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Spastic Paraplegia: Disease Bioinformatics

Research of Spastic Paraplegia has been linked to Paraplegia, Spastic Paraplegia, Hereditary, Muscle Spasticity, Neurodegenerative Disorders, Atrophy. The study of Spastic Paraplegia has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Spastic Paraplegia include Pathogenesis, Transport, Cell Adhesion, Localization, Translation. These pathways complement our catalog of research reagents for the study of Spastic Paraplegia including antibodies and ELISA kits against APP, HSPD1, KIF5A, L1CAM, PLP1.

Spastic Paraplegia Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Spastic Paraplegia below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 821 products for the study of Spastic Paraplegia that can be applied to Western Blot, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-90230
Western Blot: Spastin Antibody [NBP1-90230] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-550Immunocytochemistry/Immunofluorescence: Spastin Antibody [NBP1-90230] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.

Rabbit Polyclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

H00051062-M03
Western Blot: SPG3A Antibody (1B9) [H00051062-M03] - Analysis of SPG3A expression in PC-12 (Cat # L012V1).Western Blot: SPG3A Antibody (1B9) [H00051062-M03] - Analysis of SPG3A expression in IMR-32 (Cat # L008V1).

Mouse Monoclonal
Species Human, Rat
Applications WB, ELISA

NBP1-87781
Western Blot: Myelin PLP Antibody [NBP1-87781] - Analysis in control (vector only transfected HEK293T lysate) and pLP1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining of human cerebral cortex shows distinct positivity in neuropil.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

     1 Review

1 Publication
NBP2-02149
Western Blot: L1CAM Antibody (2A6) [NBP2-02149] Analysis of extracts (35ug) from 9 different cell lines by using anti-L1CAM monoclonal antibody.Immunocytochemistry/Immunofluorescence: L1CAM Antibody (2A6) [NBP2-02149] - Staining of COS7 cells.

Mouse Monoclonal
Species Human, Monkey
Applications WB, Flow, ICC/IF

NBP2-01860
Western Blot: SPG7 Antibody (1C1) [NBP2-01860] - Human tissue.Immunocytochemistry/Immunofluorescence: SPG7 Antibody (1C1) [NBP2-01860] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY SPG7.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

1 Publication
NBP1-82143
Immunocytochemistry/Immunofluorescence: SPG11 Antibody [NBP1-82143] - Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.Immunohistochemistry-Paraffin: SPG11 Antibody [NBP1-82143] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP1-02459
Immunohistochemistry-Paraffin: Hsp90B2P Antibody [NBP1-02459] - Staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.Immunohistochemistry-Paraffin: Hsp90B2P Antibody [NBP1-02459] - Human kidney

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, IHC

NBP1-47203
Western Blot: SPG20 Antibody [NBP1-47203] - (2ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunocytochemistry/Immunofluorescence: SPG20 Antibody [NBP1-47203] - (2ug/ml) staining of methanol-fixed HeLa before (left) and after (right) introduction of siRNA.

Goat Polyclonal
Species Human
Applications WB, ICC/IF, PEP-ELISA

1 Publication
NBP1-85344
Western Blot: Kinesin 5A Antibody [NBP1-85344] - Analysis in human cerebral cortex tissue.Immunocytochemistry/Immunofluorescence: Kinesin 5A Antibody [NBP1-85344] - Staining of mouse hippocampus shows positivity in a subset of neurons.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-13075
Western Blot: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - Western blot analysis in cell lysates from HEK-APP SWE/BACE1 cells probed with an antibody against the C-terminus of APP (Lanes 1 and 2) and beta Amyloid  (MOAB-2, Lanes 3 and 4).  Beta Amyloid (MOAB-2) does not detect APP (from PMID: 22423893).Immunocytochemistry/Immunofluorescence: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - Immunofluorescent detection of beta Amyloid with MOAB-2 in the subiculim of 1-, 2- and 4- month old 5xFAD mice.  Scale bar 20 um (from PMID: 22423893).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

9 Publications
AF5724
Western blot shows lysates of human, mouse, and rat brain tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse/Rat Peroxiredoxin 5 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5724) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=    Peroxiredoxin 5  was detected in immersion fixed A549 human lung carcinoma cell line using  Goat Anti-Human/Mouse/Rat Peroxiredoxin 5 Antigen Affinity-purified  Polyclonal Antibody (Catalog # AF5724) at 10 µg/mL for 3  hours at room temperature. Cells were stained using the  NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody  (red; Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC

NBP2-27461
Western Blot: PDXP Antibody [NBP2-27461] - 0.1 ug/ml staining of Mouse (A) and Rat (B) Brain lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Western Blot: PDXP Antibody [NBP2-27461] - NBP2-27461 (0.1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, PEP-ELISA

1 Publication
NBP1-59322
Western Blot: PTHLH/PTHrP Antibody [NBP1-59322] - HepG2 cell lysate, Antibody Titration: 2.0ug/mlImmunohistochemistry-Paraffin: PTHLH/PTHrP Antibody [NBP1-59322] - Human Lung Alveolar cells (indicated with arrows), 4-8ug/ml.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-59312

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

H00008086-M02
Western Blot: AAAS Antibody (5A1) [H00008086-M02] - AAAS monoclonal antibody (M02), clone 5A1. Analysis of AAAS expression in NIH/3T3.Immunohistochemistry-Paraffin: AAAS Antibody (5A1) [H00008086-M02] - Analysis of monoclonal antibody to AAAS on formalin-fixed paraffin-embedded human prostate. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, IHC-P

NBP1-77397
Western Blot: HSP60 Antibody [NBP1-77397] - Western blot analysis of extracts from HeLa and COS cells using NBP1-77397 Hsp60 antibody at 1:1000Immunocytochemistry/Immunofluorescence: HSP60 Antibody [NBP1-77397] - Confocal immunofluorescent analysis of HeLa cells using Hsp60 antibody (NBP1-77397, 1:100). An Alexa Fluor 488-conjugated Goat to rabbit IgG was used as secondary antibody (green, A). Actin filaments were labeled with Alexa Fluor 568 phalloidin (red, B). DAPI was used to stain the cell nuclei (blue, C).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

     4 Reviews

NB100-885
Immunohistochemistry: Als2 Antibody [NB100-885] - IHC staining of Als2 in paraffin embedded Human Cortex using NB100-885 at 3.8ug/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications WB, ICC/IF, IHC

2 Publications
NBP2-38445
Western Blot: RNF6 Antibody [NBP2-38445] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Negative Control.  Lane 3: Overexpression lysateImmunocytochemistry/Immunofluorescence: RNF6 Antibody [NBP2-38445] - Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-89273
Western Blot: SPG21 Antibody [NBP1-89273] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: SPG21 Antibody [NBP1-89273] - Staining of human gallbladder shows cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC