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Polydactyly: Disease Bioinformatics

Research of Polydactyly has been linked to Congenital Abnormality, Syndactyly, Radial Polydactyly, Dysplasia, Congenital Hand Deformities. The study of Polydactyly has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Polydactyly include Limb Development, Pathogenesis, Ossification, Localization, Cell Death. These pathways complement our catalog of research reagents for the study of Polydactyly including antibodies and ELISA kits against SHH, GLI3, MKKS, BBS2, RETINAL DYSTROPHY.

Polydactyly Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Polydactyly below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 571 products for the study of Polydactyly that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.

1845-SH
1 μg/lane of Recombinant Human Sonic Hedgehog/Shh (C24II), N-Terminus was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 22 kDa.MALDI-TOF analysis of Recombinant Human Sonic Hedgehog/Shh (C24II), N-Terminus. The major peak corresponds to the calculated molecular mass, 19814 Da. The minor peak at 20029  is a matrix-associated artifact of the MALDI-TOF.


Species Human

     5 Reviews

35 Publications
AF3690
Western blot shows lysates of mouse embryo tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse GLI‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3690) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Jurkat human acute T cell leukemia cell line treated with 50 ng/mL PMA and 200 ng/mL calcium ionomycin for 30 minutes was fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. GLI‑3/DNA complexes were immunoprecipitated using 5 μg Goat Anti-Human/Mouse GLI‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3690) or control antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human, Mouse
Applications WB, ChIP, ICC

     5 Reviews

33 Publications
NBP1-92123
Western Blot: MKKS Antibody [NBP1-92123] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: MKKS Antibody [NBP1-92123] - Immunofluorescent staining of human cell line U-2 OS shows localization to centrosome.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

H00000583-P01
SDS-Page: Recombinant Human BBS2 Protein [H00000583-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human

NBP1-52149
Immunocytochemistry/Immunofluorescence: HOXD13 Antibody [NBP1-52149] - Immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).Immunohistochemistry-Paraffin: HOXD13 Antibody [NBP1-52149] - Staining of Human Prostate. Antibody at 3.8 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
423-F8
1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.Recombinant Human/Mouse FGF-8b (Catalog # 423-F8) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED<sub>50</sub> for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin.


Species Human, Mouse

     3 Reviews

44 Publications
H00000582-P01
SDS-Page: Recombinant Human BBS1 Protein [H00000582-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human

1 Publication
7460-F4/CF


Species Human

2 Publications
NBP1-84038
Immunocytochemistry/Immunofluorescence: Ellis van Creveld syndrome Antibody [NBP1-84038] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.Immunohistochemistry-Paraffin: Ellis van Creveld syndrome Antibody [NBP1-84038] - Staining of human liver shows very weak positivity in hepatocytes as expected.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP1-88691
Western Blot: MKS1 Antibody [NBP1-88691] - Analysis in human cell line HEK 293.Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88691] - Staining of human kidney.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NB600-600
Immunohistochemistry-Paraffin: GLI-1 Antibody [NB600-600] - Staining in canine hair follicle.  Image from a verified customer review.Flow (Intracellular): GLI-1 Antibody [NB600-600] - Staining for GLI-1 in untreated human B cell lines (BCWM.1, MWCL-1 and RPCI-WM1)  using anti-GLI-1 antibody. Rabbit IgG Isotype Control (Cat# NBP2-36463) was used as a negative control. Image courtesy of Sherine Elsawa, Northern Illinois University.

Rabbit Polyclonal
Species Human, Mouse, Canine
Applications WB, ChIP, ELISA

     1 Review

31 Publications
NBP1-06590
Western Blot: Meckelin Antibody [NBP1-06590] - Immunodetection of Meckelin (120kDa) in whole cell extracts of HEK293 cells.Immunohistochemistry-Paraffin: Meckelin Antibody [NBP1-06590] - Staining of kidney tissue section with Meckelin Antibody (NBP1-06590).

Rabbit Polyclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

1 Publication
NBP1-89276
Immunocytochemistry/Immunofluorescence: LMBR1 Antibody [NBP1-89276] - Staining of human cell line A-431 shows positivity in cytoplasm.Immunohistochemistry-Paraffin: LMBR1 Antibody [NBP1-89276] - Staining of human duodenum shows strong positivity in smooth muscle cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP1-86248
Western Blot: BBS4 Antibody [NBP1-86248] - Analysis in control (vector only transfected HEK293T lysate) and BBS4 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: BBS4 Antibody [NBP1-86248] - Staining of human duodenum shows strong cytoplasmic and membranous positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

314-BP
1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.<p style=Recombinant Human BMP-4 (Catalog #<BR>314-BP/CF) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED<SUB>50</SUB> for this effect is 2.5-15 ng/mL.


Species Human

     6 Reviews

351 Publications
NBP1-71662
Western Blot: Patched 1/PTCH Antibody [NBP1-71662] -  Analysis of Patched 1 in human skeletal muscle protein.Immunohistochemistry-Paraffin: Patched 1/PTCH Antibody [NBP1-71662] - IHC analysis of formalin fixed paraffin embedded tissue section of mouse lung using 1:50 dilution of PTCH antibody with HRP-DAB detection and hematoxylin counterstaining. The antibody generated a specific membrane-cytoplasmic staining in bronchiolar and alveolar epithelial cells with stronger signal towards the membranes of the cells.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

3 Publications
NBP2-93167
Western Blot: ZP2 Antibody [NBP2-93167] - Analysis of extracts of various cell lines, using ZP2 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.Immunocytochemistry/Immunofluorescence: ZP2 Antibody [NBP2-93167] - Analysis of rat oophoroma cells using ZP2 at dilution of 1:100. Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF


Related Genes

Polydactyly has been researched against:

Related PTMs

Polydactyly has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Polydactyly is also known as polydactyly, polydactyly, postaxial, postaxial polydactyly, polydactyly postaxial, supernumerary digits, polydactylism, hyperdactyly, extra digits, polydactylia.