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Polydactyly: Disease Bioinformatics

Research of Polydactyly has been linked to Congenital Abnormality, Syndactyly, Radial Polydactyly, Dysplasia, Congenital Hand Deformities. The study of Polydactyly has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Polydactyly include Limb Development, Pathogenesis, Ossification, Localization, Cell Death. These pathways complement our catalog of research reagents for the study of Polydactyly including antibodies and ELISA kits against RETINAL DYSTROPHY, PDN, CHONDRODYSPLASIA, BBS1, BBS2.

Polydactyly Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Polydactyly below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 424 products for the study of Polydactyly that can be applied to Western Blot, Flow Cytometry, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.

8908-SH/CF
Recombinant Human Shh proteins induce  alkaline phosphatase production by mesenchymal stem cells. High Activity Shh (green), purified from HEK293 cells and containing the correct post-translational modifications (cholesterol and fatty acids), is over 14-fold more active than E. coli-purified Recombinant Human Shh-N (C24II)<br>N-Terminus (Catalog # <a class=LC/ESI-MS analysis of Recombinant Human (rh)SHH, HighActivity shows  major peaks at 20119.3,20145.2, and 20171.6 Da,  suggesting thatrecombinant human SHH molecules are dual-modified with cholesterol atC-terminus, and fatty acids (lauric acid, myristic acid, and palmitic acid) atthe<br>N-terminus. The minor peaks at 19776 Da corresponds to rhSHH with onlyfatty acid modification.


Species Human

AF3690
Western blot shows lysates of mouse embryo tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse GLI‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3690) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=GLI‑3 was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line using Human/Mouse GLI‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3690) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (yellow; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human, Mouse
Applications WB, ChIP, ICC

     4 Reviews

21 Publications
NBP1-92123
Western Blot: MKKS Antibody [NBP1-92123] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: MKKS Antibody [NBP1-92123] - Immunofluorescent staining of human cell line U-2 OS shows localization to centrosome.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-91695
Immunohistochemistry: BBS2 Antibody [NBP1-91695] - Staining of human fallopian tube shows strong membranous and cytoplasmic positivity in ciliated cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-52149
Immunohistochemistry-Paraffin: HOXD13 Antibody [NBP1-52149] - Staining of Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications IHC, IHC-P, PEP-ELISA

1 Publication
423-F8/CF
1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.Recombinant Human/Mouse FGF-8b (Catalog # 423-F8/CF) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED<sub>50</sub> for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin.


Species Human, Mouse

33 Publications
NBP2-34106
Immunohistochemistry-Paraffin: BBS1 Antibody [NBP2-34106] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

7460-F4/CF


Species Human

NBP1-84038
Immunocytochemistry/Immunofluorescence: Ellis van Creveld syndrome Antibody [NBP1-84038] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.Immunohistochemistry-Paraffin: Ellis van Creveld syndrome Antibody [NBP1-84038] - Staining of human duodenum shows moderate cytoplasmic and nuclear positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP1-88691
Western Blot: MKS1 Antibody [NBP1-88691] - Analysis in human cell line HEK 293.Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88691] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NB600-600
Immunohistochemistry-Paraffin: GLI-1 Antibody [NB600-600] - IHC-P analysis of a formalin fixed paraffin embedded mouse brain section using GLI-1 antibody at 1:600 dilution.   Flow (Intracellular): GLI-1 Antibody [NB600-600] - intracellular staining for GLI-1 in untreated human B cell lines (BCWM.1, MWCL-1 and RPCI-WM1)  using anti-GLI-1 antibody. Rabbit IgG Isotype Control (Cat# NBP2-36463) was used as a negative control. Image courtesy of Sherine Elsawa, Northern Illinois University.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ChIP, ELISA

22 Publications
NBP1-06590
Western Blot: Meckelin Antibody [NBP1-06590] - Immunodetection of Meckelin (120kDa) in whole cell extracts of HEK293 cells.Immunohistochemistry-Paraffin: Meckelin Antibody [NBP1-06590] - Staining of kidney tissue section with Meckelin Antibody (NBP1-06590).

Rabbit Polyclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

1 Publication
NBP1-89276
Immunocytochemistry/Immunofluorescence: LMBR1 Antibody [NBP1-89276] - Staining of human cell line A-431 shows positivity in cytoplasm.Immunohistochemistry-Paraffin: LMBR1 Antibody [NBP1-89276] - Staining of human duodenum shows strong positivity in smooth muscle cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP1-86248
Western Blot: BBS4 Antibody [NBP1-86248] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: BBS4 Antibody [NBP1-86248] - Staining of human cell line U-2 OS shows positivity in cytoplasm.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

314-BP/CF
1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.<p style=Recombinant Human BMP-4 (Catalog #<BR>314-BP/CF) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED<SUB>50</SUB> for this effect is 2.5-15 ng/mL.


Species Human

237 Publications
NB200-118
Western Blot: Patched 1 Antibody [NB200-118]-Analysis of Human PTCH1 in Fetal brain Lysate with anti huPTCH1 at a 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

3 Publications
NBP1-86103
Western Blot: ZP2 Antibody [NBP1-86103] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunohistochemistry-Paraffin: ZP2 Antibody [NBP1-86103] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P


Related Genes

Polydactyly has been researched against:

Related PTMs

Polydactyly has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Polydactyly is also known as polydactyly, polydactyly, postaxial, postaxial polydactyly, polydactyly postaxial, supernumerary digits, polydactylism, hyperdactyly, extra digits, polydactylia.