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Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy: Disease Bioinformatics

Research of Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy has been linked to Dementia, Leukoencephalopathies, Lipodystrophy, Bone Cysts, Presenile Dementia. The study of Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy include Pathogenesis, Osteoclast Differentiation, Bone Resorption, Cell Activation, Inflammatory Response. These pathways complement our catalog of research reagents for the study of Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy including antibodies and ELISA kits against TYROBP, TREM2, TREM1, BGLAP, HCST.

Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 1859 products for the study of Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NBP3-15669
Western Blot: SHP-1 Antibody (7I1K3) [NBP3-15669] - Western blot analysis of extracts of Raji cells, using SHP-1 antibody (NBP3-15669) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.Immunohistochemistry: SHP-1 Antibody (7I1K3) [NBP3-15669] - Immunofluorescence analysis of mouse spleen using SHP-1 Rabbit mAb (NBP3-15669) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

H00001513-M01
Western Blot: Cathepsin K Antibody (2F1) [H00001513-M01] - Analysis of CTSK expression in transfected 293T cell line by CTSK monoclonal antibody (M01), clone 2F1.Lane 1: CTSK transfected lysate(37 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: Cathepsin K Antibody (2F1) [H00001513-M01] - HeLa cell.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

1 Publication
NBP1-32945
Western Blot: SYK Antibody [NBP1-32945] - SYK antibody detects SYK protein by western blot analysis. Whole cell extracts (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with SYK antibody at a dilution of 1:2000. HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: SYK Antibody [NBP1-32945] - Analysis of methanol-fixed A431, using antibody at 1:200 dilution.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP1-43363
Immunohistochemistry-Paraffin: M-CSFR/CD115 Antibody (AFS98) [NBP1-43363] - Mouse tumor tissue stained with M-CSFR/CD115 Antibody (AFS98). Tissue sections were deparaffinized and incubated with the antibody O/N at 4C. IHC-P image submitted by a verified customer review.Flow Cytometry: M-CSF R/CD115 Antibody (AFS98) [NBP1-43363] - Analysis using the Biotin conjugate of NBP1-43363. Staining of thioglycolate-induced peritoneal exudate cells with Anti-Mouse CD115 (c-fms) PE. Appropriate isotype controls were used (open histogram).

Rat Monoclonal
Species Mouse
Applications WB, Flow, IHC

     2 Reviews

2 Publications
NBP1-77397
Immunocytochemistry/Immunofluorescence: HSP60 Antibody [NBP1-77397] - HeLa cells were fixed in 4% paraformaldehyde for 10 minutes and permeabilized in 0.05% Triton X-100 in PBS for 5 minutes. The cells were incubated with HSP60 Antibody (NBP1-77397) at 1 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:1000 dilution for 60 minutes. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 100X objective and digitally deconvolved.Western Blot: HSP60 Antibody [NBP1-77397] - Analysis of extracts from HeLa and COS cells using NBP1-77397 Hsp60 antibody at 1:1000

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, Flow

     4 Reviews

6 Publications
NBP1-85313
Immunohistochemistry-Paraffin: DAP12 Antibody [NBP1-85313] - Analysis in human bone marrow and skeletal muscle tissues using NBP1-85313 antibody. Corresponding TYROBP RNA-seq data are presented for the same tissues.Western Blot: DAP12 Antibody [NBP1-85313] - Analysis in control (vector only transfected HEK293T lysate) and TYROBP over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NBP2-22203
Western Blot: ERK1 Antibody (1E5) [NBP2-22203] - Western blot analysis of whole cell lysates from (1) MCF7 (2) NIH3T3 cell lines using ERK1 antibody (clone 1E5) at 1:1000 dilution. The signal was developed using HRP labeled goat-anti Mouse secondary antibody with ECL based detection. Immunocytochemistry/Immunofluorescence: ERK1 Antibody (1E5) [NBP2-22203] - Analysis of NIH/3T3 cells using ERK1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, Flow

NBP2-24716
Western Blot: MTSS1 Antibody [NBP2-24716] - Analysis of MTSS1 in human testis lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse and 4) rat testis lysate using NBP2-24716 at 2 ug/ml, 4 ug/ml and 2 ug/ml, respectively.Immunohistochemistry-Paraffin: MTSS1 Antibody [NBP2-24716] - Analysis of human colon using this antibody at 10 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Primate
Applications WB, ICC/IF, IHC

1 Publication
AF1729
    TREM2  was detected in immersion fixed RAW 264.7 mouse monocyte/macrophage  cell line using Sheep Anti-Mouse TREM2 Antigen Affinity-purified Polyclonal  Antibody (Catalog # AF1729) at 1.7 µg/mL for 3 hours at  room temperature. Cells were stained using the NorthernLights™  557-conjugated Anti-Sheep IgG Secondary Antibody (red; Catalog #  <a class=              Recombinant  Mouse TREM2 protein was serially diluted 2-fold and captured by Sheep  Anti-Mouse TREM2 Antigen Affinity-purified Polyclonal Antibody (Catalog #  AF1729) coated on a Clear Polystyrene Microplate (Catalog # <a class=

Sheep Polyclonal
Species Mouse
Applications WB, ELISA, ICC

     1 Review

26 Publications
AF2685
Western blot shows lysates of MDA‑MB‑468 human breast cancer cell line and HepG2 human hepatocellular carcinoma cell line untreated (-) or treated (+) with 50 μM pervanadate (PV) for 10 minutes. PVDF membrane was probed with 1 µg/mL of Rabbit Anti-Human Phospho-Src (Y419) Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2685), followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Src phosphorylated at Y419 was detected in immersion fixed paraffin-embedded sections of human colon using Rabbit Anti-Human Phospho-Src (Y419) Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2685) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rabbit HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, IHC

     1 Review

6 Publications
AF3129
APLP‑1 was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Goat Anti-Human APLP‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3129) at 0.3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (<a class=NoLineLink href=Simple Western lane view shows lysates of human brain (hippocampus) and mouse brain (hippocampus), loaded at 0.2 mg/mL. A specific band was detected for APLP‑1 at approximately 119 kDa (as indicated) using 25 µg/mL of Goat Anti-Human APLP‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3129) . This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Goat Polyclonal
Species Human
Applications WB, Simple Western, IHC

1 Publication
MAB1419
Osteocalcin was detected in immersion fixed MG‑63 human osteosarcoma cell line using Mouse Anti-Human/Rat Osteocalcin Monoclonal Antibody (Catalog # MAB1419) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=Osteocalcin was detected in human mesenchymal stem cells differentiated into osteocytes using Mouse Anti-Human/Rat Osteocalcin Monoclonal Antibody (Catalog # MAB1419) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=

Mouse Monoclonal
Species Human, Rat
Applications IHC, CyTOF-ready, ICC

     3 Reviews

33 Publications
462-TR/CF
<P align=left>Recombinant Mouse TRANCE/TNFSF11/RANK L (Catalog # 462-TR/CF) induces osteoclast differentiation of the RAW 264.7 mouse monocyte/macrophage cell line. The ED<SUB>50</SUB> for this effect is 5-15 ng/mL in the presence of 2.5 μg/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # <A class=NoLineLink href=1 μg/lane of Recombinant Mouse TRANCE/TNFSF11/RANK L was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 36 kDa.


Species Mouse
Applications BA

84 Publications
DY805
 Osteoprotegerin/TNFRSF11B [Biotin]


Species Human
Applications ELISA

82 Publications
DTRM10C
N/A TREM1 [HRP] TREM1 [HRP]


Species Human
Applications ELISA

14 Publications
NB100-56508
Western Blot: RANK/TNFRSF11A Antibody (9A725) [NB100-56508] - Analysis of RANK in transfected 293 cells using RANK antibody at 2 ug/ml.Flow Cytometry: RANK/TNFRSF11A Antibody (9A725) - BSA Free [NB100-56508] - An intracellular stain was performed on Raw264.7 cells with RANK/TNFRSF11A Antibody (9A725) NB100-56508 (blue) and a matched isotype control MAB002 (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature, followed by Mouse IgG (H+L) Cross-Adsorbed Secondary Antibody, Dylight 550 (84540, Thermo Fisher).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, IHC

18 Publications
NB300-817
Immunocytochemistry/Immunofluorescence: VAV3 Antibody [NB300-817] - Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).Immunohistochemistry-Paraffin: VAV3 Antibody [NB300-817] - Staining of paraffin embedded Human Spleen. Antibody at 7.5 ug/mL. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.

Goat Polyclonal
Species Human
Applications Flow, ICC/IF, IHC

1 Publication
MAB97861
Immunohistochemistry-Paraffin: DAP10/HCST Antibody (982101) [Unconjugated] [MAB97861] - DAP10/HCST was detected in immersion fixed paraffin-embedded sections of human kidney using Mouse Anti-Human DAP10/HCST Monoclonal Antibody (Catalog # MAB97861) at 5 ug/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte HRP Polymer Antibody (Catalog # VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell nuclei.

Mouse Monoclonal
Species Human
Applications Flow, IHC, IHC-P

NB100-1028
Western Blot: AIF-1/Iba1 Antibody [NB100-1028] - GM1 effects on brain microglia in vivo, after peripheral administration of LPS. I mmunoblot in whole brain lysates and densitometric analysis show LPS-dependent increase in AIF-1/Iba1 expression. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/34991625/) licensed under a CC-BY licence.Immunohistochemistry: AIF-1/Iba1 Antibody [NB100-1028] - Reactive microglia (green) in peritumoral area of IC injected human glioblastoma cells in mouse brain. NeuN (red), DAPI (blue). Antibody at 1:250. IHC image submitted by a verified customer review.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     21 Reviews

289 Publications

Related Genes

Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy has been researched against:

Related PTMs

Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy is also known as Nasu-hakola Disease, Plosl, Presenile Dementia With Bone Cysts.