse
Applications WB, IHC

     3 Reviews

32 Publications
NBP2-24482
Western Blot: UVRAG Antibody [NBP2-24482] - Analysis of UVRAG in human heart lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse heart and 4) rat heart using this antibody at 0 ug/ml, 0.5 ug/ml and 0.5 ug/ml, respectively.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB

6057-NG
BG01V human embryonic stem cells were cultured in Mouse Embryonic Fibroblast Conditioned Media supplemented with FGF basic (5 ng/mL). Stem cells were driven into early cells of the neuroectoderm using a 3 day incubation in recombinant human Noggin (25 µg/mL) from either R&D Systems (Lot 1, Lot 2; Catalog #<br>6057-NG) or from two separate competitors (Competitor 1, Competitor 2). Control cells were not incubated in Noggin (No Noggin). The cells were stained for the early ectoderm marker, Otx2, and the neuroectoderm marker, SOX1. (A) Representative images of SOX1 (green), Otx2 (red), and DAPI (blue) staining in embryonic stem cells differentiated with Noggin from R&D Systems or Noggin from Competitor 2. (B) SOX1+ clusters were quantified under each of the indicated culture conditions. Cells treated with R&D Systems Noggin showed an increase in SOX1+ cells compared to both untreated and competitor-treated cells. R&D Systems Noggin showed consistent differentiation across the lots tested. BG01V human embryonic stem cells are licensed from ViaCyte, Inc.


Species Human

     4 Reviews

86 Publications
NBP1-52149
Immunohistochemistry-Paraffin: HOXD13 Antibody [NBP1-52149] - Staining of Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications IHC, IHC-P, PEP-ELISA

1 Publication
NBP2-00932
Western Blot: FGF R2 Antibody (5C5) [NBP2-00932] - Analysis of FGF R2 in HEK293T cells (left, control) and HEK293T cells overexpressing FGF R2 (right) using anti-FGF R2 antibody. Image from verified customer review.Immunocytochemistry/Immunofluorescence: FGFR2 Antibody (5C5) [NBP2-00932] Staining of COS7 cells transiently transfected by pCMV6-ENTRY FGFR2.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

     1 Review

AF3690
Western blot shows lysates of mouse embryo tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse GLI‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3690) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=GLI‑3 was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line using Human/Mouse GLI‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3690) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (yellow; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human, Mouse
Applications WB, ChIP, ICC

     4 Reviews

28 Publications
1845-SH/CF
1 μg/lane of Recombinant Human Sonic Hedgehog/Shh (C24II), N-Terminus was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 22 kDa.Recombinant Human Sonic Hedgehog/Shh (C24II), N-Terminus (Catalog #<br>1845-SH/CF) induces alkaline phosphatase production by the C3H10T1/2 mouse embryonic fibroblast cell line. The ED<sub>50</sub> for this effect is 0.1‑0.4 μg/mL.


Species Human

27 Publications
NBP2-33090

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

1 Publication
423-F8
Recombinant Human/Mouse FGF-8b (Catalog # 423-F8) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED<sub>50</sub> for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin.1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.


Species Human, Mouse

     2 Reviews

39 Publications
314-BP
1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.<p style=Recombinant Human BMP-4 (Catalog #<BR>314-BP/CF) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED<SUB>50</SUB> for this effect is 2.5-15 ng/mL.


Species Human

     3 Reviews

293 Publications
NBP1-80740
Immunocytochemistry/Immunofluorescence: DHCR7 Antibody [NBP1-80740] - Immunofluorescent staining of human cell line CACO-2 shows localization to endoplasmic reticulum. Antibody staining is shown in green.Immunohistochemistry-Paraffin: DHCR7 Antibody [NBP1-80740] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

AF853
<P align=left>GDF‑5 was detected in immersion fixed frozen sections of mouse embyro (12 d.p.c.) using 15 µg/mL Goat Anti-Mouse GDF‑5 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF853) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Mouse
Applications WB, IHC

4 Publications
AF1589
  Western  blot shows lysates of human bone marrow and mouse bone marrow. PVDF membrane  was probed with 2 µg/mL of Goat Anti-Mouse SOST/Sclerostin Antigen  Affinity-purified Polyclonal Antibody <br>(Catalog # AF1589) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=SOST/Sclerostin was detected in immersion fixed frozen sections of mouse embryo (adrenal gland) using Goat Anti-Mouse SOST/Sclerostin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1589) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Mouse
Applications WB, IHC

     3 Reviews

32 Publications
NBP2-14013
Western Blot: SHFM3 Antibody [NBP2-14013] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: SHFM3 Antibody [NBP2-14013] - Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-77181
Western Blot: FRAS1 (Fraser syndrome 1) Antibody [NBP1-77181] - FRAS1 (Fraser syndrome 1) Antibody A-20 cell lysate with FRAS1 antibody at (A) 0.5 and (B) 1ug/mL.Immunocytochemistry/Immunofluorescence: FRAS1 (Fraser syndrome 1) Antibody [NBP1-77181] - FRAS1 (Fraser syndrome 1) Antibody A-20 cells with FRAS1 antibody at 20 ug/mL.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ELISA, ICC/IF

NBP2-37364
Western Blot: Twist-1 Antibody (10E4E6) [NBP2-37364] - Analysis using TWIST1 mouse mAb against NIH/3T3 (1), JURKAT (2), HELA (3), A549 (4), RAJI (5) and OCM-1 (6) cell lysate.Immunocytochemistry: Twist-1 Antibody (10E4E6) [NBP2-37364] - Analysis of Hela cells using TWIST1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ELISA, Flow

NBP1-85571
Western Blot: CKAP4/p63 Antibody [NBP1-85571] - Analysis using Anti-CKAP4 antibody NBP1-85571 (A) shows similar pattern to independent antibody NBP1-85572 (B).Immunohistochemistry-Paraffin: CKAP4/p63 Antibody [NBP1-85571] - Staining of human cerebral cortex using Anti-CKAP4 antibody.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P


Related PTMs

Syndactyly has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Syndactyly is also known as Symphalangism, Symphalangy, Syndactylia, Syndactylias, Syndactylies.