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Skin Abnormalities: Disease Bioinformatics

Research of Skin Abnormalities has been linked to Congenital Abnormality, Dermatologic Disorders, Aplasia, Nos, Congenital Heart Defects, Dysplasia. The study of Skin Abnormalities has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Skin Abnormalities include Pathogenesis, Pigmentation, Localization, Aging, Skin Development. These pathways complement our catalog of research reagents for the study of Skin Abnormalities including antibodies and ELISA kits against RAS, TIGHT SKIN, FOXL2, BRAF, ELN.

Skin Abnormalities Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Skin Abnormalities below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 736 products for the study of Skin Abnormalities that can be applied to Flow Cytometry, Chromatin Immunoprecipitation, Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-47833
Western Blot: MEK1 Antibody (1F5) [NBP1-47833] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MEK1(Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MEK1.Immunocytochemistry/Immunofluorescence: MEK1 Antibody (1F5) [NBP1-47833] Staining of COS7 cells transiently transfected by pCMV6-ENTRY MEK1.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

     1 Review

1 Publication
NBP1-47836
Western Blot: MEK2 Antibody (8G6) [NBP1-47836] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MEK2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MEK2.Immunohistochemistry-Paraffin: MEK2 Antibody (8G6) [NBP1-47836] - Staining of paraffin-embedded Human pancreas tissue using anti-MEK2 mouse monoclonal antibody.

Mouse Monoclonal
Species Human
Applications WB, Flow, IHC

NBP2-42864
Western Blot: HRAS Antibody [NBP2-42864] - Various whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membranes were blotted with H-Ras antibody diluted at 1:500.Immunocytochemistry/Immunofluorescence: HRAS Antibody [NBP2-42864] - Analysis of paraformaldehyde-fixed HeLa, using H-Ras antibody at 1:200 dilution.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP1-89942
Western Blot: B-Raf Antibody [NBP1-89942] - Analysis in human cell line MOLT-4.Immunohistochemistry-Paraffin: B-Raf Antibody [NBP1-89942] - Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in distal tubules.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

1 Publication
NB100-1277
Western Blot: FOXL2 Antibody [NB100-1277] - Staining of Human (A) and Mouse (B) Ovary lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: FOXL2 Antibody [NB100-1277] - Staining of paraffin embedded Human Adrenal Gland. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human, Mouse, Ferret
Applications WB, ChIP, ICC/IF

     1 Review

28 Publications
H00003845-M01
Western Blot: KRAS Antibody (3B10-2F2) [H00003845-M01] - KRAS monoclonal antibody (M01), clone 3B10-2F2 Analysis of KRAS expression in HeLa.Immunocytochemistry/Immunofluorescence: KRAS Antibody (3B10-2F2) [H00003845-M01] - Analysis of monoclonal antibody to KRAS on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

     1 Review

10 Publications
NBP2-34270
Immunohistochemistry-Paraffin: Cytokeratin 14 Antibody (LL002) [NBP2-34270] - Formalin-fixed, paraffin-embedded prostate stained with Cytokeratin 14 Monoclonal Antibody (LL002).Immunohistochemistry-Paraffin: Cytokeratin 14 Antibody (LL002) [NBP2-34270] - Formalin-fixed, paraffin-embedded human prostate (10X) stained with Cytokeratin 14 MAb (LL002).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

NB100-2387
Western Blot: ZMPSTE24 Antibody [NB100-2387] - Detection of ZMPSTE24 in human testis.Immunocytochemistry/Immunofluorescence: ZMPSTE24 Antibody [NB100-2387] - analysis of ZMPSTE24 in A549 cells using anti-ZMPSTE24 antibody. Image from verified customer review.

Rabbit Polyclonal
Species Human, Mouse, Zebrafish
Applications WB, ICC/IF

     1 Review

2 Publications
NBP1-87528
Immunocytochemistry/Immunofluorescence: Filaggrin Antibody [NBP1-87528] - Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.Immunohistochemistry-Paraffin: Filaggrin Antibody [NBP1-87528] - Analysis in human skin and kidney tissues using Anti-FLG antibody. Corresponding FLG RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP2-25151
Western Blot: Lamin A + C Antibody (4C4) [NBP2-25151] - Stripe blots of crude HeLa cell extract. Note two strong clean bands at 74 kDa and 64 kDa, corresponding to Lamin A and C, in lane 6. Lane 5 was stained with an antibody to Enolase 1. Lanes 3 and 4 were stained with NBP2-25142, the monoclonal antibody to all six Actin isotypes. Molecular weights of each protein are as indicated.Immunocytochemistry/Immunofluorescence: Lamin A + C Antibody (4C4) [NBP2-25151] - HeLa cells staing with NBP2-25151 (red), and counterstained with chicken polyclonal antibody to Vimentin NB300-223 (green) and DNA (blue). NBP2-25151 reveals strong nuclear lamina staining, while the Vimentin antibody reveals cytoplasmic intermediate filaments.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

NBP2-26504
In vivo assay: IKK gamma Inhibitor Peptide Set [NBP2-26504] - NBD peptide blocks constitutive NF-kB as shown by EMSA. U266 cells were treated with 100 uM of control or NBD peptide for different time periods. Nuclear extracts were isolated and checked for NF-kB-DNA binding activity.In vivo assay: IKK gamma Inhibitor Peptide Set [NBP2-26504] - NBD peptide blocks constitutive NF-kB activation in human multiple myeloma cells. U266 cells were treated with 100 uM of control (A & B) or NBD peptide (C & D) for 12 hr, cytospun, plated on glass slides, air dried for 1 hr at room temperature and fixed with cold acetone. Slides were blocked with 5% normal goat serum for 1 hr and then incubated with rabbit polyclonal anti-human p65 antibody (A & C) followed by Ig-Alexa 594 second step. In control peptide treated cells, p65 translocates to nucleus (A), whereas NBD peptide prevents translocation of p65 into the nucleus (C). B & D: Nuclear staining with DNA binding dye.


Species Human, Mouse, Rat

22 Publications
NBP1-51911
Western Blot: IRF6 Antibody [NBP1-51911] - HEK293 overexpressing IRF6 and probed with (mock transfection in first lane).Immunohistochemistry-Paraffin: IRF6 Antibody [NBP1-51911] - Staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

5 Publications
NB100-2076
Western Blot: Elastin Antibody (BA-4) [NB100-2076] - Analysis of tropoelastin using the mAb BA-4 elastin antibody (NB100-2076). A: Western blot of tropoelastin purified from bovine ligamentum nuchae tissue minces. B: Autoradiogram of a gradient SDS-polyacrylamide gel showing [3H] leucine-labeled tropoelasti.Immunohistochemistry-Paraffin: Elastin Antibody (BA-4) [NB100-2076] - Formalin fixed paraffin embedded human kidney stained with Elastin antibody.

Mouse Monoclonal
Species Human, Porcine, Canine
Applications WB, IHC, IHC-P

     2 Reviews

2 Publications
AF1894
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, HT-29 human colon adenocarcinoma cell line, Raji human Burkitt's lymphoma cell line, and NR-6 mouse fibroblast cell line. PVDF membrane was probed with 0.1 µg/mL Goat Anti-Human/Mouse/Rat SHP‑2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1894) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB

NB110-8146
Immunocytochemistry/Immunofluorescence: Fibrillin 1 Antibody (11C1.3) [NB110-8146] - Analysis of Fibrillin-1 (green) showing staining in the cytoplasm of SH-SY5Y cells (right) compared to a negative control without primary antibody (left).Immunocytochemistry/Immunofluorescence: Fibrillin 1 Antibody (11C1.3) [NB110-8146] - Analysis of Fibrillin-1 (green) showing staining in the cytoplasm of A431 cells (right) compared to a negative control without primary antibody (left).

Mouse Monoclonal
Species Human, Porcine, Bovine
Applications WB, ICC/IF, IHC

2 Publications
461-SH/CF
1 μg/lane of Recombinant Mouse Sonic Hedgehog/Shh, N-Terminus was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.Recombinant Mouse Sonic Hedgehog/Shh, N-Terminus (Catalog # 461-SH/CF) induces alkaline phosphatase production by the C3H10T1/2 mouse embryonic fibroblast cell line. The ED<SUB>50</SUB> for this effect is 0.6‑3 μg/mL.


Species Mouse

24 Publications
NBP1-33610
Western Blot: Loricrin Antibody [NBP1-33610] - Whole cell extract (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with Loricrin antibody [N1], N-term diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: Loricrin Antibody [NBP1-33610] - Immunofluorescence:  [NBP1-33610] - Analysis of methanol-fixed Hep3B, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     1 Review

1 Publication

Related Genes

Skin Abnormalities has been researched against:

Related PTMs

Skin Abnormalities has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Skin Abnormalities is also known as Abnormality, Skin, Congenital Cutaneous Anomaly, Congenital Skin Anomalies, Congenital Skin Disorder, Skin Abnormality.