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Sotos' Syndrome: Disease Bioinformatics

Research of Sotos' Syndrome has been linked to Gigantism, Growth Disorders, Brain Diseases, Macrocephaly, Craniofacial Abnormalities. The study of Sotos' Syndrome has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Sotos' Syndrome include Feeding Behavior, Pathogenesis, Secretion, Long-term Memory, Methylation. These pathways complement our catalog of research reagents for the study of Sotos' Syndrome including antibodies and ELISA kits against GROWTH HORMONE, SOMATOMEDIN, N2, N3, N1.

Sotos' Syndrome Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Sotos' Syndrome below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1591 products for the study of Sotos' Syndrome that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.

Western Blot: KMT3B/NSD1 Antibody (4F1) [H00064324-M08] - NSD1 monoclonal antibody (M08), clone 4F1. Western Blot analysis of NSD1 expression in human uterus myoma.

Mouse Monoclonal
Species Human
Applications WB, ELISA

1 Publication
Immunocytochemistry/Immunofluorescence: BBS9 Antibody [NBP1-88927] Staining of human cell line A-431 shows positivity in nucleus but not nucleoli, plasma membrane & cytoplasm.Immunohistochemistry-Paraffin: BBS9 Antibody [NBP1-88927] - Staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

3 Publications
Western Blot: SPANXB1 Antibody [H00728695-B01P] - Analysis of SPANXB1 expression in transfected 293T cell line by SPANXB1 polyclonal antibody.  Lane 1: SPANXB1 transfected lysate(11.33 KDa). Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: SPANXB1 Antibody [H00728695-B01P] - Analysis of purified antibody to SPANXB1 on Hs 181.Tes cell. (antibody concentration 10 ug/ml)

Mouse Polyclonal
Species Human
Applications WB, ELISA, ICC/IF

Western Blot: MS4A1/CD20 Antibody (AISB12) [NBP1-43435] - Immunoblot of Balb/c thymus (lane 1) and A20 (lane 2) cell lysates with Anti-Mouse CD20 Purified.Flow Cytometry: MS4A1/CD20 Antibody (AISB12) [NBP1-43435] - Staining of BALB/c splenocytes with Anti-Mouse CD19 Alexa Fluor (R) 647 and 1.0 micrograms conjugated anti-Mouse CD20 Purified followed by Anti-Rat IgG PE. Quadrant lines represent Rat IgG2a isotype control staining levels and cells in the lymphocyte gate were used for analysis.

Rat Monoclonal
Species Human, Mouse
Applications WB, Flow

3 Publications
Western Blot: nNOS Antibody [NB100-858] - Western blot analysis of nNOS in human muscle extracts (RIPA buffer, 35ug total protein per lane) using NB100-858 at 0.3 ug/ml.

Goat Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

     1 Review

8 Publications
Western Blot: CREB [p Ser121] Antibody [NB100-410] - Detection of phospho-CREB in human HEK 293T cells. Top panel: probed with NB 100-410. Bottom panel: probed with CREB antibody. Lanes 2 and 4 treated with lambda phosphatase, lanes 3 and 4 treated with 0.2mM H202.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IP

6 Publications
    Human peripheral  blood mononuclear cells (PBMCs) were stained with Recombinant Mouse Anti-Human CD3 epsilon   Alexa Fluor® 700‑conjugated Monoclonal Antibody (Catalog # <a class=

Species Human
Applications Flow

Western Blot: WHSC1 Antibody [NBP1-82633] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)Immunocytochemistry/Immunofluorescence: WHSC1 Antibody [NBP1-82633] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

3 Publications
Western Blot: SLC17A5 Antibody [NBP2-20383] - Sample (30 ug of whole cell lysate) A: Jurkat 10% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SLC17A5 Antibody [NBP2-20383] - Sample: HepG2 cells were fixed in -20C 100% MeOH for 5 min. Green: SLC17A5 protein stained by SLC17A5 antibody diluted at 1:500. Blue: Hoechst 33343 staining.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Western Blot: NSD3 Antibody [NBP1-04991] - Detection of NSD3 (isoform 3) in HeLa nuclear extracts using NBP1-04991.

Rabbit Polyclonal
Species Human
Applications ICC/IF (-), WB

     1 Review

1 Publication
Immunohistochemistry: SUR1 Antibody [19600002] - Most normal tissues exhibited moderate to strong cytoplasmic expression. Membranous staining pattern was seen in the intestinal tissues. Strong cytoplasmic immunoreactivity was observed in salivary gland, exocrine pancreas, skeletal muscle and non-follicle cells of lymph node. Purkinje cells and adrenal cortical cells demonstrated strong nuclear positivity. Malignant tissues generally displayed weak to moderate cytoplasmic expression. Strong membranous staining pattern was observed in colo-rectal cancers. Nuclear staining was mainly seen in non-Hodgkin's lymphomas, urothelial cancers and malignant gliomas.  Image and statement courtesy of the Human Protein Atlas (HPA).Immunohistochemistry: SUR1 Antibody [19600002] - Strong membranous staining pattern observed in colo-rectal cancers by immunohistochemistry.  Image is provided courtesy of the Swedish Human Proteome Resource (HPR) Center.

Rabbit Polyclonal
Species Human
Applications ELISA, IHC, IHC-P

Related Genes

Sotos' Syndrome has been researched against:

Related PTMs

Sotos' Syndrome has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Sotos' Syndrome is also known as Cerebral Giant, Cerebral Gigantism, Cerebral Gigantism Syndrome, Gigantism, Cerebral, Soto Syndrome.