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Schizophrenia: Disease Bioinformatics

Schizophrenia is a mental disorder which affects the person’s ability to tell what is real and not real, to act normal, and to think clearly. The cause of Schizophrenia is still unclear, but some think it is triggered by a tragic event or family history of the disorder. Schizophrenia usually progress slowly during the teen years and has symptoms including isolation, hallucinations, delusions, and trouble sleeping or concentrating. Schizophrenia is treated with antipsychotic medications which most people stay on for life. During the time of a Schizophrenic episode, people are usually put into hospitals for safety reasons.

Schizophrenia Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Schizophrenia below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1562 products for the study of Schizophrenia that can be applied to Chromatin Immunoprecipitation, Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-85818
Western Blot: COMT Antibody [NBP1-85818] - Analysis in human cell lines MCF-7 and PC-3 using Anti-COMT antibody. Corresponding COMT RNA-seq data are presented for the same cell lines. Loading control: Anti-COX4I1.Immunohistochemistry-Paraffin: COMT Antibody [NBP1-85818] - Staining in human placenta and pancreas tissues using anti-COMT antibody. Corresponding COMT RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

1 Publication
AF682
Prolactin was detected in immersion fixed paraffin-embedded sections of human testis using Goat Anti-Human Prolactin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF682) at 1 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=    Western  blot shows lysates of human pituitary tissue. PVDF membrane was probed with  0.25 µg/mL of Goat Anti-Human Prolactin Antigen Affinity-purified  Polyclonal Antibody (Catalog # AF682) followed by HRP-conjugated Anti-Goat  IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, IHC, ELISA(Cap)

3 Publications
248-BD
1 μg/lane of Recombinant Human BDNF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.Recombinant Human BDNF (Catalog #<br>248‑BD) stimulates cell proliferation in the BaF mouse pro-B cell line transfected with TrkB. The ED<sub>50</sub> for this effect is 0.2-2 ng/mL.


Species Human, Mouse, Rat

     6 Reviews

89 Publications
215-GM/CF
1 μg/lane of Recombinant Human GM-CSF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.Recombinant Human GM-CSF (Catalog # 215-IL/CF) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human

197 Publications
NBP2-42388
Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.

Mouse Monoclonal
Species Human
Applications WB, IHC, IHC-P

MAB9266
    Dopamine  D2 R/DRD2 was detected in immersion fixed paraffin-embedded sections of human  brain (striatum) using Mouse Anti-Human Dopamine D2 R/DRD2 Monoclonal  Antibody (Catalog # MAB9266) at 5 µg/mL for 1 hour at room  temperature followed by incubation with the Anti-Mouse IgG  VisUCyte™  HRP Polymer  Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human
Applications IHC

NBP1-00178
Immunohistochemistry-Paraffin: DIO2 Antibody [NBP1-00178] - Staining of paraffin embedded Human Small Intestine.Immunohistochemistry-Frozen: DIO2 Antibody [NBP1-00178] - IHC analysis of DIO2 in cryo-sectioned Mouse Hippocampus using NBP1-00178 at 2ug/ml. Microwaved antigen retrieval with citrate buffer pH 4.5, HRP-staining.

Goat Polyclonal
Species Mouse
Applications WB, IHC, IHC-Fr

4 Publications
NBP2-34260
Immunohistochemistry-Paraffin: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Formalin-fixed, paraffin-embedded human pancreas stained with insulin Monoclonal Antibody (E2-E3)SDS-Page: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260]

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, Flow, ICC/IF

     4 Reviews

396-HB
Recombinant Human NRG1-beta 1/HRG1-beta 1 EGF Domain (Catalog # 396-HB) stimulates cell proliferation of the MCF-7 human breast cancer cell line. The ED<SUB>50</SUB> for this effect is 0.06-0.3 ng/mL.1 μg/lane of Recombinant Human NRG1-beta 1/HRG1-beta 1 EGF Domain was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 8 kDa.


Species Human

34 Publications
NBP2-20823
Western Blot: USH1G Antibody [NBP2-20823] - Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE gel, diluted at 1:1000.Immunohistochemistry-Paraffin: USH1G Antibody [NBP2-20823] - Immunohistochemical analysis of paraffin-embedded gastric ca, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-85299
Western Blot: Dysbindin Antibody [NBP1-85299] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: Dysbindin Antibody [NBP1-85299] - Immunofluorescent staining of human cell line A-431 shows localization to microtubules.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB110-40773
Immunocytochemistry/Immunofluorescence: DISC1 Antibody [NB110-40773] - DISC1 antibody was tested in PC-12 cells at 1:100 with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 549 (red).Immunohistochemistry: DISC1 Antibody [NB110-40773] - Staining of DISC1 in human brain neurons and neuropil at 2.5ug/ml. 40X.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications ICC/IF, IHC, IHC-Fr

1 Publication
NBP1-02398
Immunohistochemistry-Paraffin: Dopamine D3 R/D3DR Antibody [NBP1-02398] - Staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.

Rabbit Polyclonal
Species Human, Monkey
Applications ELISA, IHC, IHC-P

NB100-616
Western Blot: KAT3B/p300 Antibody (RW105) [NB100-616] - p300 detected in a HeLa nuclear extract using NB 100-616 (1:250).  ECL: 20 minute exposure.Immunocytochemistry/Immunofluorescence: KAT3B/p300 Antibody (RW105) [NB100-616] - HeLa cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X PBS + 0.5% Triton-X100.  The cells were incubated with anti-KAT3B/p300 (RW105) at 5 ug/ml overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution.  Nuclei were counterstained with DAPI (Blue).  Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ChIP, EM

8 Publications
AF2086
    Western  blot shows lysates of human brain (hypothalamus) tissue, mouse brain (total)  tissue, and rat brain (total) tissue. PVDF membrane was probed with  1 µg/mL of Goat Anti-Human/Mouse/Rat GAD1/GAD67 Antigen Affinity-purified  Polyclonal Antibody (Catalog # AF2086) followed by HRP-conjugated Anti-Goat  IgG Secondary Antibody (Catalog # <a class=    Simple  Western lane view shows lysates of mouse brain tissue, loaded at  0.2 mg/mL. A specific band was detected for GAD1/GAD67 at  approximately 65 kDa (as indicated) using 1 µg/mL of Goat  Anti-Human/Mouse/Rat GAD1/GAD67 Antigen Affinity-purified Polyclonal Antibody  (Catalog # AF2086) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG  Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

2 Publications
NBP2-29323
Functional (Inhibition): NFkB p105/p50 Inhibitor Peptide Set [NBP2-29323] - TLR5/NF-kB/SEAPorter HEK 293 (NBP2-26277) cells were plated in 96-well plates at 5 x 10^4 cells/well for 16 h. Cells were preincubated with different concentrations (0, 1, 5, 10, 25 and 50 uM) of Inhibitory Peptide (NBP2-29323) and Control Peptide (NBP2-29334) for 1 h. Cells were then stimulated with 1 ng/ml Flagellin (NBP2-25289) for 24 h. Secreted alkaline phosphatase (SEAP) was analyzed using SEAPorter Assay Kit (NBP2-25285). *p < 0.05 versus control peptide at the corresponding concentrations (Mann-Whitney U test).


Species Human, Mouse, Rat

10 Publications
NB100-1533
Western Blot: POMC Antibody [NB100-1533] - Western blot analysis of POMC using NB100-1533 at 0.01ug/ml in NIH 3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: POMC Antibody [NB100-1533] - Analysis in human Anterior Pituitary Gland shows vesilulate staining in glandular cells.

Goat Polyclonal
Species Human, Mouse, Porcine
Applications WB, ICC/IF, IHC

7 Publications
273-F9/CF


Species Human

20 Publications
NBP1-88650
Western Blot: ARHGEF7 Antibody [NBP1-88650] - Analysis in human cell line SH-SY5Y.Immunohistochemistry-Paraffin: ARHGEF7 Antibody [NBP1-88650] - Staining of human duodenum shows cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

DDX0131P-100
Immunocytochemistry/Immunofluorescence: CD40/TNFRSF5 Antibody (mAb89) [DDX0131P-100] - CD40-transfected L cells stained.Immunohistochemistry: CD40/TNFRSF5 Antibody (mAb89) [DDX0131P-100] - IHC staining on Bouin paraffinlymph node section. HumanCD40 stained with mAb 89.

Mouse Monoclonal
Species Human
Applications Flow, Func, ICC/IF

11 Publications