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Pelger-huet Anomaly: Disease Bioinformatics

Research of Pelger-huet Anomaly has been linked to Leukemia, Dysplasia, Anemia, Dysmyelopoietic Syndromes, Leukemia, Myelocytic, Acute. The study of Pelger-huet Anomaly has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Pelger-huet Anomaly include Segmentation, Pathogenesis, Chemotaxis, Phagocytosis, Hypersensitivity. These pathways complement our catalog of research reagents for the study of Pelger-huet Anomaly including antibodies and ELISA kits against LAMIN A, CASPASE 6, CHONDRODYSPLASIA, INTERMEDIATE FILAMENT, AMPD1.

Pelger-huet Anomaly Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Pelger-huet Anomaly below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 505 products for the study of Pelger-huet Anomaly that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

H00003930-B01P
Western Blot: Lamin B Receptor Antibody [H00003930-B01P] - Analysis of LBR expression in transfected 293T cell line by LBR polyclonal antibody.  Lane 1: LBR transfected lysate(67.65 KDa). Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: Lamin B Receptor Antibody [H00003930-B01P] - Analysis of purified antibody to LBR on HeLa cell. (antibody concentration 10 ug/ml)

Mouse Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC-P

     1 Review

NBP2-25151
Western Blot: Lamin A + C Antibody (4C4) [NBP2-25151] - Stripe blots of crude HeLa cell extract. Note two strong clean bands at 74 kDa and 64 kDa, corresponding to Lamin A and C, in lane 6. Lane 5 was stained with an antibody to Enolase 1. Lanes 3 and 4 were stained with NBP2-25142, the monoclonal antibody to all six Actin isotypes. Molecular weights of each protein are as indicated.Immunocytochemistry/Immunofluorescence: Lamin A + C Antibody (4C4) [NBP2-25151] - HeLa cells staing with NBP2-25151 (red), and counterstained with chicken polyclonal antibody to Vimentin NB300-223 (green) and DNA (blue). NBP2-25151 reveals strong nuclear lamina staining, while the Vimentin antibody reveals cytoplasmic intermediate filaments.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

NBP1-89827
Western Blot: 14-3-3 epsilon Antibody [NBP1-89827] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.Immunocytochemistry/Immunofluorescence: 14-3-3 epsilon Antibody [NBP1-89827] - Staining of human cell line A-431 shows positivity in cytoplasm.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

2 Publications
NB100-55256
Western Blot: SAP155 Antibody [NB100-55256] - Detection of Human SF3b155/SAP155 on HeLa whole cell lysate (5, 15, and 50 microgram) and 293T cell lysate (50 microgram) using Nb100-55256. SF3b155/SAP155 was also immunoprecipitated by  rabbit anti-SF3b155/SAP155 antibody NB100-55255.Immunohistochemistry: SAP155 Antibody [NB100-55256] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti- SF3b155/SAP155 used at a dilution of 1:200 (1ug/ml). Detection: DAB

Rabbit Polyclonal
Species Human
Applications WB, IHC-P, IP

NBP1-87769
Western Blot: LIS1 Antibody [NBP1-87769] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: LIS1 Antibody [NBP1-87769] - Immunofluorescent staining of human cell line U-251 MG shows localization to centrosome.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     2 Reviews

H00171023-M05
Western Blot: ASXL1 Antibody (6E2) [H00171023-M05] - Analysis of ASXL1 expression in MCF-7 (Cat # L046V1).ELISA: ASXL1 Antibody (6E2) [H00171023-M05] - Detection limit for recombinant GST tagged ASXL1 is 0.3 ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA

3 Publications
NB100-56403
Western Blot: Lamin B1 Antibody [NB100-56403] - analysis of Lamin B1 in 30 ugs of A) HeLa and B) Hep-2 whole cell lysate using this antibody. 5 ug/ml.

Rabbit Polyclonal
Species Human
Applications WB

4 Publications
NBP2-43834
Western Blot: Lamin B2 Antibody (144) [NBP2-43834] - Non-transfected (-) and transfected (+) HepG2 whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Lamin B2 antibody [144]. The HRP-conjugated anti-mouse IgG antibody (NBP2-19382) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: Lamin B2 Antibody (144) [NBP2-43834] - Analysis of HeLa cells were fixed in 2% paraformaldehyde for 30 min. Red: LMNB2 protein stained by Lamin B2 antibody [144] diluted at 1:1000. Green: alpha Tubulin antibody diluted at 1:1000. Blue: Hoechst 33342 staining. [Images captured by Olympus FV1000 Confocal Laser Scanning Microscope]

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

NB100-56114
Western Blot: Caspase-6 Antibody [NB100-56114] - Analysis of Caspase-6 using Caspase-6 polyclonal antibody. Recombinant catalytically active caspase-6 was western blotted with Active/Cleaved Caspase-6 antibody. The antibody detected both the large and small subunits of Caspase-6.Immunohistochemistry-Paraffin: Caspase-6 Antibody [NB100-56114] -  Formalin-fixed paraffin-embedded tissue sections of human gliomas stained for Active/Cleaved Caspase-6 expression using Caspase-6 antibody at 1:2000. Gemistocytoma (low grade tumor) at low (A) and high (B) magnification. Two examples of anaplastic, high grade (III) infiltrating gliomas (C and D). Increased active/cleaved Caspase-6 may be seen in high grade, compared to low grade tumors. Hematoxylin-eosin counterstain.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

4 Publications
NBP1-92164
Immunocytochemistry/Immunofluorescence: NAG Antibody [NBP1-92164] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol & the Golgi apparatus.Immunohistochemistry-Paraffin: NAG Antibody [NBP1-92164] - Staining of human heart muscle shows cytoplasmic positivity in myocytes.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP1-52084
Western Blot: Phenylalanine Hydroxylase Antibody [NBP1-52084] - (0.1ug/ml) staining of Mouse (A) and Rat (B) Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: Phenylalanine Hydroxylase Antibody [NBP1-52084] - Staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC-P, PEP-ELISA

1 Publication
NBP1-89979
Immunocytochemistry/Immunofluorescence: Mad Antibody [NBP1-89979] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli and mitochondria.Immunohistochemistry-Paraffin: Mad Antibody [NBP1-89979] - Staining of human testis shows strong nuclear positivity in cells in seminiferus ducts.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP2-24509
Western Blot: AMPD1 Antibody [NBP2-24509] - Analysis of human AMPDA1 in mouse skeletal muscle lysate in the 1) absence, 2) presence of immunizing peptide and 3) rat skeletal muscle using NBP2-24509 at 1 ug/ml.Immunohistochemistry-Paraffin: AMPD1 Antibody [NBP2-24509] - IHC analysis of human skeletal muscle using NBP2-24509 at 10 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC-P

1 Publication
NB100-57493
Western Blot: KIF1B Antibody [NB100-57493] - Detection of Human and Mouse KIF1B on HeLa whole cell lysate using NB100-57493. KIF1B was also immunoprecipitated by rabbit anti-KIF1B antibody NB100-57494.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IP

3 Publications

Related PTMs

Pelger-huet Anomaly has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Pelger-huet Anomaly is also known as pelger-huet anomaly, ovoid neutrophil nuclei, developmental delay, epilepsy and skeletal abnormalities, pelger-huet nuclear anomaly, pelger huet anomaly, pha.