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Severe Mental Retardation: Disease Bioinformatics

Research of Severe Mental Retardation has been linked to Epilepsy, Microcephaly, Congenital Abnormality, Cytogenetic Abnormality, Muscle Hypotonia. The study of Severe Mental Retardation has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Severe Mental Retardation include Pathogenesis, Methylation, Myelination, Excretion, Transport. These pathways complement our catalog of research reagents for the study of Severe Mental Retardation including antibodies and ELISA kits against STRABISMUS, SLC25A5, ATRX, DCX, DMD.

Severe Mental Retardation Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Severe Mental Retardation below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 836 products for the study of Severe Mental Retardation that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NB100-56326
Western Blot: MeCP2 Antibody [NB100-56326] - analysis of MeCP2 in HeLa cell lysate using this antibody.Immunocytochemistry/Immunofluorescence: MeCP2 Antibody [NB100-56326] - MeCP2 antibody was tested in A431 cells at a 1:200 dilution against Dylight 488 (Green). Alpha tubulin and nuclei were counterstained against Dylight 568 (Red) and DAPI (Blue), respectively.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
NBP1-52084
Western Blot: Phenylalanine Hydroxylase Antibody [NBP1-52084] - (0.1ug/ml) staining of Mouse (A) and Rat (B) Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: Phenylalanine Hydroxylase Antibody [NBP1-52084] - Staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC-P, PEP-ELISA

1 Publication
NBP1-83077
Western Blot: ATRX Antibody [NBP1-83077] - Analysis in A-549 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using anti-ATRX antibody. Remaining relative intensity is presented. Loading control: anti-GAPDH.Immunohistochemistry-Paraffin: ATRX Antibody [NBP1-83077] - Staining of human liver shows no positivity in hepatocytes as expected.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

17 Publications
NB500-240
Western Blot: E6AP/UBE3A Antibody [NB500-240] - UBE3A Antibody [NB500-240] -  Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg), and mouse NIH3T3 (M; 50 mcg) cells.   Antibodies: Affinity purified rabbit anti-E6AP antibody used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.  E6AP was also immunoprecipitated by rabbit anti-E6AP antibody, which recognizes an upstream epitope.    Detection: Chemiluminescence with exposure times of 3 minutes (A and B).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IP

8 Publications
NBP2-57308
Immunocytochemistry/Immunofluorescence: MCT8/SLC16A2 Antibody [NBP2-57308] - Staining of human cell line U-251 MG shows localization to plasma membrane. Antibody staining is shown in green.Immunohistochemistry-Paraffin: MCT8/SLC16A2 Antibody [NBP2-57308] - Staining in human liver and skeletal muscle tissues. Corresponding SLC16A2 RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

NBP1-89953
Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining of human tonsil shows no positivity as expected.Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining of human heart muscle shows strong membranous positivity in myocytes.

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

2 Publications
NBP1-84881
Western Blot: CDKL5 Antibody [NBP1-84881] - Staining of human testis shows moderate nuclear positivity in cells.Immunocytochemistry/Immunofluorescence: CDKL5 Antibody [NBP1-84881] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
NBP1-92025
Western Blot: Invadolysin Antibody [NBP1-92025] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).Immunocytochemistry/Immunofluorescence: Invadolysin Antibody [NBP1-92025] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol & focal adhesion sites. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

H00027130-P02
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human

MAB97201
    Western  blot shows lysates of human heart tissue, mouse heart tissue, rat heart  tissue, and human liver tissue (negative control). PVDF membrane was probed with  0.05 µg/mL of Mouse Anti-Human/Mouse/Rat Myoglobin Monoclonal Antibody  (Catalog # MAB97201) followed by HRP-conjugated Anti-Mouse IgG Secondary  Antibody (Catalog # <a class=    Myoglobin  was detected in immersion fixed paraffin-embedded sections of human heart  using Mouse Anti-Human/Mouse/Rat Myoglobin Monoclonal Antibody (Catalog #  MAB97201) at 1.7 µg/mL for 1 hour at room temperature  followed by incubation with the Anti-Mouse IgG VisUCyte™  HRP Polymer Antibody (Catalog #  <a class=

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ELISA

NBP2-01770
Western Blot: FMRP Antibody (1C6) [NBP2-01770] Analysis of extracts (35ug) from 9 different cell lines by using anti-FMRP monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).Immunocytochemistry/Immunofluorescence: FMRP Antibody (1C6) [NBP2-01770] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY FMRP.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     1 Review

NBP1-82991
Western Blot: ZEB2 Antibody [NBP1-82991] - Analysis in human cell lines SK-MEL-30 and Caco-2 using Anti-ZEB2 antibody. Corresponding ZEB2 RNA-seq data are presented for the same cell lines. Loading control: Anti-HDAC1.Immunohistochemistry-Paraffin: ZEB2 Antibody [NBP1-82991] - Staining in human cerebral cortex and pancreas tissues. Corresponding ZEB2 RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

     1 Review

8 Publications
NBP2-34260
Immunohistochemistry-Paraffin: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Formalin-fixed, paraffin-embedded human pancreas stained with insulin Monoclonal Antibody (E2-E3)SDS-Page: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260]

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, Flow, ICC/IF

     4 Reviews

NBP1-19083
Western Blot: TCF7L2 Antibody [NBP1-19083] - Jurkat cell line.Immunocytochemistry/Immunofluorescence: TCF7L2 Antibody [NBP1-19083] - TCF7L2 antibody was tested in Hela cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

1 Publication
NBP1-87769
Western Blot: LIS1 Antibody [NBP1-87769] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: LIS1 Antibody [NBP1-87769] - Immunofluorescent staining of human cell line U-251 MG shows localization to centrosome.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     2 Reviews

NBP1-92684
Western Blot: Doublecortin Antibody (3E1) [NBP1-92684] - Analysis of rat whole brain lysates using mouse mAb to Doublecortin (DCX), NBP1-92684, dilution 1:1,000 in green: [1] protein standard (red), [2] adult rat brain, [3] embryonic E20 rat brain. Strong bands at 40, 45kDa correspond to DCX protein, detected only in the developing brain.Immunocytochemistry/Immunofluorescence: Doublecortin Antibody (3E1) [NBP1-92684] - Analysis of cortical neuron-glial cell culture from E20 rat stained with mouse mAb to Doublecortin (DCX), NBP1-92684, dilution 1:1,000 in red, and costained with chicken pAb to Microtubule Associated Protein2 (MAP2), dilution 1:10,000 in green. The blue is DAPI staining of nuclear DNA. DCX antibody reveals strong cytoplasmic staining in a population of small developing neurons and their processes, while MAP2 antibody stains dendrites and perikarya of mature neurons. Therefore DCX antibody is an excellent marker of developing neuronal cells.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP1-56594
Western Blot: FOXG1A/FOXG1B Antibody [NBP1-56594] - Jurkat cell lysate, Antibody Titration: 5.0-8.0ug/mlImmunohistochemistry-Paraffin: FOXG1A/FOXG1B Antibody [NBP1-56594] - Human Liver Tissue, antibody concentration 4-8ug/ml. Cells with positive label: Hepatocytes (indicated with arrows) 400X magnification.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-56762
Western Blot: Adenine Nucleotide Translocator 2 Antibody [NBP2-56762] - Western blot analysis in human cell line RT-4 and human cell line U-251 MG.Immunocytochemistry/Immunofluorescence: Adenine Nucleotide Translocator 2 Antibody [NBP2-56762] - Staining of human cell line PC-3 shows localization to mitochondria.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

AF1518
Western blot shows lysates of HEK293 human embryonic kidney cell line, PC‑12 rat adrenal pheochromocytoma cell line, and NIH‑3T3 mouse embryonic fibroblast cell line. PVDF membrane was probed with 0.1 µg/mL of Rabbit Anti-Human/Mouse/Rat RSK2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1518) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # <A class=NoLineLink href=RSK2 was detected in immersion fixed frozen sections of mouse embryo using Rabbit Anti-Human/Mouse/Rat RSK2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1518) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rabbit HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC


Related Genes

Severe Mental Retardation has been researched against:

Related PTMs

Severe Mental Retardation has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Severe Mental Retardation is also known as Severe Intellectual Disabilities, Severe Mental Handicap, Severe Mental Subnormality.