Sudden Unexplained Death In Epilepsy: Disease Bioinformatics
Epilepsy is defined as a diverse set of neurological disorders characterized by seizures. These seizures occur due to abnormal electrical activity in the brain. Factors that may lead to epilepsy include, but are not limited to, brain trauma, gene mutations, strokes, brain cancer, and extensive drug and alcohol use. Seizures occur due to a large release of glutamate, which causes a spread of excitation throughout the brain, which propagates the electrical signal and can lead to neuronal death. Sudden Unexpected Death in Epilepsy is a non-accidental death in a person with epilepsy, who was otherwise in a usual state of health. It accounts for 7-17% of deaths of people with epilepsy. No other of cause of death can be found when sudden unexpected death in epilepsy occurs, but patients with other neurological diseases and those who experience tonic-clonic seizures have a higher risk of occurrence. The death is not caused by status epilepticus, which is a prolonged life-threatening seizure episode. About 50 million people have epilepsy, with 80% of that population located in developing countries. It is possible to control epilepsy with medicine, but many cases may require surgery in order to relieve symptoms.
Sudden Unexplained Death In Epilepsy Bioinformatics Tool
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